The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.
The recent progress of isoxazole in medicinal chemistry
Open accessAbstract
Isoxazole compounds exhibit a wide spectrum of targets and broad biological activities. Developing compounds with heterocycle rings has been one of the trends. The integration of isoxazole ring can offer improved physical-chemical properties. Because of the unique profiles, isoxazole ring becomes a popular moiety in compounds design. In this review article, the major focus has been paid to the applications of isoxazole compounds in treating multiple diseases, including anticancer, antimicrobial, anti-inflammatory, etc. Strategies for compounds design for preclinical, clinical, and FDA approved drugs were discussed. Also, the emphasis has been addressed to the future perspectives and trend for the application.
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Cites
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Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4
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Metadata
- Authors
- Zhu, J., Mo, J., Lin, H.-Z., Chen, Y., & Sun, H.-P.
- Venue
- Bioorganic & Medicinal Chemistry
- Publisher
- Elsevier BV
- Published
- 2018-07
- Volume
- 26
- Issue
- 12
- Pages
- 3065-3075
- ISSN
- 0968-0896 (ISSN-L)
- OpenAlex
- W2806424166
- Cited by
- 417
- References
- 51
- FWCI
- 11.04
- Type
- journal article
- Language
- en
- Open access
- green
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- Zhu, J., Mo, J., Lin, H.-Z., Chen, Y., & Sun, H.-P. (2018). The recent progress of isoxazole in medicinal chemistry. Bioorganic & Medicinal Chemistry. https://doi.org/10.1016/j.bmc.2018.05.013
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
