The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
Invasive Infection with Saccharomyces cerevisiae: Report of Three Cases and Review
Abstract
Saccharomyces cerevisiae (brewer's or baker's yeast) is a common colonizer of human mucosal surfaces, but its role as a clinically important pathogen has been unclear. We report three cases of life-threatening invasive infection with S. cerevisiae resulting in pneumonia, liver abscess and sepsis, and disseminated infection with cardiac tamponade, respectively. A review of the English-language literature reveals 14 other cases of saccharomyces infection in humans. Severe immunosuppression, prolonged hospitalization, prior antibiotic therapy, and/or prosthetic cardiac valves are the settings where saccharomyces infection has been observed. Because Saccharomyces can be a common saprophytic contaminant, biopsy and pathologic confirmation of infection are often necessary for a definitive diagnosis. Amphotericin B is the treatment of choice for serious infections with this organism.
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“the resistance of S. cerevisiae to certain antifungal agents has been also repeatedly observed.2,26,36,38”
Citations
Cites
FUNGÆMIA AND FUNGURIA AFTER ORAL ADMINISTRATION OF CANDIDA ALBICANS
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FUNGAL ENDOCARDITIS: ANALYSIS OF 24 CASES AND REVIEW OF THE LITERATURE
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The Emerging Role of Fusarium Infections in Patients with Cancer
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Wolochow, H., Hildebrand, G. J., & Lamanna, C. (1966) · The Journal of Infectious Diseases · doi:10.1093/infdis/116.4.523 · Cited by 133
The Prevalence of Yeasts in Clinical Specimens from Cancer Patients
Kiehn, T. E., Edwards, F. F., & Armstrong, D. (1980) · American Journal of Clinical Pathology · doi:10.1093/ajcp/73.4.518 · Cited by 118
Evaluation of the modified API 20C system for identification of clinically important yeasts
Buesching, W. J., Kurek, K., & Roberts, G. D. (1979) · Journal of Clinical Microbiology · doi:10.1128/jcm.9.5.565-569.1979 · Cited by 112
Saccharomyces cerevisiaeinfections in man
Eng, R. H. K., Drehmel, R., Smith, S. M. R., & Goldstein, E. J. C. (1984) · Medical Mycology · doi:10.1080/00362178485380651 · Cited by 73
Saccharomyces cerevisiae fungemia: Case report and review of the literature
Cimolai, N., Gill, M. J., & Church, D. L. (1987) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/0732-8893(87)90158-1 · Cited by 60
Subacute and acute endocarditis due to pseudomonas cepacia in heroin addicts
Rodríguez-Noriega, E., Rubinstein, E., Simberkoff, M. S., & Rahal, J. J. (1975) · The American Journal of Medicine · doi:10.1016/0002-9343(75)90318-6 · Cited by 60
Evaluation of industrial yeasts for pathogenicity
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Cited by
Sorted by citations
Saccharomyces cerevisiae Fungemia: An Emerging Infectious Disease
Munoz, P., Bouza, E., Cuenca-Estrella, M., Eiros, J. M., Perez, M. J., Sanchez-Somolinos, M., Rincon, C., Hortal, J., & Pelaez, T. (2005) · Clinical Infectious Diseases · doi:10.1086/429916 · Cited by 462
Invasive Saccharomyces Infection: A Comprehensive Review
Enache-Angoulvant, A., & Hennequin, C. (2005) · Clinical Infectious Diseases · doi:10.1086/497832 · Cited by 369
Uncommon opportunistic fungi: new nosocomial threats
Groll, A. H., & Walsh, T. J. (2001) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2001.tb00005.x · Cited by 304
(2006) · doi:10.1007/978-3-540-28398-0 · Cited by 303
Seven cases of fungemia with Saccharomyces boulardii in critically ill patients
Lherm, T., Monet, C., Nougière, B., Soulier, M., Larbi, D., Gall, C. L., Caen, D., & Malbrunot, C. (2002) · Intensive Care Medicine · doi:10.1007/s00134-002-1267-9 · Cited by 239
Metadata
- Authors
- Aucott, J. N., Fayen, J., Grossnicklas, H., Morrissey, A., Lederman, M. M., & Salata, R. A.
- Affiliations
- Case Western Reserve University (US)
- Corresponding author
- Salata, R. A.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1990-05-01
- Volume
- 12
- Issue
- 3
- Pages
- 406-411
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2127169490
- Cited by
- 137
- References
- 15
- Citations by year
- 2026: 2 · 2025: 2 · 2023: 5 · 2022: 2 · 2021: 2 · 2020: 3 · 2019: 1 · 2018: 5 · 2017: 2 · 2016: 4 · 2015: 7 · 2014: 3 · 2013: 2 · 2012: 2
- FWCI
- 1.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Infectious Diseases (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Health Sciences › Medicine › Infectious Diseases › Fungal Infections and Studies
- Life Sciences › Immunology and Microbiology › Microbiology › Yeasts and Rust Fungi Studies
- Keywords
- Saccharomyces cerevisiae, invasive fungal infections, liver abscess, sepsis, disseminated infection, cardiac tamponade, immunosuppression, prosthetic heart valves, amphotericin B, pathogen identification
- MeSH terms
- Aged, Female, Humans, Male, Middle Aged, Mycoses, Opportunistic Infections, Saccharomyces cerevisiae
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