Diseases of the mitochondrial DNA

Marked decrease of mitochondrial DNA with multiple deletions in a patient with familial mitochondrial myopathy

Otsuka, M., Niijima, K., Mizuno, Y., Yoshida, M., Kagawa, Y., & Ohta, S. (1990) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(90)92079-f · Cited by 30 · see citing works

Biochemistry and molecular cell biology of diabetic complications

Brownlee, M. (2001) · Nature · doi:10.1038/414813a · Cited by 9,107 · see citing works

Oxidative stress and diabetic complications

Giacco, F., & Brownlee, M. (2010) · Circulation Research · doi:10.1161/circresaha.110.223545 · Cited by 5,461 · see citing works

The Pathobiology of Diabetic Complications

Brownlee, M. (2005) · Diabetes · doi:10.2337/diabetes.54.6.1615 · Cited by 5,339 · see citing works

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

Nishikawa, T., Edelstein, D., Du, X. L., Yamagishi, S.-I., Matsumura, T., Kaneda, Y., Yorek, M. A., Beebe, D., Oates, P. J., Hammes, H.-P., et al. (2000) · Nature · doi:10.1038/35008121 · Cited by 4,277 · see citing works

A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Wallace, D. C. (2005) · Annual Review of Genetics · doi:10.1146/annurev.genet.39.110304.095751 · Cited by 3,185 · see citing works

Oxidative stress hypothesis in Alzheimer’s disease

Markesbery, W. R. (1997) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(96)00629-6 · Cited by 2,383 · see citing works

Transcriptional paradigms in mammalian mitochondrial biogenesis and function

Scarpulla, R. C. (2008) · Physiological Reviews · doi:10.1152/physrev.00025.2007 · Cited by 1,666 · see citing works

Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age

Corral-Debrinski, M., Horton, T., Lott, M. T., Shoffner, J. M., Flint Beal, M., & Wallace, D. C. (1992) · Nature Genetics · doi:10.1038/ng1292-324 · Cited by 890 · see citing works

Mitochondrial Signaling

Butow, R. A., & Avadhani, N. G. (2004) · Molecular Cell · doi:10.1016/s1097-2765(04)00179-0 · Cited by 882 · see citing works

Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans

Palikaras, K., Lionaki, E., & Tavernarakis, N. (2015) · Nature · doi:10.1038/nature14300 · Cited by 770 · see citing works

Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency

Bourgeron, T., Rustin, P., Chretien, D., Birch-Machin, M., Bourgeois, M., Viegas-Péquignot, E., Munnich, A., & Rötig, A. (1995) · Nature Genetics · doi:10.1038/ng1095-144 · Cited by 730 · see citing works

A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes.

Ishii, N., Fujii, M., Hartman, P. S., Tsuda, M., Yasuda, K., Senoo-Matsuda, N., Yanase, S., Ayusawa, D., & Suzuki, K. (1998) · Nature · doi:10.1038/29331 · Cited by 687 · see citing works

Transcriptional coactivator PGC-1α controls the energy state and contractile function of cardiac muscle

Arany, Z., He, H., Lin, J., Hoyer, K., Handschin, C., Toka, O., Ahmad, F., Matsui, T., Chin, S., Wu, P.-H., et al. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2005.03.002 · Cited by 694 · see citing works

Mitochondrial DNA mutations and human disease

Tuppen, H. A. L., Blakely, E. L., Turnbull, D. M., & Taylor, R. W. (2010) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2009.09.005 · Cited by 676 · see citing works

CNS energy metabolism as related to function

Ames, A. (2000) · Brain Research Reviews · doi:10.1016/s0165-0173(00)00038-2 · Cited by 663 · see citing works

Role of mitochondria in oxidative stress and ageing

Lenaz, G. (1998) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(98)00120-0 · Cited by 650 · see citing works

The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles

Borgstahl, G. E. O., Parge, H. E., Hickey, M. J., Beyer, W. F., Hallewell, R. A., & Tainer, J. A. (1992) · Cell · doi:10.1016/0092-8674(92)90270-m · Cited by 472 · see citing works

Mitochondrial Diabetes

Maassen, J. A., ‘t Hart, L. M., van Essen, E., Heine, R. J., Nijpels, G., Jahangir Tafrechi, R. S., Raap, A. K., Janssen, G. M. C., & Lemkes, H. H. P. J. (2004) · Diabetes · doi:10.2337/diabetes.53.2007.s103 · Cited by 439 · see citing works

DNA Polymerase γ, The Mitochondrial Replicase

Kaguni, L. S. (2004) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.72.121801.161455 · Cited by 414 · see citing works

Retrograde Ca2+ signaling in C2C12 skeletal myocytes in response to mitochondrial genetic and metabolic stress: a novel mode of inter-organelle crosstalk

Biswas, G., Adebanjo, O. A., Freedman, B. D., Anandatheerthavarada, H. K., Vijayasarathy, C., Zaidi, M., Kotlikoff, M., & Avadhani, N. G. (1999) · The EMBO Journal · doi:10.1093/emboj/18.3.522 · Cited by 369 · see citing works

Coordination of metabolic plasticity in skeletal muscle

Hood, D. A., Irrcher, I., Ljubicic, V., & Joseph, A.-M. (2006) · Journal of Experimental Biology · doi:10.1242/jeb.02182 · Cited by 370 · see citing works

Decline with age of the respiratory chain activity in human skeletal muscle

Boffoli, D., Scacco, S. C., Vergari, R., Solarino, G., Santacroce, G., & Papa, S. (1994) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/0925-4439(94)90061-2 · Cited by 341 · see citing works

DNA Polymerase γ in Mitochondrial DNA Replication and Repair

Graziewicz, M. A., Longley, M. J., & Copeland, W. C. (2006) · Chemical Reviews · doi:10.1021/cr040463d · Cited by 301 · see citing works

MtDNA mutation in MERRF syndrome causes defective aminoacylation of tRNALys and premature translation termination

Enriquez, J. A., Chomyn, A., & Attardi, G. (1995) · Nature Genetics · doi:10.1038/ng0595-47 · Cited by 285 · see citing works

The Fidelity of Human DNA Polymerase γ with and without Exonucleolytic Proofreading and the p55 Accessory Subunit

Longley, M. J., Nguyen, D., Kunkel, T. A., & Copeland, W. C. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105230200 · Cited by 270 · see citing works

Impairment of mitochondrial function in skeletal muscle of patients with amyotrophic lateral sclerosis

Wiedemann, F. R., Winkler, K., Kuznetsov, A. V., Bartels, C., Vielhaber, S., Feistner, H., & Kunz, W. S. (1998) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(98)00008-2 · Cited by 262 · see citing works

Phylogenetic analysis of Leber's hereditary optic neuropathy mitochondrial DNA's indicates multiple independent occurrences of the common mutations

Brown, M. D., Torroni, A., Reckord, C. L., & Wallace, D. C. (1995) · Human Mutation · doi:10.1002/humu.1380060405 · Cited by 256 · see citing works

Selective inhibition of mutant human mitochondrial DNA replication in vitro by peptide nucleic acids

Taylor, R. W., Chinnery, P. F., Turnbull, D. M., & Lightowlers, R. N. (1997) · Nature Genetics · doi:10.1038/ng0297-212 · Cited by 249 · see citing works

Low Reserve of Cytochrome c Oxidase Capacity in Vivo in the Respiratory Chain of a Variety of Human Cell Types

Villani, G., Greco, M., Papa, S., & Attardi, G. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.48.31829 · Cited by 225 · see citing works

Human complex I deficiency: Clinical spectrum and involvement of oxygen free radicals in the pathogenicity of the defect

Robinson, B. H. (1998) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(98)00033-4 · Cited by 223 · see citing works

Accumulation of mitochondrial DNA deletion mutations in aged muscle fibers: evidence for a causal role in muscle fiber loss

Herbst, A., Pak, J. W., McKenzie, D., Bua, E., Bassiouni, M., & Aiken, J. M. (2007) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/62.3.235 · Cited by 200 · see citing works

Tissue variation in the control of oxidative phosphorylation: Implication for mitochondrial diseases

ROSSIGNOL, R., LETELLIER, T., MALGAT, M., ROCHER, C., & MAZAT, J.-P. (2000) · Biochemical Journal · doi:10.1042/bj3470045 · Cited by 202 · see citing works

The Mitochondrial Alcohol Dehydrogenase Adh3p Is Involved in a Redox Shuttle in<i>Saccharomyces cerevisiae</i>

Bakker, B. M., Bro, C., Kötter, P., Luttik, M. A. H., van Dijken, J. P., & Pronk, J. T. (2000) · Journal of Bacteriology · doi:10.1128/jb.182.17.4730-4737.2000 · Cited by 171 · see citing works

Modification of the mitochondrial proteome in response to the stress of ethanol-dependent hepatotoxicity

Venkatraman, A., Landar, A., Davis, A. J., Chamlee, L., Sanderson, T., Kim, H., Page, G., Pompilius, M., Ballinger, S., Darley-Usmar, V., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m402245200 · Cited by 170 · see citing works

Active Site Mutation in DNA Polymerase γ Associated with Progressive External Ophthalmoplegia Causes Error-prone DNA Synthesis

Ponamarev, M. V., Longley, M. J., Nguyen, D., Kunkel, T. A., & Copeland, W. C. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.c200100200 · Cited by 156 · see citing works

Construction of transgenic mice with tissue-specific acceleration of mitochondrial DNA mutagenesis

Zhang, D., Mott, J. L., Chang, S.-W., Denniger, G., Feng, Z., & Zassenhaus, H. P. (2000) · Genomics · doi:10.1006/geno.2000.6333 · Cited by 124 · see citing works

Defect in modification at the anticodon wobble nucleotide of mitochondrial tRNA^Lys with the MERRF encephalomyopathy pathogenic mutation

Yasukawa, T., Suzuki, T., Ishii, N., Ueda, T., Ohta, S., & Watanabe, K. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)01145-5 · Cited by 124 · see citing works

Mitochondrial DNA mutations activate the mitochondrial apoptotic pathway and cause dilated cardiomyopathy

Zhang, D. (2003) · Cardiovascular Research · doi:10.1016/s0008-6363(02)00695-8 · Cited by 115 · see citing works

The effect of pre-existing maternal obesity and diabetes on placental mitochondrial content and electron transport chain activity

Hastie, R., & Lappas, M. (2014) · Placenta · doi:10.1016/j.placenta.2014.06.368 · Cited by 107 · see citing works

Exercise and training in mitochondrial myopathies

TAIVASSALO, T., & HALLER, R. G. (2005) · Medicine &amp; Science in Sports &amp; Exercise · doi:10.1249/01.mss.0000177446.97671.2a · Cited by 106 · see citing works

Search for differences in post-transcriptional modification patterns of mitochondrial DNA-encoded wild-type and mutant human tRNALys and tRNALeu(UUR)

Helm, M., Florentz, C., Chomyn, A., & Attardi, G. (1999) · Nucleic Acids Research · doi:10.1093/nar/27.3.756 · Cited by 99 · see citing works

Disorders of pyruvate carboxylase and the pyruvate dehydrogenase complex

Robinson, B. H., MacKay, N., Chun, K., & Ling, M. (1996) · Journal of Inherited Metabolic Disease · doi:10.1007/bf01799106 · Cited by 72 · see citing works

Toxicity of cuprizone a Cu²⁺chelating agent on isolated mouse brain mitochondria: a justification for demyelination and subsequent behavioral dysfunction

Faizi, M., Salimi, A., Seydi, E., Naserzadeh, P., Kouhnavard, M., Rahimi, A., & Pourahmad, J. (2016) · Toxicology Mechanisms and Methods · doi:10.3109/15376516.2016.1172284 · Cited by 71 · see citing works

Effect of the antioxidant action of Ginkgo biloba extract (EGb 761) on aging and oxidative stress

Droy-Lefaix, M. T. (1997) · AGE · doi:10.1007/s11357-997-0013-1 · Cited by 49 · see citing works

Increase in mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence

Lee, H.-C., Yin, P.-H., Chi, C.-W., & Wei, Y.-H. (2002) · Journal of Biomedical Science · doi:10.1159/000064724 · Cited by 292 · see citing works

[25] Genetics and transformation of mitochondria in the green alga Chlamydomonas

Boynton, J. E., & Gillham, N. W. (1996) · Methods in Enzymology · doi:10.1016/s0076-6879(96)64027-0 · Cited by 27 · see citing works

The Hippo–YAP pathway in organ size control and tumorigenesis: an updated versionPreprint

Zhao, B., Li, L., Lei, Q., & Guan, K. (2010) · Genes & Development · doi:10.1101/gad.1909210 · Cited by 1,140 · see citing works

Abstract IA04: Regulation of the Hippo pathway in cancer

Guan, K. (2020) · Molecular Cancer Research · doi:10.1158/1557-3125.hippo19-ia04

P04.20 The role of YAP in Glioblastoma cell lines

Casati, G., Giunti, L., Iorio, A. L., et al. (2021) · Neuro-Oncology · doi:10.1093/neuonc/noab180.074

Mechanism of Temperature Regulator and Application of Home Produced Regulator

Wang, Y.-Y., & Shanghai, S. (2006) · Pharmaceutical & Engineering Design

Hippo pathway and Bonus control developmental cell fate decisions in the Drosophila eyePreprint

Zhao, H., Moberg, K. H., & Veraksa, A. N. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.09.05.458934