The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Correlation of sperm motility with mitochondrial enzymatic activities
Open accessAbstract
Until now, little attention has been paid to the contribution of mitochondrial dysfunction to germinal tissue disorders. The target of this study was to investigate the relationship between sperm motility and mitochondrial respiratory chain enzyme activities. The results obtained showed that semen samples of control individuals (n = 33) have substantially higher activities of complexes I, II, and IV compared with those of asthenozoospermic subjects (n = 86). Moreover, a direct and positive correlation was found in the whole population studied between spermatozoa motility and all the mitochondrial respiratory complex activities assayed (I, II, I+III, II+III, and IV). The ratio of these enzymes to citrate synthase (a reliable enzymatic marker of mitochondrial volume) activities did not correlate with sperm motility. This suggests that motility depends largely on the mitochondrial volume within the sperm midpiece. These observations could be of physiopathological relevance because they suggest that factors affecting the mitochondrial energy production could be then responsible for particular cases of idiopathic asthenozoospermia.
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Cites
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Lowry, O., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 317,331
AN ELECTRON-TRANSPORT SYSTEM ASSOCIATED WITH THE OUTER MEMBRANE OF LIVER MITOCHONDRIA
Sottocasa, G. L., Kuylenstierna, B., Ernster, L., & Bergstrand, A. (1967) · The Journal of Cell Biology · doi:10.1083/jcb.32.2.415 · Cited by 2,317
Laboratory manual for the examination of human semen and semen-cervical mucus interaction.
Ma, B., Moghissi, K. S., ELIASSON, R., Ca, P., Aj, G., & Mr, P. (1980) · Cited by 2,209
Srere, P. A. (1969) · Methods in Enzymology · doi:10.1016/0076-6879(69)13005-0 · Cited by 2,005
Diseases of the mitochondrial DNA
Wallace, D. C. (1992) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.61.070192.005523 · Cited by 1,319
[45] Cytochrome oxidase from beef heart mitochondria
Wharton, D. C., & Tzagoloff, A. (1967) · Methods in Enzymology · doi:10.1016/0076-6879(67)10048-7 · Cited by 1,261
[58] Preparation of succinate dehydrogenase and reconstitution of succinate oxidase
King, T. E. (1967) · Methods in Enzymology · doi:10.1016/0076-6879(67)10061-x · Cited by 531
Reactive oxygen species and human spermatozoa: physiology and pathology
GRIVEAU, J. F., & LANNOU, D. L. (1997) · International Journal of Andrology · doi:10.1046/j.1365-2605.1997.00044.x · Cited by 522
Johns, D. R. (1995) · New England Journal of Medicine · doi:10.1056/nejm199509073331007 · Cited by 446
Frank, S. A., & Hurst, L. D. (1996) · Nature · doi:10.1038/383224a0 · Cited by 330
Cited by
Wallace, D. C. (2005) · Annual Review of Genetics · doi:10.1146/annurev.genet.39.110304.095751 · Cited by 3,185
Genome sequence, comparative analysis and haplotype structure of the domestic dog
members, B. S. P., Lindblad-Toh, K., Wade, C. M., Mikkelsen, T. S., Karlsson, E. K., Jaffe, D. B., Kamal, M., Clamp, M., Chang, J. L., Kulbokas, E. J., et al. (2005) · Nature · doi:10.1038/nature04338 · Cited by 2,568
Ramalho-Santos, J., Varum, S., Amaral, S., Mota, P. C., Sousa, A. P., & Amaral, A. (2009) · Human Reproduction Update · doi:10.1093/humupd/dmp016 · Cited by 482
The role of mitochondria in energy production for human sperm motility
Piomboni, P., Focarelli, R., Stendardi, A., Ferramosca, A., & Zara, V. (2012) · International Journal of Andrology · doi:10.1111/j.1365-2605.2011.01218.x · Cited by 458
Why Do We Still Have a Maternally Inherited Mitochondrial DNA? Insights from Evolutionary Medicine
Wallace, D. C. (2007) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.76.081205.150955 · Cited by 363
Metadata
- Authors
- Ruiz-Pesini, E., Diez, C., Lapeña, A. C., Pérez-Martos, A., Montoya, J., Alvarez, E., Arenas, J., & López-Pérez, M. J.
- Venue
- Clinical Chemistry
- Publisher
- Oxford University Press (OUP)
- Published
- 1998-08-01
- Volume
- 44
- Issue
- 8
- Pages
- 1616-1620
- ISSN
- 0009-9147 (ISSN-L)
- 1530-8561
- OpenAlex
- W2159031872
- Cited by
- 293
- References
- 21
- FWCI
- 3.42
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Ruiz-Pesini, E., Diez, C., Lapeña, A. C., Pérez-Martos, A., Montoya, J., Alvarez, E., Arenas, J., & López-Pérez, M. J. (1998). Correlation of sperm motility with mitochondrial enzymatic activities. Clinical Chemistry. https://doi.org/10.1093/clinchem/44.8.1616
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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