EpiFactors: a comprehensive database of human epigenetic factors and complexes

Cited by (307)

Items 101–200 of 307

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3. NEK6 is an injury‐responsive kinase cooperating with STAT3 in regulation of reactive astrogliosis
   Ying Yu, Tianjin Shen, Xiaoling Zhong, Lei-Lei Wang, Wenjiao Tai, Yuhua Zou, Jun Qin, Zhaohui Zhang, Chun‐Li Zhang · 2021 · Glia
4. Epigenome erosion and SOX10 drive neural crest phenotypic mimicry in triple-negative breast cancer
   J. Saunus, X. D. de Luca, Korinne S. Northwood, A. Raghavendra, A. Hasson, A. McCart Reed, M. Lim, Samir Lal, A. Vargas, J. Kutasovic et al. · 2022 · npj Breast Cancer
5. The omics era: a nexus of untapped potential for Mendelian chromatinopathies
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6. MLL1 regulates cytokine-driven cell migration and metastasis
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7. Genome-wide expert annotation of the epigenetic machinery of the plant-parasitic nematodes Meloidogyne spp., with a focus on the asexually reproducing species
   Loris Pratx, Corinne Rancurel, Martine Da Rocha, Étienne Danchin, Philippe Castagnone‐Sereno, Pierre Abad, Laetitia Perfus‐Barbeoch · 2018 · BMC Genomics
8. Transcriptome Architecture of Osteoblastic Cells Infected With Staphylococcus aureus Reveals Strong Inflammatory Responses and Signatures of Metabolic and Epigenetic Dysregulation
   Aurélie Nicolas, Martine Deplanche, Pierre‐Henri Commère, Alan Diot, Clémence Genthon, Wanderson Marques da Silva, Vasco Azevedo, Pierre Germon, Hélène Jamme, Éric Guédon et al. · 2022 · Frontiers in Cellular and Infection Microbiology
9. Systems biology and machine learning approaches identify drug targets in diabetic nephropathy
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10. Rapid profiling of transcription factor–cofactor interaction networks reveals principles of epigenetic regulation
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11. GED: a manually curated comprehensive resource for epigenetic modification of gametogenesis
    Wei-Yang Bai, Wen Yang, Wenjing Wang, Yang Wang, Can Liu, Qinghua Jiang, Jinlian Hua, Mingzhi Liao · 2016 · Briefings in Bioinformatics
12. Enhancer remodeling drives MLL oncogene-dependent transcriptional dysregulation in leukemia stem cells
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13. Comprehensive characterization of the embryonic factor LEUTX
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14. Methamphetamine-induced region-specific transcriptomic and epigenetic changes in the brain of male rats
    Benpeng Miao, Xiaoyun Xing, Viktoriia Bazylianska, Pamela A. F. Madden, Anna Moszczyńska, Bo Zhang · 2023 · Communications Biology
15. Regulation of the epigenetic landscape by immune cell oxidants
    Andrew B. Das, Annika R. Seddon, Karina M. O'Connor, Mark B. Hampton · 2021 · Free Radical Biology and Medicine
16. High temporal resolution proteome and phosphoproteome profiling of stem cell-derived hepatocyte development
    Johannes Krumm, Keisuke Sekine, Patroklos Samaras, Agnieska Brazovskaja, Markus Breunig, Ryota Yasui, Alexander Kleger, Hideki Taniguchi, Mathias Wilhelm, Barbara Treutlein et al. · 2022 · Cell Reports
17. Expanding adverse outcome pathways towards one health models for nanosafety
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18. Hypermethylation at the CXCR5 gene locus limits trafficking potential of CD8+ T cells into B-cell follicles during HIV-1 infection
    Funsho J. Ogunshola, Werner Smidt, Anneta Naidoo, Thandeka Nkosi, Thandekile Ngubane, Trevor Khaba, Omolara O. Baiyegunhi, Bongiwe Mahlobo, Sam Rasehlo, Namani Ngema et al. · 2022 · Blood Advances
19. Large-scale mapping and systematic mutagenesis of human transcriptional effector domains
    Nicole V. DelRosso, Josh Tycko, Peter Suzuki, Cecelia J. Andrews, Aradhana, Adi Xiyal Mukund, Ivan Liongson, Connor Ludwig, Kaitlyn K. Spees, Polly Morrell Fordyce et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
20. Identifying new cancer genes based on the integration of annotated gene sets via hypergraph neural networks
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21. Potential Reuse of Oncology Drugs in the Treatment of Rare Diseases
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22. Accurate detection of benign and malignant renal tumor subtypes with MethylBoostER: An epigenetic marker–driven learning framework
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23. CRdb: a comprehensive resource for deciphering chromatin regulators in human
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24. Post-transcriptional regulation of the transcriptional apparatus in neuronal development
    Mohammad Nazim · 2024 · Frontiers in Molecular Neuroscience
25. Chromatin enables precise and scalable gene regulation with factors of limited specificity
    Melinda Liu Perkins, Justin Crocker, Gašper Tkačik · 2024 · Proceedings of the National Academy of Sciences
26. TBL1 is required for the mesenchymal phenotype of transformed breast cancer cells
    Sabrina Rivero, Elena Gómez-Marín, Jose Antonio Guerrero-Martinez, Jorge García–Martínez, José C. Reyes · 2019 · Cell Death and Disease
27. Growth of Biological Complexity from Prokaryotes to Hominids Reflected in the Human Genome
    Alexander E. Vinogradov, Olga V. Anatskaya · 2021 · International Journal of Molecular Sciences
28. Monitoring transcription initiation activities in rat and dog
    Marina Lizio, Abdul Kadir Mukarram, Mizuho Ohno, Shoko Watanabe, Masayoshi Itoh, Akira Hasegawa, Timo Lassmann, Jessica Severin, Jayson Harshbarger, Imad Abugessaisa et al. · 2017 · Scientific Data
29. Leveraging epigenetic aberrations in the pathogenesis of endometriosis: from DNA methylation to non-coding RNAs
    Hajar Erraji, Adil El Ghanmi, Noureddine Louanjli, Mohamed Benahmed, Fadoua El Mansouri, Mohammed Zarqaoui, Bouchra Ghazi · 2025 · Frontiers in Genetics
30. Characterization of the genomic landscape of canine diffuse large B-cell lymphoma reveals recurrent H3K27M mutations linked to progression-free survival
    Anna Darlene van der Heiden, Raphaela Pensch, Sophie Agger, Heather L. Gardner, William P.D. Hendricks, Victoria Zismann, Shukmei Wong, Natalia Briones, Bryce Turner, Karin Forsberg‐Nilsson et al. · 2025 · Scientific Reports
31. Tracking and mitigating imprint erasure during induction of naive human pluripotency at single-cell resolution
    Laura A. Fischer, Brittany Meyer, Monica Reyes, Joseph E. Zemke, Jessica K. Harrison, Kyoung‐mi Park, Ting Wang, Harald Jüppner, Sabine Dietmann, Thorold W. Theunissen · 2025 · Stem Cell Reports
32. Global phosphoproteomic analysis identified key kinases regulating male meiosis in mouse
    Haojie Li, Hong Chen, Xiang-Zheng Zhang, Ya-Ling Qi, Bing Wang, Yiqiang Cui, Jie Ren, Yi-Chen Zhao, Yu Chen, Tianyu Zhu et al. · 2022 · Cellular and Molecular Life Sciences
33. Computational Methods for Epigenetic Drug Discovery: A Focus on Activity Landscape Modeling
    J. Jesús Naveja, Claudia Oviedo, José L. Medina‐Franco · 2018 · Advances in protein chemistry and structural biology
34. Longitudinal analysis of healthy colon establishes aspirin as a suppressor of cancer-related epigenetic aging
    Faiza Noreen, Anna Chaber-Ciopinska, Jarosław Reguła, Primo Schär, Kaspar Truninger · 2020 · Clinical Epigenetics
35. Bioinformatic identification and analysis of immune-related chromatin regulatory genes as potential biomarkers in idiopathic pulmonary fibrosis
    Kaixin Li, Pulin Liu, Wei Zhang, Xue Liu, Yoshinori Tanino, Yasuhiko Koga, Xiaoyan Yan · 2022 · Annals of Translational Medicine
36. Epigenetic regulation of human-specific gene expression in the prefrontal cortex
    Weifen Sun, Gangcai Xie, Xi Jiang, Philipp Khaitovich, Dingding Han, Xiling Liu · 2023 · BMC Biology
37. Identification and validation of chromatin regulator-related signatures as a novel prognostic model for low-grade gliomas using translational bioinformatics
    Bo Wang, Yu F, Zhengwei Li, Fan Zhou, Jie Luo, Bin Yang, Shengrong Long, Xinyi Li, Zhen‐Yuan Liu, Xiang Li et al. · 2023 · Life Sciences
38. Decoding the therapeutic landscape of alpha-linolenic acid: a network pharmacology and bioinformatics investigation against cancer-related epigenetic modifiers
    Amrita Ulhe, Nidhi Sharma, Akanksha Mahajan, Rajesh B. Patil, Mahabaleshwar Vishnu Hegde, Supriya Sudhakar Bhalerao, Aniket V. Mali · 2023 · Journal of Biomolecular Structure and Dynamics
39. Temporal and Spatial Signatures of Scylla paramamosain Transcriptome Reveal Mechanistic Insights into Endogenous Ovarian Maturation under Risk of Starvation
    Yin Fu, Fengying Zhang, Wei Wang, Jiayuan Xu, Ming Zhao, Chunyan Ma, Yongxu Cheng, Wei Chen, Zhixing Su, Xiaokang Lv et al. · 2024 · International Journal of Molecular Sciences
40. BAHD1 haploinsufficiency results in anxiety-like phenotypes in male mice
    Renaud Pourpre, Laurent Naudon, Hamid Méziane, Goran Lakisic, Luc Jouneau, Hugo Varet, Rachel Legendre, Olivia Wendling, Mohammed Selloum, Caroline Proux et al. · 2020 · PLoS ONE
41. Prognostic Significance of Dysregulated Epigenomic and Chromatin Modifiers in Cervical Cancer
    Aswathy Mary Paul, Madhavan Radhakrishna Pillai, Rakesh Kumar · 2021 · Cells
42. Defining a Correlative Transcriptional Signature Associated with Bulk Histone H3 Acetylation Levels in Adult Glioblastomas
    Irati Hervás-Corpión, Jorge Navarro-Calvo, Paula Martín-Climent, Marianela Iriarte‐Gahete, Noelia Geribaldi‐Doldán, Carmen Castro, Luis Miguel Valor · 2023 · Cells
43. MORC3 represses the HCMV major immediate early promoter in myeloid cells in the absence of PML nuclear bodies
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44. Genome-wide screening for genes involved in the epigenetic basis of fragile X syndrome
    Dan Vershkov, Atilgan Yilmaz, Ofra Yanuka, Anders Lade Nielsen, Nissim Benvenisty · 2022 · Stem Cell Reports
45. Integrative analysis of epigenetic subtypes in acute myeloid Leukemia: A multi-center study combining machine learning for prognostic and therapeutic insights
    Jincan Li, S. Wang · 2025 · PLoS ONE
46. Computational modeling reveals key molecular properties and dynamic behavior of disruptor of telomeric silencing 1‐like ( DOT1L ) and partnering complexes involved in leukemogenesis
    Timothy J. Stodola, Young‐In Chi, Thiago M. de Assuncao, Elise N. Leverence, Swarnendu Tripathi, Nikita R. Dsouza, Angela Mathison, Brian F. Volkman, Brian C. Smith, Gwen Alyce Lomberk et al. · 2021 · Proteins Structure Function and Bioinformatics
47. Developmental Brain Asymmetry. The Good and the Bad Sides
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48. A CIC-related-epigenetic factors-based model associated with prediction, the tumor microenvironment and drug sensitivity in osteosarcoma
    Bin Yu, Chengkui Geng, Zhongxiong Wu, Zhongzi Zhang, Aili Zhang, Ze Yang, Jiazheng Huang, Ying Xiong, Huiqin Yang, Zhuoyuan Chen · 2024 · Scientific Reports
49. Activation of Crtc2/Creb1 in skeletal muscle enhances weight loss during intermittent fasting
    Nelson E. Bruno, Jerome C. Nwachukwu, David C. Hughes, Sathish Srinivasan, Richard Hawkins, David Sturgill, Gordon L. Hager, Stephen Hurst, Shey‐Shing Sheu, Sue C. Bodine et al. · 2021 · The FASEB Journal
50. Mutually exclusive mutation profiles define functionally related genes in muscle invasive bladder cancer
    Ami G. Sangster, Robert J Gooding, Andrew Garven, Hamid Ghaedi, David Monty Berman, Scott K. Davey · 2022 · PLoS ONE
51. Impaired activation of Transposable Elements in SARS-CoV-2 infection
    Matan Sorek, Eran Meshorer, Sharon Schlesinger · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
52. Computational Epigenetics
    Loo Keat Wei, Anthony Au · 2017 · Elsevier eBooks
53. Coordinated neuron-specific splicing events restrict nucleosome engagement of the LSD1 histone demethylase complex
    Robert S. Porter, Sojin An, María Cecilia Gavilán, Masayoshi Nagai, Yumie Murata-Nakamura, Bo O. Zhou, Katherine M. Bonefas, Olivier Dionne, Jeru Manoj Manuel, Joannie St-Germain et al. · 2025 · Cell Reports
54. CRISPR-Cas9 knockout screen identifies novel treatment targets in childhood high-grade glioma
    Anna Wenger, Ida Karlsson, Teresia Kling, Helena Carén · 2023 · Clinical Epigenetics
55. The nuclear matrix stabilizes primed-specific genes in human pluripotent stem cells
    Gang Ma, Xiuling Fu, L.B. Zhou, Isaac A. Babarinde, Liyang Shi, Wenting Yang, Jiao Chen, Zhen Xiao, Yu Qiao, Lisha Ma et al. · 2025 · Nature Cell Biology
56. Polycystic Ovarian Syndrome: A Review of Multi-omics Analyses
    Ilmas Naqvi, Anannya Bandyopadhyay, Amisha Panda, B. Hareramadas · 2025 · Reproductive Sciences
57. GADD45G operates as a pathological sensor orchestrating reactive gliosis and neurodegeneration
    Tianjin Shen, Wenjiao Tai, Dongfang Jiang, Shuaipeng Ma, Xiaoling Zhong, Yuhua Zou, Chun‐Li Zhang · 2025 · Neuron
58. Short heat shock has a long-term effect on mesenchymal stem cells’ transcriptome
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59. GRWD1-WDR5-MLL2 Epigenetic Complex Mediates H3K4me3 Mark and Is Essential for Kaposi’s Sarcoma-Associated Herpesvirus-Induced Cellular Transformation
    Shan Wei, Songjian Lu, Lifan Liang, Xian Wang, Li Wan, Tingting Li, Luping Chen, Enguo Ju, Xinquan Zhang, Zhao Lai et al. · 2021 · mBio
60. Cooperative regulation of Zhx1 and hnRNPA1 drives the cardiac progenitor-specific transcriptional activation during cardiomyocyte differentiation
    Yang Chen, Yukang Wu, Jianguo Li, Kai Chen, Wuchan Wang, Zihui Ye, Ke Feng, Yiwei Yang, Yanxin Xu, Jiuhong Kang et al. · 2023 · Cell Death Discovery
61. Restricting epigenetic activity promotes the reprogramming of transformed cells to pluripotency in a line-specific manner
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62. A regulatory role for CHD2 in myelopoiesis
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63. Development and validation of epigenetic modification-related signals for the diagnosis and prognosis of colorectal cancer
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64. Proteomic profiling of UV damage repair patches uncovers histone chaperones with central functions in chromatin repair
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65. Native chromatome profiling reveals hundreds of metabolic enzymes in the nucleus across tissues
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66. Nuclear respiratory factor 1 transcriptomic signatures as prognostic indicators of recurring aggressive mesenchymal glioblastoma and resistance to therapy in White American females
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67. Characterization of the TBR1 interactome: variants associated with neurodevelopmental disorders disrupt novel protein interactions
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68. Phthalates impact on the epigenetic factors contributed specifically by the father at fertilization
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69. Transforming Cancer Epigenetics Using Nutritive Approaches and Noncoding RNAs
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70. Network and Evolutionary Analysis of Human Epigenetic Regulators to Unravel Disease Associations
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71. Recent advances in computational epigenetics
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72. BRD8 Guards the Pluripotent State by Sensing and Maintaining Histone Acetylation
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73. Kdm4a is an activity downregulated barrier to generate engrams for memory separation
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74. Polyploidy Promotes Hypertranscription, Apoptosis Resistance, and Ciliogenesis in Cancer Cells and Mesenchymal Stem Cells of Various Origins: Comparative Transcriptome In Silico Study
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75. The role of TCF3 as potential master regulator in blastemal Wilms tumors
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76. TBX21 Methylation as a Potential Regulator of Immune Suppression in CMS1 Subtype Colorectal Cancer
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77. Seven chromatin regulators as immune cell infiltration characteristics, potential diagnostic biomarkers and drugs prediction in hepatocellular carcinoma
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78. STRN3 promotes tumour growth in hepatocellular carcinoma by inhibiting the hippo pathway
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79. ENO1 as a Biomarker of Breast Cancer Progression and Metastasis: A Bioinformatic Approach Using Available Databases
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80. Development and pan-cancer validation of an epigenetics-based random survival forest model for prognosis prediction and drug response in OS
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81. Databases and prospects of dynamic gene regulation in eukaryotes: A mini review
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82. The chromatin remodeling factors EP300 and TRRAP are novel SMYD3 interactors involved in the emerging ‘nonmutational epigenetic reprogramming’ cancer hallmark
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83. Chromatin regulator SMARCAL1 modulates cellular lipid metabolism
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84. Key chromatin regulator-related genes associated with the risk of coronary artery disease regulate the expression of HCFC1, RNF8, TNP1 and SET
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85. Genome-wide profiling of an enhancer-associated histone modification reveals the influence of asthma on the epigenome of the airway epithelium
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86. A modular dCas9-based recruitment platform for combinatorial epigenome editing
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87. Unraveling the cohesin-chromatin interface: identifying protein interactions that modulate chromosome structure and function
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88. Zbtb16 determines the fate plasticity of cardiovascular progenitors through IGF2BP3-mediated mRNA stabilization
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89. KMT2D loss drives adeno-to-squamous transition and sensitizes TKI-resistant lung cancer to AURKA inhibition
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90. The Role of Long Noncoding RNAs in Plants
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91. Multiplexed perturbation enables scalable pooled screens
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92. ARN: Analysis and Visualization System for Adipogenic Regulation Network Information
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93. An effective prognostic model in colon adenocarcinoma composed of cuproptosis-related epigenetic regulators
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94. Construction and validation of a chromatin regulator-related gene signature for prognostic and therapeutic significance of clear cell renal cell carcinoma
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95. ASXL1 truncating variants in BOS and myeloid leukemia drive shared disruption of Wnt-signaling pathways but have differential isoform usage of RUNX3
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96. Enhanced identification of significant regulators of gene expression
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97. B-CAN: a resource sharing platform to improve the operation, visualization and integrated analysis of TCGA breast cancer data
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98. Characterization of chromatin regulators identified prognosis and heterogeneity in hepatocellular carcinoma
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99. CREWdb 1.0: Optimizing Chromatin Readers, Erasers, and Writers Database using Machine Learning-Based Approach
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100. DNA methylation aberrancy is a reliable prognostic tool in uveal melanoma
     Andrea Šoltýsová, Dana Dvorská, Viera Horváthová Kajabová, Martina Pecimonova, Klaudia Cepcekova, Andrej Ficek, Lucia Demková, Verona Buociková, Pavel Babál, Ivan Juras et al. · 2023 · Research Square