Management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the Infectious Diseases Society of America and the American Thoracic Society.
Open accessAbstract
It is important to realize that guidelines cannot always account for individual variation among patients. They are not intended to supplant physician judgment with respect to particular patients or special clinical situations. IDSA considers adherence to these guidelines to be voluntary, with the ultimate determination regarding their application to be made by the physician in the light of each patient's individual circumstances. These guidelines are intended for use by healthcare professionals who care for patients at risk for hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP), including specialists in infectious diseases, pulmonary diseases, critical care, and surgeons, anesthesiologists, hospitalists, and any clinicians and healthcare providers caring for hospitalized patients with nosocomial pneumonia. The panel's recommendations for the diagnosis and treatment of HAP and VAP are based upon evidence derived from topic-specific systematic literature reviews.
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In many RCTs of shorter versus longer antimicrobial courses for specific conditions, the shorter course was as effective as the longer course but associated with fewer adverse consequences.
“In many of the trials, the shorter course was just as effective as the longer course but associated with fewer adverse consequences.”
From Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021 (2021) · cites this paper as [288]
Critically ill patients often receive antimicrobials for more days than necessary.
“however, critically ill patients often receive antimicrobials for more days than necessary [288, 301, 306].”
From Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021 (2021) · cites this paper as [288]
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- Authors
- Kalil, A. C., Metersky, M. L., Klompas, M., Muscedere, J., Sweeney, D. A., Palmer, L. B., Napolitano, L. M., O'Grady, N. P., Bartlett, J. G., Carratalà, J., El Solh, A. A., Ewig, S., Fey, P. D., File, T. M., Restrepo, M. I., Roberts, J. A., Waterer, G. W., Cruse, P., Knight, S. L., & Brozek, J. L.
- Affiliations
- Department of Internal Medicine, Division of Infectious Diseases, University of Nebraska Medical Center, Omaha
- University of Connecticut (US)
- Brigham and Women's Hospital (US)
- Queen's University (CA)
- University of California San Diego (US)
- State University of New York (US)
- University of Michigan (US)
- Department of Critical Care Medicine, National Institutes of Health, Bethesda
- Johns Hopkins University (US)
- Bellvitge University Hospital (ES)
- Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University at Buffalo, Veterans Affairs Western New York Healthcare System, New York
- Augusta-Kranken-Anstalt (DE)
- Nebraska Medical Center (US)
- Summa Health System (US)
- The University of Texas at San Antonio Health Science Center (US)
- The University of Queensland (AU)
- The University of Western Australia (AU)
- National Jewish Health (US)
- Department of Clinical Epidemiology and Biostatistics and Department of Medicine, McMaster University, Hamilton, Ontario, Canada
- ORCID
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2016-07-14
- Volume
- 63
- Issue
- 5
- Pages
- e61-e111
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- PMC
- PMC4981759
- OpenAlex
- W2473016454
- Semantic Scholar
- cc67f6fcef3f691050f3a9c18034f837b8e242f9
- Cited by
- 3,892
- References
- 363
- Citations by year
- 2026: 333 · 2025: 355 · 2024: 367 · 2023: 477 · 2022: 493 · 2021: 448 · 2020: 415 · 2019: 351 · 2018: 328 · 2017: 263 · 2016: 50 · 2015: 1 · 2014: 2
- FWCI
- 300.13
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Clinical Infectious Diseases (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Dipòsit Digital de la Universitat de Barcelona (Universitat de Barcelona) (publishedVersion, cc-by)
- HighWire Press Open Archive (submittedVersion)
- RECERCAT (Consorci de Serveis Universitaris de Catalunya) (submittedVersion, cc-by)
- Funders
- National Heart, Lung, and Blood Institute
- NIH
- Topics
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Nosocomial Infections in ICU
- Health Sciences › Medicine › Epidemiology › Pneumonia and Respiratory Infections
- Health Sciences › Medicine › Infectious Diseases › Infection Control in Healthcare
- Keywords
- nosocomial pneumonia, ventilator-associated pneumonia, pneumonia diagnosis, pneumonia treatment, critically ill patients, hospitalized adults
- MeSH terms
- Adult, Anti-Bacterial Agents, Bacteriological Techniques, Cross Infection, Humans, United States, Pneumonia, Bacterial, Drug Resistance, Multiple, Bacterial, Pneumonia, Ventilator-Associated
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