Management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the Infectious Diseases Society of America and the American Thoracic Society.

Kalil, Andre C., Metersky, Mark L., Klompas, Michael, Muscedere, John, Sweeney, Daniel A., Palmer, Lucy B., Napolitano, Lena M., O'Grady, Naomi P., Bartlett, John G., Carratalà, Jordi, El Solh, Ali A., Ewig, Santiago, Fey, Paul D., File, Thomas M., Restrepo, Marcos I., Roberts, Jason A., Waterer, Grant W., Cruse, Peggy, Knight, Shandra L., Brozek, Jan L.·2016·Clinical Infectious Diseases

DOI 10.1093/cid/ciw353

Cites (363)

Items 201–363 of 363

Early- and Late-Onset Pneumonia: Is This Still a Useful Classification?
Petra Gastmeier, D. Sohr, Christine Geffers · 2009 · Antimicrobial Agents and Chemotherapy
Early Antibiotic Discontinuation in Patients With Clinically Suspected Ventilator-Associated Pneumonia and Negative Quantitative Bronchoscopy Cultures*
Kirthana Raman, Michael D. Nailor, David P. Nicolau, Jaber Aslanzadeh, Michelle Nadeau, Joseph L. Kuti · 2013 · Critical Care Medicine
Impact of adequate empirical combination therapy on mortality from bacteremic Pseudomonas aeruginosapneumonia
So-Youn Park, Hyun Jung Park, Song Mi Moon, Ki–Ho Park, Yong Pil Chong, Mi‐Na Kim, Sung‐Han Kim, Sang‐Oh Lee, Yang Soo Kim, Jun Hee Woo et al. · 2012 · BMC Infectious Diseases
Management of Bacterial Pneumonia in Ventilated Patients
G. Umberto Meduri, Richard G. Wunderink, Kenneth V. Leeper · 1992 · CHEST Journal
Systematic surveillance cultures as a toolto predict involvement of multidrug antibiotic resistant bacteria in ventilator-associated pneumonia
Pieter O Depuydt, Dominique Benoît, Dirk Vogelaers · 2007 · Intensive Care Medicine
A prospective study of the diagnostic utility of sputum Gram stain in pneumonia
Stavros Anevlavis, Niki Petroglou, Athanasios Tzavaras · 2009 · Journal of Infection
β‐ L actam pharmacokinetics and pharmacodynamics in critically ill patients and strategies for dose optimization: A structured review
Mahipal Sinnollareddy, Michael Stephen Roberts, Jeffrey Lipman, Jason Alexander Roberts · 2012 · Clinical and Experimental Pharmacology and Physiology
Aerosolized Tobramycin in The Treatment of Ventilator-Associated Pneumonia: A Pilot Study
Ali H. HALLAL, Stephen M. Cohn, Nicholas Namias · 2007 · Surgical Infections
Pneumonia associated with invasive and noninvasive ventilation: an analysis of the German nosocomial infection surveillance system database
Anke Kohlenberg, Frank Schwab, Michael Behnke, Christine Geffers, Petra Gastmeier · 2010 · Intensive Care Medicine
Determinants of prescription and choice of empirical therapy for hospital-acquired and ventilator-associated pneumonia
Jordi Rello, Marta Ulldemolins, Thiago Costa Lisboa, Despoina Koulenti, Rafael Máñez, Ignacio Martín‐Loeches, Jan J. De Waele, Christian Putensen, Muhammet Güven, Maria Deja et al. · 2010 · European Respiratory Journal
Impact of appropriate antimicrobial treatment on transition from ventilator-associated tracheobronchitis to ventilator-associated pneumonia
Saad Nseir, Ignacio Martín‐Loeches, Demosthenes A. Makris · 2014 · Critical Care
Tobramycin penetration into epithelial lining fluid of patients with pneumonia
Antonio J. Carcas, JOSÉ L. GARCÍA-SATUÉ, Pedro Zapater · 1999 · Clinical Pharmacology & Therapeutics
Trends in Antibiotic Use and Nosocomial Pathogens in Hospitalized Veterans With Pneumonia at 128 Medical Centers, 2006–2010
Barbara Ellen Jones, Makoto Jones, Benedikt David Huttner, Gregory J. Stoddard, Kevin Antoine Brown, Vanessa W Stevens, Tom Greene, Brian C. Sauer, Karl Madaras‐Kelly, Michael A Rubin et al. · 2015 · Clinical Infectious Diseases
Reliability of mini-bronchoalveolar lavage for the measurement of epithelial lining fluid concentrations of tobramycin in critically ill patients
Emmanuel Boselli, Dominique Breilh, Sarah Djabarouti, Christian Guillaume, Thomas R. Rimmele, Jean-Baptiste Gordien, Fabien Xuereb, Marie‐Claude Saux, Bernard Allaouchiche · 2007 · Intensive Care Medicine
Impact of adequacy of initial antimicrobial therapy on the prognosis of patients with ventilator-associated pneumonia
Olivier Leroy, Agnès Meybeck, T. d’Escrivan · 2003 · Intensive Care Medicine
Optimal Doripenem Dosing Simulations in Critically Ill Nosocomial Pneumonia Patients With Obesity, Augmented Renal Clearance, and Decreased Bacterial Susceptibility*
Jason A. Roberts, Jeffrey Lipman · 2012 · Critical Care Medicine
A prospective comparison of nursing home-acquired pneumonia with hospital-acquired pneumonia in non-intubated elderly
Maruyama, T., Niederman, M.S., Kobayashi, T., Kobayashi, H., Takagi, T., D'Alessandro-Gabazza, C.N., Fujimoto, H., Gil Bernabe, P., Hirohata, S., Nakayama, S. et al. · 2008 · Respiratory Medicine
Determining a clinical framework for use of cefepime and -lactam/ -lactamase inhibitors in the treatment of infections caused by extended-spectrum- -lactamase-producing Enterobacteriaceae
Huong Minh Nguyen, Kileen L. Shier, Christopher J. Graber · 2013 · Journal of Antimicrobial Chemotherapy
Imipenem, Meropenem, or Doripenem To Treat Patients with Pseudomonas aeruginosa Ventilator-Associated Pneumonia
Charles Edouard Luyt, Alexandra Aubry, Qin Lü, Maïté Micaëlo, Nicolas Bréchot, Florence Brossier, Hélène Brisson, Jean‐Jacques Rouby, Jean‐Louis Trouillet, Alain Combes et al. · 2013 · Antimicrobial Agents and Chemotherapy
Comparison of clinical cure rates in adults with ventilator-associated pneumonia treated with intravenous ceftazidime administered by continuous or intermittent infusion: A retrospective, nonrandomized, open-label, historical chart review
Leonardo Lorente, Alejandro Jiménez, S Palmero, Juan José Jiménez, Jose Luis Iribarren, M. Cabrera Santana, Maria Mercedes Iniguez de Onzono Martin, María Luisa Mora · 2007 · Clinical Therapeutics
Epidemiology, antibiotic therapy and clinical outcomes of healthcare-associated pneumonia in critically ill patients: a Spanish cohort study
Jordi Vallés, Ignacio Martín‐Loeches, Antoní Torres, Emili Dı́az, Iratxe Seijas, Maria José López, Pau Garro, Carlos Castillo, José Garnacho‐Montero, María del Mar Martín et al. · 2014 · Intensive Care Medicine
Efficacy of Meropenem as Monotherapy in the Treatment of Ventilator-Associated Pneumonia
F. Álvarez Lerma, On Behalf of The Serious Infection Study Group · 2001 · Journal of Chemotherapy
Prolonged use of carbapenems and colistin predisposes to ventilator-associated pneumonia by pandrug-resistant Pseudomonas aeruginosa
Spyros D. Mentzelopoulos, Maria E. Pratikaki, Evangelia D. Platsouka, Helen Kraniotaki, Dimitris Zervakis, Antonia Koutsoukou, Serafim Nanas, O. Paniara, Charis Roussos, Evangelos J. Giamarellos‐Bourboulis et al. · 2007 · Intensive Care Medicine
Diagnostic Implications of Soluble Triggering Receptor Expressed on Myeloid Cells-1 in BAL Fluid of Patients With Pulmonary Infiltrates in the ICU
Nitin J. Anand, Scott Zuick, Julia Klesney‐Tait · 2008 · CHEST Journal
Adjunctive aerosolized colistin for multi-drug resistant gram-negative pneumonia in the critically ill: a retrospective study
Neha Doshi, Charles H. Cook, Kari L. Mount · 2013 · BMC Anesthesiology
Effect of ventilator-associated tracheobronchitis on outcome in patients without chronic respiratory failure: a case–control study
Saad Nseir, Christophe Di Pompéo, Stéphane Soubrier · 2005 · Critical Care
Clinical Significance of Borderline Quantitative Protected Brush Specimen Culture Results
Didier Dreyfuss, Laurence Mier, Geneviève Le Bourdellés · 1993 · American Review of Respiratory Disease
Prediction of Methicillin-Resistant Staphylococcus aureus Involvement in Disease Sites by Concomitant Nasal Sampling
Ari A. Robicsek, Mira T. Suseno, Jennifer L. Beaumont, Richard B. Thomson, Lance R. Peterson · 2007 · Journal of Clinical Microbiology
Effect of vancomycin plus rifampicin in the treatment of nosocomial methicillin-resistant Staphylococcus aureus pneumonia*
Young Ju Jung, Younsuck Koh, Sang‐Bum Hong et al. · 2009 · Critical Care Medicine
Evaluation of tedizolid againstStaphylococcus aureusand enterococci with reduced susceptibility to vancomycin, daptomycin or linezolid
Katie E. Barber, Jordan R. Smith, Animesh Raut · 2015 · Journal of Antimicrobial Chemotherapy
Short-Course Versus Prolonged-Course Antibiotic Therapy for Hospital-Acquired Pneumonia in Critically Ill Adults
Cass Piper Sandoval · 2016 · Critical Care Nurse
Serum procalcitonin for the early recognition of nosocomial infection in the critically ill patients: a preliminary report
Pierre‐Emmanuel Charles, Emmanuel Kus, Serge Aho, Sébastien Prin, Jean‐Marc Doise, Nils‐Olivier Olsson, Bernard Blettery, Jean‐Pierre Quenot · 2009 · BMC Infectious Diseases
Impact of multidrug resistance on Pseudomonas aeruginosa ventilator-associated pneumonia outcome: predictors of early and crude mortality
Carmen Peña, Sílvia Gómez-Zorrilla, Isabel Oriol, Fé Tubau, M.Á. Domínguez, Miquel Pujol, Javier Ariza · 2013 · European Journal of Clinical Microbiology & Infectious Diseases
Feedback dose alteration significantly affects probability of pathogen eradication in nosocomial pneumonia
Francesco Scaglione, Silvano Esposito, Sara Leone, Valentina Lucini, Marilou Pannacci, Lei Ma, George L. Drusano · 2009 · European Respiratory Journal
Elevations in procalcitonin but not C-reactive protein are associated with pneumonia after cardiopulmonary resuscitation
Michael Oppert, Albrecht Reinicke, Christian Eugen Mueller · 2002 · Resuscitation
Early use of imipenem/cilastatin and vancomycin followed by de-escalation versus conventional antimicrobials without de-escalation for patients with hospital-acquired pneumonia in a medical ICU: a randomized clinical trial
Jong Kyoung Kim, Joowon Chung, Sang‐Ho Choi · 2012 · Critical Care
Inadequate treatment of ventilator-associated and hospital-acquired pneumonia: Risk factors and impact on outcomes
Nihal Pişkin, Hande Aydemir, Nefise Öztoprak · 2012 · BMC Infectious Diseases
Contribution of Blinded, Protected Quantitative Specimens to the Diagnostic and Therapeutic Management of Ventilator-Associated Pneumonia
Christian Brun‐Buisson, Muriel sarah Fartoukh, Emmanuèle Lechapt, Stéphanie Honoré, Jean‐Ralph Zahar, Charles Cerf, Bernard Maître · 2005 · CHEST Journal
Treatment of hospital-acquired pneumonia with linezolid or vancomycin: a systematic review and meta-analysis
André C. Kalil, Michael Klompas, Gleb R. Haynatzki, Mark E. Rupp · 2013 · BMJ Open
Methicillin-resistant Staphylococcus aureus nasal colonization is a poor predictor of intensive care unit-acquired methicillin-resistant Staphylococcus aureus infections requiring antibiotic treatment
Kiran V. Sarikonda, Scott T. Micek, Joshua A. Doherty, Richard M. Reichley, David K. Warren, Marin H. Kollef · 2010 · Critical Care Medicine
Efficacy and tolerability of piperacillin/tazobactam versus ceftazidime in association with amikacin for treating nosocomial pneumonia in intensive care patients: a prospective randomized multicenter trial
Francisco Álvarez-Lerma, J. Insausti-Ordeñana, Ricard Jordà‐Marcos · 2001 · Intensive Care Medicine
Validation of Predictors of Adverse Outcomes in Hospital-Acquired Pneumonia in the ICU*
Mariano Esperatti, Miquel Ferrer, Valeria Giunta · 2013 · Critical Care Medicine
Site of infection rather than vancomycin MIC predicts vancomycin treatment failure in methicillin-resistant Staphylococcus aureus bacteraemia
Carla J. Walraven, Mariah North, Lisa R. Marr-Lyon, Paulina Deming, George Sakoulas, Renée-Claude Mercier · 2011 · Journal of Antimicrobial Chemotherapy
The adequacy of timely empiric antibiotic therapy for ventilator-associated pneumonia: An important determinant of outcome
John Muscedere, Andrew F. Shorr, Xuran Jiang, Andrew G. Day, Daren Keith Heyland · 2012 · Journal of Critical Care
Pneumonia treated in the internal medicine department: focus on healthcare-associated pneumonia
Maddalena Giannella, Blanca Pinilla, Josep Anton Capdevila, J. Martínez Alarcón, Patricia Muñóz, Joaquín López Álvarez, Emilio Bouza · 2011 · Clinical Microbiology and Infection
Treatment of severe nosocomial pneumonia: a prospective randomised comparison of intravenous ciprofloxacin with imipenem/cilastatin
A. Torres · 2000 · Thorax
Ventilator-Associated Pneumonia in a Multi-Hospital System Differences in Microbiology by Location
Hilary M. Babcock, Jeanne E. Zack, Teresa Garrison · 2003 · Infection Control and Hospital Epidemiology
Inhibitory Activities of 11 Antimicrobial Agents and Bactericidal Activities of Vancomycin and Daptomycin against Invasive Methicillin-Resistant Staphylococcus aureus Isolates Obtained from 1999 through 2006
Robert L. Holmes, James H. Jorgensen · 2007 · Antimicrobial Agents and Chemotherapy
Diagnosis and Treatment of Ventilator-Associated Pneumonia—Impact on Survival
Timothy R. Sterling, Edward J. Ho, Walter T. Brehm · 1996 · CHEST Journal
Soluble Triggering Receptor Expressed on Myeloid Cell-1 Is Increased in Patients With Ventilator-Associated Pneumonia
Grigory Horonenko, Jeffrey C. Hoyt, Richard Robbins · 2007 · CHEST Journal
Development of a Guideline for the Management of Ventilator-Associated Pneumonia Based on Local Microbiologic Findings and Impact of the Guideline on Antimicrobial Use Practices
Timothy H. Dellit, Jeannie D. Chan, Shawn J. Skerrett · 2008 · Infection Control and Hospital Epidemiology
Monotherapy in serious hospital-acquired infections: a clinical trial of ceftazidime versus imipenem/cilastatin
S. Ragnar Norrby, Roger G. Finch, Michel Pierre Glauser · 1993 · Journal of Antimicrobial Chemotherapy
Efficacy, Safety, and Therapeutic Relevance of Transthoracic Aspiration with Ultrathin Needle in Nonventilated Nosocomial Pneumonia
Jordi Dorca, Federico Manresa, Laura Esteban · 1995 · American Journal of Respiratory and Critical Care Medicine
Comparison of piperacillin/tazobactam and imipenem/cilastatin, both in combination with tobramycin, administered every 6 h for treatment of nosocomial pneumonia
Manjari G. Joshi, Michael H. Metzler, Mary C. McCarthy · 2006 · Respiratory Medicine
The safety of targeted antibiotic therapy for ventilator-associated pneumonia: A multicenter observational study
Ari Robin Joffe, John Muscedere, John C. Marshall · 2008 · Journal of Critical Care
Empirical monotherapy with meropenem in serious bacterial infections
Yves Mouton, Claude Beuscart, the Meropenem Study Group · 1995 · Journal of Antimicrobial Chemotherapy
Diagnostic accuracy of protected catheter sampling in ventilator-associated bacterial pneumonia
Fabienne Brégeon, Laurent Papazian, P. A. Thomas · 2000 · European Respiratory Journal
Risk factors for multidrug-resistant Pseudomonas aeruginosa acquisition. Impact of antibiotic use in a double case–control study
M. Montero, María Sala, Marta Riu et al. · 2009 · European Journal of Clinical Microbiology & Infectious Diseases
Methicillin-resistant Staphylococcus aureus vancomycin susceptibility testing: methodology correlations, temporal trends and clonal patterns
Sebastiaan J. van Hal, Thelma Barbagiannakos, Mark Jones · 2011 · Journal of Antimicrobial Chemotherapy
Pathogens in Early-Onset and Late-Onset Intensive Care Unit–Acquired Pneumonia
Katia M.C. Verhamme, W. De Coster, L. De Roo · 2007 · Infection Control and Hospital Epidemiology
Soluble TREM-1 is not suitable for distinguishing between systemic inflammatory response syndrome and sepsis survivors and nonsurvivors in the early stage of acute inflammation
Christian Bopp, Stefan Hofer, Axel Bouchon · 2009 · European Journal of Anaesthesiology
Pharmacokinetics and Pharmacodynamics of Intravenous Levofloxacin in Patients with Early-Onset Ventilator-Associated Pneumonia
Federico Pea, Elena Di Qual, Aldo Cusenza · 2003 · Clinical Pharmacokinetics
Telavancin for Hospital-Acquired Pneumonia: Clinical Response and 28-Day Survival
G. Ralph Corey, Marin H. Kollef, Andrew F. Shorr, Ethan Rubinstein, Martín E. Stryjewski, Alan Hopkins, Steven L. Barriere · 2014 · Antimicrobial Agents and Chemotherapy
A Clinical Trial Comparing Physician Prompting With an Unprompted Automated Electronic Checklist to Reduce Empirical Antibiotic Utilization
Curtis H. Weiss, David M. DiBardino, Jason Rho, Nina Sung, Brett Collander, Richard G. Wunderink · 2013 · Critical Care Medicine
Ertapenem versus cefepime for initial empirical treatment of pneumonia acquired in skilled-care facilities or in hospitals outside the intensive care unit
Sergey V. Yakovlev, Leonid S. Stratchounski, Gail L. Woods · 2006 · European Journal of Clinical Microbiology & Infectious Diseases
Survey of Health Care–Associated Infections
Shelley S. Magill, Jonathan R. Edwards, Scott K. Fridkin · 2014 · New England Journal of Medicine
Effects of Carbapenem consumption on the prevalence of Acinetobacter infection in intensive care unit patients
Aziz Öğütlü, Ertuğrul Güçlü, Oğuz Karabay, Aylin Çalıca Utku, Nazan Tuna, Mehmet Yahyaoğlu · 2014 · Annals of Clinical Microbiology and Antimicrobials
Piperacillin/Tazobactam vs Imipenem/Cilastatin in the Treatment of Nosocomial Pneumonia—a Double Blind Prospective Multicentre Study
D Schmitt, Eva Leitner, Tobias Welte · 2006 · Infection
Is a Strategy Based on Routine Endotracheal Cultures the Best Way to Prescribe Antibiotics in Ventilator-Associated Pneumonia?
Carlos M. Luna, Sergio Sarquís, Michael S. Niederman · 2013 · CHEST Journal
Effects of Carbapenem Exposure on the Risk for Digestive Tract Carriage of Intensive Care Unit-Endemic Carbapenem-Resistant Pseudomonas aeruginosa Strains in Critically Ill Patients
C. Peña, Ana María Guzmán, C. Suarez, M.Á. Domínguez, Fé Tubau, Miquel Pujol, F. Gudiol, Javier Ariza · 2007 · Antimicrobial Agents and Chemotherapy
Detection and Characterization of Heterogeneous Vancomycin-Intermediate Staphylococcus aureus Isolates in Canada: Results from the Canadian Nosocomial Infection Surveillance Program, 1995-2006
Heather J. Adam, Lisa Louie, Christine Watt · 2009 · Antimicrobial Agents and Chemotherapy
Risk factors for methicillin-resistant Staphylococcus aureus in patients with community-onset and hospital-onset pneumonia
Wooten, D.A., Winston, L.G. · 2013 · Respiratory Medicine
Risk factors for carbapenem-resistant Gram-negative bacteremia in intensive care unit patients
Christina Routsi, Maria E. Pratikaki, Evangelia D. Platsouka · 2013 · Intensive Care Medicine
Diagnostic investigation of ventilator-associated pneumonia using bronchoalveolar lavage: comparative study with a postmortem lung biopsy
Alípio Barbosa Balthazar, Angela von NOWAKONSKI, Eduardo Mello De Capitani · 2001 · Brazilian Journal of Medical and Biological Research
Imipenem resistance of Pseudomonas in pneumonia: a systematic literature review
Marya D. Zilberberg, Joyce Chen, Samir H. Mody · 2010 · BMC Pulmonary Medicine
EMPIRIC MONOTHERAPY VERSUS COMBINATION THERAPY OF NOSOCOMIAL PNEUMONIA IN TRAUMA PATIENTS
Martin A. Croce, Timothy C. Fabian, Ronald M. Stewart · 1993 · The Journal of Trauma: Injury, Infection, and Critical Care
Carbapenems and piperacillin/tazobactam for the treatment of bacteremia caused by extended-spectrum β-lactamase–producing Proteus mirabilis
Hsih-Yeh Tsai, Yen‐Hsu Chen, Hung-Jen Tang · 2014 · Diagnostic Microbiology and Infectious Disease
Efficacy of ertapenem in the treatment of early ventilator-associated pneumonia caused by extended-spectrum β-lactamase-producing organisms in an intensive care unit
Matteo Bassetti, Elda Righi, Roberta Fasce · 2007 · Journal of Antimicrobial Chemotherapy
[Administration of tobramycin aerosols in patients with nosocomial pneumonia: a preliminary study].
Philippe Le Conte, Gille Potel, E. Clementi · 2000 · PubMed
Colistin against colistin-only-susceptible Acinetobacter baumannii-related infections: Monotherapy or combination therapy?
Funda Şimşek, Habip Gedık, Taner Yıldırmak · 2012 · Indian Journal of Medical Microbiology
Triggering receptor expressed on myeloid cells-1 expression on monocytes is associated with inflammation but not with infection in acute pancreatitis
Eduardo Antonio Ferat-Osorio, Isabel Wong‐Baeza, Noemí Esquivel-Callejas, Silvia Figueroa-Figueroa, Andrés Duarte‐Rojo, Gilberto Guzmán‐Valdivia Gómez, Heriberto Rodea Rosas, Rubén Torres-González, Patricio Sánchez-Fernández, Lourdes Arriaga‐Pizano et al. · 2009 · Critical Care
Combination therapy versus monotherapy: a randomised pilot study on the evolution of inflammatory parameters after ventilator associated pneumonia [ISRCTN31976779]
Pierre Damas, Christophe Garweg, Mehran Monchi, Monique Nys, Jean-Luc Canivet, Didier Ledoux, Jean‐Charles Preiser · 2006 · Critical Care
Ventilator-associated pneumonia due to meticillin-resistant Staphylococcus aureus: risk factors and outcome in a large general hospital
Emilio Bouza, Maddalena Giannella, Eleonora Bunsow · 2012 · Journal of Hospital Infection
De-Escalation Therapy: Is It Valuable for the Management of Ventilator-Associated Pneumonia?
Michael S. Niederman, Vasiliki Soulountsi · 2011 · Clinics in Chest Medicine
Antimicrobial use, incidence, etiology and resistance patterns in bacteria causing ventilator-associated pneumonia in a clinical-surgical intensive care unit
Michel Rodrigues Moreira, Munick Paula Guimarães, Aurélia Aparecida de Araújo Rodrigues · 2013 · Revista da Sociedade Brasileira de Medicina Tropical
Differences in potency and categorical agreement between colistin and polymyxin B when testing 15,377 clinical strains collected worldwide
Helio Silva Sader, Paul R. Rhomberg, David J. Farrell · 2015 · Diagnostic Microbiology and Infectious Disease
Vancomycin Susceptibility Trends and Prevalence of Heterogeneous Vancomycin-Intermediate Staphylococcus aureus in Clinical Methicillin-Resistant S. aureus Isolates
Adam M. Pitz, Fang Yu, Elizabeth D. Hermsen, Mark E. Rupp, Paul D. Fey, Keith M. Olsen · 2010 · Journal of Clinical Microbiology
Outbreaks of Staphylococcus aureus infections during treatment of late onset pneumonia with ciprofloxacin in a prospective, randomized study
C. Manhold, U. v. Rolbicki, Rainer Brase · 1998 · Intensive Care Medicine
Durée de l’antibiothérapie lors du traitement des pneumopathies acquises sous ventilation mécanique : comparaison entre sept jours et dix jours. Étude pilote
M. Fekih Hassen, Soufia Ayed, Habiba Ben Sik Ali, Rim Gharbi, Soudani Marghli, Souheil Elatrous · 2008 · Annales Françaises d Anesthésie et de Réanimation
Is the Present Definition of Health Care–Associated Pneumonia the Best Way to Define Risk of Infection with Antibiotic-Resistant Pathogens?
Vanessa L. Yap, Debapriya Datta, Mark L. Metersky · 2012 · Infectious Disease Clinics of North America
Duration of Antibiotic Therapy for Ventilator-Associated Pneumonia Caused by Non-Fermentative Gram-Negative Bacilli
Traci L. Hedrick, Shannon T. McElearney, Robert Lane Smith · 2007 · Surgical Infections
Editorial Commentary: Combination Therapy for Pseudomonas aeruginosa Bacteremia: Where Do We Stand?
Mical Paul, Leonard Leibovici · 2013 · Clinical Infectious Diseases
Use of Quantitative Cultures and Reduced Duration of Antibiotic Regimens for Patients with Ventilator-Associated Pneumonia to Decrease Resistance in the Intensive Care Unit
Jean E. Chastre, Charles‐Édouard Luyt, Alain Combes · 2006 · Clinical Infectious Diseases
Quantitative Cultures for Diagnosing Ventilator-Associated Pneumonia: A Critique
Shigeki Fujitani, Victor L. Yu · 2006 · Clinical Infectious Diseases
Penetration of Netilmicin in the Lower Respiratory Tract after Once-Daily Dosing
Y. Valcke, Dirk Vogelaers, FRANCIS A. COLARDYN · 1992 · CHEST Journal
Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1) as a Diagnostic Marker of Ventilator-Associated Pneumonia
Steven J. Palazzo, Terri A. Simpson, Jillian M. Simmons · 2012 · Respiratory Care
Hospital-Acquired Pneumonia in Critically Ill Patients: Factors Associated with Episodes Due to Imipenem-Resistant Organisms
O. Leroy, T. d’Escrivan, Patrick Devos · 2005 · Infection
Bacteremic pneumonia caused by extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae: Appropriateness of empirical treatment matters
Wan-Ling Cheng, Po‐Ren Hsueh, Ching‐Chi Lee, Chia‐Wen Li, Ming-Ji Li, Chia‐Ming Chang, Nan–Yao Lee, Wen‐Chien Ko · 2014 · Journal of Microbiology Immunology and Infection
Evaluation of endotoxin release and cytokine production induced by antibiotics in patients with Gram-negative nosocomial pneumonia
Bernardo C Maskin, Patricia A. Fontán, Emma G. Spinedi · 2002 · Critical Care Medicine
Providing appropriate antimicrobial therapy in the intensive care unit: Surveillance vs. de-escalation*
Marin H. Kollef · 2006 · Critical Care Medicine
Outcomes of Ventilated COPD Patients with Nosocomial Tracheobronchitis: A Case-Control Study
Saad Nseir, Christophe Di Pompéo, Stéphane Soubrier · 2004 · Infection
Carbapenems for the treatment of immunocompetent adult patients with nosocomial pneumonia
Ilias Ι. Siempos, Konstantinos Z. Vardakas, Katerina G. Manta, Matthew E. Falagas · 2007 · European Respiratory Journal
The impact of vancomycin susceptibility on treatment outcomes among patients with methicillin resistant Staphylococcus aureusbacteremia
Hitoshi Honda, Christopher D. Doern, W. Michael Dunne, David K. Warren · 2011 · BMC Infectious Diseases
Multicenter Survey on Hospital-acquired Pneumonia and the Clinical Efficacy of First-line Antibiotics in Japan
Akira Watanabe, Katsunori Yanagihara, Shigeru Kohno · 2008 · Internal Medicine
Worldwide Experience with the Use of Doripenem against Extended-Spectrum-β-Lactamase-Producing and Ciprofloxacin-Resistant Enterobacteriaceae : Analysis of Six Phase 3 Clinical Studies
Koné Kaniga, Robert K. Flamm, Shin-Yir Tong · 2010 · Antimicrobial Agents and Chemotherapy
Levofloxacin for Treatment of Ventilator-Associated Pneumonia: A Subgroup Analysis from a Randomized Trial
Andrew F. Shorr, Neringa Zadeikis, William L. Jackson · 2005 · Clinical Infectious Diseases
Meta-analysis of Randomized Controlled Trials of Vancomycin for the Treatment of Patients With Gram-Positive Infections: Focus on the Study Design
Konstantinos Z. Vardakas, Michail N. Mavros, Nikolaos S. Roussos, Matthew E. Falagas · 2012 · Mayo Clinic Proceedings
Inhaled Colistin for Treatment of Pneumonia due to Colistin-Only-SusceptibleAcinetobacter baumannii
Hee Kyoung Choi, Young Keun Kim, Hyo Youl Kim · 2013 · Yonsei Medical Journal
Safety and efficacy of polymyxin B in multidrug resistant gram-negative severe sepsis and septic shock
Ayanava Majumdar, Purnendu Sekhar Das · 2008 · Indian Journal of Critical Care Medicine
Diagnostic Utility of Plasma Procalcitonin for Nosocomial Pneumonia in the Intensive Care Unit Setting
John Dallas, Sarah M. Brown, Karl G. Hock · 2011 · Respiratory Care
Hospital-acquired pneumonia: microbiological data and potential adequacy of antimicrobial regimens
O. Leroy, P. Giradie, Yazdan Yazdanpanah · 2002 · European Respiratory Journal
Hospital-Acquired Pneumonia Developed in Non-Intensive Care Units
Ebru Çakır Edis, Osman Nuri Hatipoğlu, İlker Yılmam · 2009 · Respiration
Anti-Pseudomonas activity in bronchial secretions of patients receiving amikacin or tobramycin as a continuous infusion
Giorgio Mombelli, Lenny Coppens, J.P. Thys · 1981 · Antimicrobial Agents and Chemotherapy
Nosocomial pneumonia: Comparative multicentre trial between monotherapy with cefotaxime and treatment with antibiotic combinations
Manuel Fernández Guerrero, C. Arnau, Luís Valdés · 1991 · Infection
Analysis of Phase 3 telavancin nosocomial pneumonia data excluding patients with severe renal impairment and acute renal failure
Antoní Torres, E. Rubinstein, G. Ralph Corey · 2014 · Journal of Antimicrobial Chemotherapy
Comparison of polymyxin B with other antimicrobials in the treatment of ventilator-associated pneumonia and tracheobronchitis caused by Pseudomonas aeruginosa or Acinetobacter baumannii
Maria Helena Rigatto, Vanessa Bley Ribeiro, Daniele Konzen · 2012 · Infection
Comparison of Ceftriaxone with Cefotaxime in Serious Chest Infections
John H. Reeves, Gary M. Russell, John F. Cade · 1989 · CHEST Journal
Treatment of Pneumonia in Mechanically Ventilated Trauma Patients
Hiram C. Polk · 1997 · Archives of Surgery
Do quantitative cultures of protected brush specimens modify the initial empirical therapy in ventilated patients with suspected pneumonia?
Felipe Rodrı́guez de Castro, Jordi Solé‐Violán, A Aranda Leon · 1996 · European Respiratory Journal
Bacteremia and Ventilator-Associated Pneumonia: A Marker for Contemporaneous Extra-Pulmonic Infection
Anastasia Kunac, Ziad C. Sifri, Alicia M. Mohr, Helen Horng, Robert F. Lavery, David H. Livingston · 2013 · Surgical Infections
Comparison of bronchoscopic diagnostic techniques with histological findings in brain dead organ donors without suspected pneumonia.
Jordi Solé‐Violán, Felipe Rodrı́guez de Castro, A. Rey · 1996 · Thorax
Comparative study of the antibacterial activity of amikacin and tobramycin during Pseudomonas pulmonary infection in patients with cystic fibrosis
Jack Lévy, Daniel Baran, Jean A. Klastersky · 1982 · Journal of Antimicrobial Chemotherapy
Controversies in Ventilator-Associated Pneumonia
Alain Combes, Charles‐Édouard Luyt, Jean‐Louis Trouillet · 2010 · Seminars in Respiratory and Critical Care Medicine
Ventilator-associated pneumonia
Grant Edward O’Keefe, Ellen Caldwell, Joseph Cuschieri, Mark M. Wurfel, Heather Leigh Evans · 2012 · The Journal of Trauma: Injury, Infection, and Critical Care
Association of ertapenem and antipseudomonal carbapenem usage and carbapenem resistance in Pseudomonas aeruginosa among 12 hospitals in Queensland, Australia
David A. J. McDougall, Anthony Park Morton, E Geoffrey Playford · 2012 · Journal of Antimicrobial Chemotherapy
Prognostic factors of nosocomial pneumonia in general wards: a prospective multivariate analysis in Japan
Yoshihisa Takano, O. SAKAMOTO, M. SUGA · 2002 · Respiratory Medicine
Comparative clinical trial of ceftazidime and imipenem/cilastatin in patients with severe nosocomial pneumonias and septicaemias
Ulrich Hartenauer · 1990 · Journal of Hospital Infection
Empirical Antibiotic Therapy for Ventilator-Associated Pneumonia
Joseph M. Swanson, Diana L. Wells · 2013 · Antibiotics
ICU-Acquired Pneumonia With or Without Etiologic Diagnosis
Valeria Giunta, Miquel Ferrer, Mariano Esperatti · 2013 · Critical Care Medicine
Diagnostic implications of soluble triggering receptor expressed on myeloid cells-1 in patients with acute respiratory distress syndrome and abdominal diseases: a preliminary observational study
Paula Ramírez, Pedro Kot, Verónica Martí · 2011 · Critical Care
The accuracy of Gram stain of respiratory specimens in excluding Staphylococcus aureus in ventilator-associated pneumonia
Tamar Gottesman, Orit Yossepowitch, Evgenia Lerner · 2014 · Journal of Critical Care
In Vitro Activity of β-Lactam Antimicrobial Agents in Combination with Aztreonam Tested Against Metallob-β-Lactamase-Producing Pseudomonas aeruginosa and Acinetobacter baumannii
Helio Silva Sader, Paul R. Rhomberg, Ronald N. Jones · 2005 · Journal of Chemotherapy
Validation of an algorithm based on direct examination of specimens in suspected ventilator-associated pneumonia
Anne Veinstein, Christian Brun‐Buisson, Nicolas Derrode · 2006 · Intensive Care Medicine
Diagnostic value of bronchoalveolar lavage in patients with opportunistic and nonopportunistic bacterial pneumonia
Klaus Dalhoff, Jörg Braun, R. Lipp · 1993 · Infection
Management of nosocomial pneumonia on a medical ward: a comparative study of outcomes and costs of invasive procedures
Bertrand Herer, C. Fuhrman, Z. Gazevic · 2009 · Clinical Microbiology and Infection
Methicillin-resistantStaphylococcus aureusnosocomial pneumonia patients treated with ceftaroline: retrospective case series of 10 patients
Timothy R. Pasquale, Michael J. Tan, Tamara L. Trienski · 2013 · Journal of Chemotherapy
A Randomized Study of Sequential Intravenous/Oral Moxifloxacin in Comparison to Sequential Intravenous Ceftriaxone/Oral Cefuroxime Axetil in Patients with Hospital-Acquired Pneumonia
G. Höffken, Jürgen Barth, E. Rubinstein · 2007 · Infection
Risk factors and evolution of Ventilator-associated pneumonia by Staphylococcus aureus sensitive or resistant to oxacillin in patients at the intensive care unit of a Brazilian University Hospital
Michel Rodrigues Moreira, Renata Lima Cardoso, Alair Benedito de Almeida · 2008 · The Brazilian Journal of Infectious Diseases
De-escalation in lower respiratory tract infections
Thiago Costa Lisboa, Jordi Rello · 2006 · Current Opinion in Pulmonary Medicine
Étude phare. Étude comparative de l'association céfépime-amikacine versus ceftazidime en association avec l'amikacine dans le traitement des pneumonies nosocomiales chez les patients ventilés
Gilles Beaucaire, M. H. Nicolas, Céline Marie Pauline Martin · 1999 · Annales Françaises d Anesthésie et de Réanimation
Hypoxia during bronchoalveolar lavage
Peter G. Gibson, Samuel N. Breit, D. H. Bryant · 1990 · Australian and New Zealand Journal of Medicine
Tracheal aspirate Gram stain has limited sensitivity and specificity for detecting Staphylococcus aureus
Sodienye Tetenta, Mark L. Metersky · 2010 · Respirology
Pefloxacin versus imipenem in the therapy of nosocomial lung infections of intensive care unit patients
Helen Giamarellou, Konstantinos E. Mandragos, P. Bechrakis · 1990 · Journal of Antimicrobial Chemotherapy
Dose finding study on the efficacy and safety of ritipenem in complicated urinary tract infections.
W Bischoff, R Herceg, D Sassella · 1995 · PubMed
Questionable Superiority of Linezolid for Methicillin-Resistant Staphylococcus aureus Nosocomial Pneumonia: Watch Where You Step
Tim Lahey · 2012 · Clinical Infectious Diseases
Factores de riesgo y pronósticos de la neumonía nosocomial en los pacientes no ingresados en unidades de cuidados intensivos
Bienvenido Barreiro-López, Josep Maria Tricas, E. Mauri, Salvador Quintana, Javier Garau · 2005 · Enfermedades Infecciosas y Microbiología Clínica
Correlation between the Consumption of Meropenem or Doripenem and Meropenem Susceptibility of Pseudomonas aeruginosa in a University Hospital in Japan
Koji Miyawaki, Yoshihiro Miwa, Masafumi Seki · 2012 · Biological and Pharmaceutical Bulletin
Ceftazidim mit und ohne Tobramycin versus Azlocillin plus Tobramycin in der Therapie bronchopulmonaler Infektionen bei Intensivpatienten
S. Kljucar, M. Heimesaat, E. von Pritzbuer · 1987 · Infection
Subthreshold Quantitative Bronchoalveolar Lavage: Clinical and Therapeutic Implications
Ajai Kumar Malhotra, Omer J. Riaz, Therèse M. Duane, Michel B. Aboutanos, Aaron E. Goldberg, Karen M. Smalara, Christopher Todd Borchers, Nancy R. Martin, Rao R. Ivatury · 2008 · The Journal of Trauma: Injury, Infection, and Critical Care
Prospective, Randomized Comparison of Intravenous and Oral Ciprofloxacin with Intravenous Ceftazidime in the Treatment of Nosocomial Pneumonia
Raphael Saginur, Gary E Garber, Gail Elizabeth Darling · 1996 · Canadian Journal of Infectious Diseases and Medical Microbiology
Treatment of ventilator-associated pneumonia with piperacillin-tazobactum and amikacin vs cefepime and levofloxacin: A randomized prospective study
Parul LNU, Syed Moied Ahmed, J. Choudhary · 2007 · Indian Journal of Critical Care Medicine
Empiric, Broad-Spectrum Antibiotic Therapy with an Aggressive De-Escalation Strategy Does Not Induce Gram-Negative Pathogen Resistance in Ventilator-Associated Pneumonia
Michael L. Hibbard, Tammy R. Kopelman, Patrick J. O’Neill · 2010 · Surgical Infections
[Diagnostic value of procalcitonin in ventilator associated pneumonia].
Cheng-dun Zhou, Zeyuan Lu, Nan-zheng Ren · 2006 · PubMed
Diagnosis of nosocomial pneumonia in medical ward: repeatability of the protected specimen brush
Bertrand Herer, C. Fuhrman, Dominique Demontrond · 2001 · European Respiratory Journal
Hospital-acquired pneumonia in nonintensive care unit wards
Meltem Avcı, Onur Özgenç, Ayten Coşkuner · 2010 · TURKISH JOURNAL OF MEDICAL SCIENCES
Addition of rifampin to vancomycin for the treatment of pneumonias due to methicillin-resistant Staphylococcus aureus: Caveat emptor*
Keith M. Ramsey, Mark A. Mazer · 2009 · Critical Care Medicine
The Effect of Blind-Protected Specimen Brush Sampling on Antibiotic Use in Patients with Suspected Ventilator-Associated Pneumonia
Paul Ellis Marik, Joseph Lynott, Michele Croxton · 2001 · Journal of Intensive Care Medicine
Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic Treatment for Hospital-Acquired Pneumonia
Linda J Lux, Rachael Posey, Lindsay S Daniels, David C. Henke, Carolyn G. Durham, Daniel E Jonas, Kathleen N Lohr · 2014 · Europe PMC (PubMed Central)
The “De-escalation Concept” and Antibiotic De-escalation
Luís Fernando Aranha Camargo · 2013 · Shock
The Effect of Blind-Protected Specimen Brush Sampling on Antibiotic Use in Patients with Suspected Ventilator-Associated Pneumonia
Paul Ellis Marik, Joseph Lynott, Michele Croxton · 2001 · Journal of Intensive Care Medicine
Diagnostic value of procalcitonin in ventilator associated pneumonia
周承惇, 陆泽元, 任南征 · 2006 · Chin Crit Care Med
The Importance of Pathogen Identification in the Success of Treatment of Hospital Acquired Pneumonias
Ebru Çakır Edis, Osman Nuri Hatipoğlu, İlker Yılmam · 2010 · Turkish Thoracic Journal
Hastane kökenli pnömonilerde etken tespitinin tedavi başarısına etkisi
Ebru Çakır Edis, Osman Nuri Hatipoğlu, İlker Yilman · 2010 · Trakya University's Institutional Open Access System (Trakya University)