EpiFactors: a comprehensive database of human epigenetic factors and complexes

An integrated encyclopedia of DNA elements in the human genome

The ENCODE Project Consortium (2012) · Nature · doi:10.1038/nature11247 · Cited by 18,072 · see citing works

Translating the Histone Code

Jenuwein, T., & Allis, C. D. (2001) · Science · doi:10.1126/science.1063127 · Cited by 9,756 · see citing works

Crystal structure of the nucleosome core particle at 2.8 Å resolution

Luger, K., Mäder, A. W., Richmond, R. K., Sargent, D. F., & Richmond, T. J. (1997) · Nature · doi:10.1038/38444 · Cited by 9,466 · see citing works

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

The Cancer Genome Atlas Research Network (2008) · Nature · doi:10.1038/nature07385 · Cited by 7,735 · see citing works

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

Jaenisch, R., & Bird, A. (2003) · Nature Genetics · doi:10.1038/ng1089 · Cited by 6,325 · see citing works

Regulation of chromatin by histone modifications

Bannister, A. J., & Kouzarides, T. (2011) · Cell Research · doi:10.1038/cr.2011.22 · Cited by 6,012 · see citing works

Lanthanum Chloride Inhibits LPS Mediated Expressions of Pro-Inflammatory Cytokines and Adhesion Molecules in HUVECs: Involvement of NF-κB-Jmjd3 Signaling

Chen, X., Xiu, M., Xing, J., Yu, S., Min, D., & Guo, F. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000479439 · Cited by 5,759 · see citing works

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

Li, E., Bestor, T. H., & Jaenisch, R. (1992) · Cell · doi:10.1016/0092-8674(92)90611-f · Cited by 3,984 · see citing works

From molecular to modular cell biology.

Hartwell, L. H., Hopfield, J. J., Leibler, S., & Murray, A. W. (1999) · Nature · doi:10.1038/35011540 · Cited by 3,632 · see citing works

Environmental epigenomics and disease susceptibility

Jirtle, R. L., & Skinner, M. K. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2045 · Cited by 2,492 · see citing works

Histone demethylation by a family of JmjC domain-containing proteins

Tsukada, Y.-I., Fang, J., Erdjument‐Bromage, H., Warren, M., Borchers, C. H., Tempst, P., & Zhang, Y. (2005) · Nature · doi:10.1038/nature04433 · Cited by 2,171 · see citing works

The Role of DNA Methylation in Mammalian Epigenetics

Jones, P. A., & Takai, D. (2001) · Science · doi:10.1126/science.1063852 · Cited by 2,063 · see citing works

Function and information content of DNA methylation

Schübeler, D. (2015) · Nature · doi:10.1038/nature14192 · Cited by 2,060 · see citing works

A promoter-level mammalian expression atlas

The FANTOM Consortium and the RIKEN PMI and CLST (DGT) (2014) · Nature · doi:10.1038/nature13182 · Cited by 1,982 · see citing works

The MIntAct project—IntAct as a common curation platform for 11 molecular interaction databases

Orchard, S. E., Ammari, M. G., Aranda, B., Breuza, L., Briganti, L., Broackes-Carter, F. C., Campbell, N. H., Chavali, G. B., Chen, C. C. L., del‐Toro, N., et al. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt1115 · Cited by 1,835 · see citing works

TET enzymes, TDG and the dynamics of DNA demethylation

Kohli, R. M., & Zhang, Y. (2013) · Nature · doi:10.1038/nature12750 · Cited by 1,623 · see citing works

Covalent Modification of DNA Regulates Memory Formation

Miller, C. A., & Sweatt, J. D. (2007) · Neuron · doi:10.1016/j.neuron.2007.02.022 · Cited by 1,180 · see citing works

New nomenclature for chromatin-modifying enzymes

Allis, C. D., Berger, S. L., Cote, J., Dent, S., Jenuwien, T., Kouzarides, T., Pillus, L., Reinberg, D., Shi, Y., Shiekhattar, R., et al. (2007) · Cell · doi:10.1016/j.cell.2007.10.039 · Cited by 957 · see citing works

PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes

Gao, Z., Zhang, J., Bonasio, R., Strino, F., Sawai, A., Parisi, F., Kluger, Y., & Reinberg, D. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.01.002 · Cited by 852 · see citing works

The SET-domain protein superfamily: protein lysine methyltransferases.

Dillon, S. C., Zhang, X. Y., Trievel, R. C., & Cheng, X. (2005) · Genome biology · doi:10.1186/gb-2005-6-8-227 · Cited by 784 · see citing works

The protamine family of sperm nuclear proteins

Balhorn, R. (2007) · Genome biology · doi:10.1186/gb-2007-8-9-227 · Cited by 776 · see citing works

Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domainsPreprint

Rakyan, V. K., Down, T. A., Maslau, S., Andrew, T., Yang, T.-P., Beyan, H., Whittaker, P., McCann, O. T., Finer, S., Valdes, A. M., et al. (2010) · Genome Research · doi:10.1101/gr.103101.109 · Cited by 750 · see citing works

Readers of histone modifications

Yun, M., Wu, J., Workman, J. L., & Li, B. (2011) · Cell Research · doi:10.1038/cr.2011.42 · Cited by 626 · see citing works

Crosstalk between histone modifications during the DNA damage response

van Attikum, H., & Gasser, S. M. (2009) · Trends in Cell Biology · doi:10.1016/j.tcb.2009.03.001 · Cited by 515 · see citing works

Trithorax group proteins: switching genes on and keeping them active

Schuettengruber, B., Martinez, A., Iovino, N., & Cavalli, G. (2011) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3230 · Cited by 454 · see citing works

Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer

Plass, C., Pfister, S. M., Lindroth, A. M., Bogatyrova, O., Claus, R., & Lichter, P. (2013) · Nature Reviews Genetics · doi:10.1038/nrg3554 · Cited by 448 · see citing works

Chromatin proteins and modifications as drug targets

Helin, K., & Dhanak, D. (2013) · Nature · doi:10.1038/nature12751 · Cited by 435 · see citing works

Identification of genetic elements that autonomously determine DNA methylation states

Lienert, F., Wirbelauer, C., Som, I., Dean, A., Mohn, F., & Schübeler, D. (2011) · Nature Genetics · doi:10.1038/ng.946 · Cited by 385 · see citing works

Histone chaperones in nucleosome assembly and human disease

Burgess, R. J., & Zhang, Z. (2013) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2461 · Cited by 383 · see citing works

Chromatin remodelling in mammalian differentiation: lessons from ATP-dependent remodellers

de la Serna, I. L., Ohkawa, Y., & Imbalzano, A. N. (2006) · Nature Reviews Genetics · doi:10.1038/nrg1882 · Cited by 376 · see citing works

Chromatin repressive complexes in stem cells, development, and cancer

Laugesen, A., & Helin, K. (2014) · Cell stem cell · doi:10.1016/j.stem.2014.05.006 · Cited by 352 · see citing works

MethHC: a database of DNA methylation and gene expression in human cancer

Huang, W.-Y., Hsu, S., Huang, H., Sun, Y.-M., Chou, C., Weng, S.-L., & Huang, H. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku1151 · Cited by 296 · see citing works

Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cellsPreprint

Clouaire, T., Webb, S., Skene, P., Illingworth, R. S., Kerr, A. R. W., Andrews, R., Lee, J., Skalnik, D. G., & Bird, A. P. (2012) · Genes & Development · doi:10.1101/gad.194209.112 · Cited by 273 · see citing works

Effects of cytosine methylation on transcription factor binding sites

Medvedeva, Y., Khamis, A. M., Kulakovskiy, I., Ba-alawi, W., Bhuyan, M. S., Kawaji, H., Lassmann, T., Harbers, M., Forrest, A., & Bajic, V. (2014) · BMC Genomics · doi:10.1186/1471-2164-15-119 · Cited by 253 · see citing works

HOCOMOCO: a comprehensive collection of human transcription factor binding sites models

Kulakovskiy, I. V., Medvedeva, Y. A., Schaefer, U., Kasianov, A. S., Vorontsov, I. E., Bajić, V. B., & Makeev, V. J. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks1089 · Cited by 230 · see citing works

X inactivation and the complexities of silencing a sex chromosome

Chow, J., & Heard, É. (2009) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2009.04.012 · Cited by 212 · see citing works

The NIH Roadmap Epigenomics Program data Resource

Chadwick, L. H. (2012) · Epigenomics · doi:10.2217/epi.12.18 · Cited by 200 · see citing works

MethyCancer: the database of human DNA methylation and cancer

He, X., Chang, S., Zhang, J., Zhao, Q. P., Xiang, H., Kusonmano, K., Yang, L., Sun, Z. S., Yang, H., & Wang, J. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm730 · Cited by 141 · see citing works

Cancer Epigenetics and Methylation

Esteller, M., Fraga, M. F., Paz, M. F., Campo, E., Colomer, D., Novo, F. J., Calasanz, M. J., Galm, O., Guo, M., Benitez, J. J., et al. (2002) · Science · doi:10.1126/science.297.5588.1807d · Cited by 135 · see citing works

HIstome--a relational knowledgebase of human histone proteins and histone modifying enzymes

Khare, S., Habib, F., Sharma, R., Gadewal, N. S., Gupta, S., & Galande, S. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr1125 · Cited by 133 · see citing works

Epigenetics: The missing link to understanding β-cell dysfunction in the pathogenesis of type 2 diabetes

Gilbert, E. R., & Liu, D. (2012) · Epigenetics · doi:10.4161/epi.21238 · Cited by 120 · see citing works

Role of Epigenetics in Alzheimer ‘S and Parkinson‘S Disease

Kwok, J. B. (2010) · Epigenomics · doi:10.2217/epi.10.43 · Cited by 119 · see citing works

MBD family proteins: reading the epigenetic code

Fatemi, M., & Wade, P. A. (2006) · Journal of Cell Science · doi:10.1242/jcs.03099 · Cited by 117 · see citing works

Genome-wide conserved consensus transcription factor binding motifs are hyper-methylated

Choy, M., Movassagh, M., Goh, H. G., Bennett, M. R., Down, T. A., & Foo, R. (2010) · BMC Genomics · doi:10.1186/1471-2164-11-519 · Cited by 115 · see citing works

Chromatin regulation: How complex does it get?

Meier, K., & Brehm, A. (2014) · Epigenetics · doi:10.4161/15592294.2014.971580 · Cited by 114 · see citing works

The complex portal - an encyclopaedia of macromolecular complexes

Meldal, B., Forner, O., Costanzo, M. C., Dana, J. M., Demeter, J., Dumousseau, M., Dwight, S. S., Gaulton, A., Licata, L., Melidoni, A. N., et al. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku975 · Cited by 114 · see citing works

MethDB--a public database for DNA methylation data

Grunau, C. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.1.270 · Cited by 110 · see citing works

Predicting nucleosome positions on the DNA: combining intrinsic sequence preferences and remodeler activities

Teif, V. B., & Rippe, K. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp610 · Cited by 99 · see citing works

HHMD: the human histone modification database

Zhang, Y., Lv, J., Liu, H., Zhu, J., Su, J., Wu, Q., Qi, Y., Wang, F., & Li, X. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp968 · Cited by 91 · see citing works

ChromDB: The Chromatin Database

Gendler, K., Paulsen, T., & Napoli, C. A. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm768 · Cited by 89 · see citing works

Promoter Analysis Reveals Globally Differential Regulation of Human Long Non-Coding RNA and Protein-Coding Genes

Alam, T., Medvedeva, Y. A., Jia, H., Brown, J., Lipovich, L., & Bajić, V. B. (2014) · PLoS ONE · doi:10.1371/journal.pone.0109443 · Cited by 78 · see citing works

Dynamic Interplay between Histone H3 Modifications and Protein Interpreters: Emerging Evidence for a “Histone Language”

Oliver, S. S., & Denu, J. M. (2010) · ChemBioChem · doi:10.1002/cbic.201000474 · Cited by 76 · see citing works

Histone modifications: crucial elements for damage response and chromatin restoration

Zhu, Q., & Wani, A. A. (2010) · Journal of Cellular Physiology · doi:10.1002/jcp.22060 · Cited by 72 · see citing works

NCBI Epigenomics: a new public resource for exploring epigenomic data sets

Fingerman, I. M., McDaniel, L., Zhang, X., Ratzat, W., Hassan, T., Jiang, Z., Cohen, R. F., & Schuler, G. D. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq1146 · Cited by 66 · see citing works

NGSmethDB: a database for next-generation sequencing single-cytosine-resolution DNA methylation data

Hackenberg, M., Barturen, G., & Oliver, J. L. T. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq942 · Cited by 55 · see citing works

An improved version of the DNA methylation database (MethDB)

Amoreira, C. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg093 · Cited by 54 · see citing works

The Histone Database: an integrated resource for histones and histone fold-containing proteins

Mariño‐Ramírez, L., Levine, K. M., Morales, M. R. G., Zhang, S., Moreland, R. T., Baxevanis, A. D., & Landsman, D. (2011) · Database · doi:10.1093/database/bar048 · Cited by 50 · see citing works

CR Cistrome: a ChIP-Seq database for chromatin regulators and histone modification linkages in human and mouse

Wang, Q., Huang, J., Sun, H., Liu, J., Wang, J., Wang, Q., Qin, Q., Mei, S., Zhao, C., Yang, X., et al. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt1151 · Cited by 49 · see citing works

MethBank: a database integrating next-generation sequencing single-base-resolution DNA methylation programming data

Zou, D., Sun, S., Li, R., Liu, J., Zhang, J., & Zhang, Z. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku920 · Cited by 35 · see citing works

Regional differences in gene expression and promoter usage in aged human brains

Pardo, L. M., Rizzu, P., Francescatto, M., Vitezic, M., Leday, G. G. R., Sanchez, J. S., Khamis, A. M., Takahashi, H., van de Berg, W. D. J., Medvedeva, Y. A., et al. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2013.01.005 · Cited by 34 · see citing works

Extensive Transcriptional Regulation of Chromatin Modifiers during Human Neurodevelopment

Weng, M. K., Zimmer, B., Pöltl, D., Broeg, M. P., Ivanova, V. N., Gaspar, J. A., Sachinidis, A., Wüllner, U., Waldmann, T., & Leist, M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0036708 · Cited by 33 · see citing works

NCBI Epigenomics: What’s new for 2013

Fingerman, I. M., Zhang, X., Ratzat, W., Husain, N., Cohen, R. F., & Schuler, G. D. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks1171 · Cited by 29 · see citing works

CREMOFAC—a database of chromatin remodeling factors

Agrawal, S., Chetan, K., & Rao, M. R. S. (2006) · Bioinformatics · doi:10.1093/bioinformatics/btl509 · Cited by 22 · see citing works

PEpiD: A Prostate Epigenetic Database in Mammals

Shi, J., Hu, J. M., Zhou, Q., Du, Y., & Jiang, C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0064289 · Cited by 13 · see citing works

Epigenetic Regulation of Pluripotency

Tomazou, E. M., & Meissner, A. (2010) · Advances in experimental medicine and biology · doi:10.1007/978-1-4419-7037-4_3 · Cited by 9 · see citing works

Toward a New Human Species?

Spier, R. E. (2002) · Science · doi:10.1126/science.1072667 · Cited by 7 · see citing works

EPITRANS: A Database that Integrates Epigenome and Transcriptome Data

Cho, S. Y., Chai, J. C., Park, S. J., Seo, H., Sohn, C.-B., & Lee, Y. S. (2013) · Molecules and Cells · doi:10.1007/s10059-013-0249-9 · Cited by 7 · see citing works

TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion

Khan, O., Giles, J. R., McDonald, S., Manne, S., Ngiow, S. F., Patel, K. P., Werner, M. T., Huang, A. C., Alexander, K. A., Wu, J. E., et al. (2019) · Nature · doi:10.1038/s41586-019-1325-x · Cited by 1,646 · see citing works

Chromatin Accessibility Dynamics during iPSC Reprogramming

Li, D., Liu, J., Yang, X., Zhou, C., Guo, J., Wu, C., Qin, Y., Guo, L., He, J., Yu, S., et al. (2017) · Cell Stem Cell · doi:10.1016/j.stem.2017.10.012 · Cited by 251 · see citing works

Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis

Argemí, J., Latasa, M. U., Atkinson, S. R., Blokhin, I. O., Massey, V. L., Gue, J. P., Cabezas, J., Lozano, J. J., Booven, D. V., Bell, A. W., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-11004-3 · Cited by 195 · see citing works

Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction

Bhattacherjee, A., Djekidel, M. N., Chen, R., Chen, W., Tuesta, L. M., & Zhang, Y. (2019) · Nature Communications · doi:10.1038/s41467-019-12054-3 · Cited by 174 · see citing works

Epigenetic remodelling licences adult cholangiocytes for organoid formation and liver regeneration

Aloia, L., McKie, M. A., Vernaz, G., Cordero-Espinoza, L., Aleksieva, N., van den Ameele, J., Antonica, F., Font-Cunill, B., Raven, A., Aiese Cigliano, R., et al. (2019) · Nature Cell Biology · doi:10.1038/s41556-019-0402-6 · Cited by 160 · see citing works

Transposable elements are regulated by context-specific patterns of chromatin marks in mouse embryonic stem cells

He, J., Fu, X., Zhang, M., He, F., Li, W., Abdul, M. M., Zhou, J., Sun, L., Chang, C., Li, Y., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-08006-y · Cited by 141 · see citing works

Large-scale mapping and mutagenesis of human transcriptional effector domains

DelRosso, N., Tycko, J., Suzuki, P., Andrews, C., Aradhana, Mukund, A., Liongson, I., Ludwig, C., Spees, K., Fordyce, P., et al. (2023) · Nature · doi:10.1038/s41586-023-05906-y · Cited by 130 · see citing works

In silico cancer research towards 3R

Jean-Quartier, C., Jeanquartier, F., Jurišica, I., & Holzinger, A. (2018) · BMC Cancer · doi:10.1186/s12885-018-4302-0 · Cited by 126 · see citing works

Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers

Klomp, J. A., Klomp, J. E., Stalnecker, C. A., Bryant, K. L., Edwards, A. C., Drizyte‐Miller, K., Hibshman, P. S., Diehl, J. N., Lee, Y. S., Morales, A. J., et al. (2024) · Science · doi:10.1126/science.adk0775 · Cited by 133 · see citing works

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Buljan, M., Ciuffa, R., van Drogen, A., Vichalkovski, A., Mehnert, M., Rosenberger, G., Lee, S., Varjosalo, M. T., Pernas, L. E., Spegg, V., et al. (2020) · Molecular Cell · doi:10.1016/j.molcel.2020.07.001 · Cited by 115 · see citing works

Update of the FANTOM web resource: high resolution transcriptome of diverse cell types in mammals

Lizio, M., Harshbarger, J., Abugessaisa, I., Noguchi, S., Kondo, A., Severin, J., Mungall, C., Arenillas, D. J., Mathelier, A., Medvedeva, Y. A., et al. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw995 · Cited by 115 · see citing works

Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer

Yomtoubian, S., Lee, S. B., Verma, A., Izzo, F., Markowitz, G. J., Choi, H., Cerchietti, L. C. A., Vahdat, L. T., Brown, K. A., Andreopoulou, E., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2019.12.056 · Cited by 111 · see citing works

FACER: comprehensive molecular and functional characterization of epigenetic chromatin regulators

Lu, J., Xu, J., Li, J., Pan, T., Bai, J., Wang, L., Jin, X., Li, X., Zhang, Y., Li, Y., et al. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky679 · Cited by 107 · see citing works

Profiling the genetic determinants of chromatin accessibility with scalable single-cell CRISPR screens

Liscovitch-Brauer, N., Montalbano, A., Deng, J., Méndez-Mancilla, A., Wessels, H.-H., Moss, N. G., Kung, C.-Y., Sookdeo, A., Guo, X., Geller, E., et al. (2021) · Nature Biotechnology · doi:10.1038/s41587-021-00902-x · Cited by 107 · see citing works

A Sustained Immune Response Supports Long-Term Antiviral Immune Priming in the Pacific Oyster, Crassostrea gigas

Lafont, M., Vergnes, A., Vidal‐Dupiol, J., de Lorgeril, J., Gueguen, Y., Haffner, P., Petton, B., Chaparro, C., Barrachina, C., Destoumieux‐Garzón, D., et al. (2020) · mBio · doi:10.1128/mbio.02777-19 · Cited by 97 · see citing works

Lung transcriptome of a COVID-19 patient and systems biology predictions suggest impaired surfactant production which may be druggable by surfactant therapy

Islam, A. B. M. M. K., & Khan, M. A. (2020) · Scientific Reports · doi:10.1038/s41598-020-76404-8 · Cited by 91 · see citing works

Determining the ERK-regulated phosphoproteome driving KRAS-mutant cancer

Klomp, J. E., Diehl, J. N., Klomp, J. A., Edwards, A. C., Yang, R., Morales, A. J., Taylor, K. E., Drizyte-Miller, K., Bryant, K. L., Schaefer, A., et al. (2024) · Science · doi:10.1126/science.adk0850 · Cited by 83 · see citing works

Twin DNA Methylation Profiling Reveals Flare‐Dependent Interferon Signature and B Cell Promoter Hypermethylation in Systemic Lupus Erythematosus

Ulff-Møller, C. J., Asmar, F., Liu, Y., Svendsen, A. J., Busato, F., Grønbæk, K., Tost, J., & Jacobsen, S. (2018) · Arthritis & Rheumatology · doi:10.1002/art.40422 · Cited by 94 · see citing works

Computer-aided biomarker discovery for precision medicine: data resources, models and applications

Lin, Y., Qian, F., Shen, L., Chen, F., Chen, J., & Shen, B. (2017) · Briefings in Bioinformatics · doi:10.1093/bib/bbx158 · Cited by 91 · see citing works

Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas

Wang, H., Bender, A. S., Wang, P., Karaköse, E., Inabnet, W. B., Libutti, S. K., Arnold, A., Lambertini, L., Stang, M., Chen, H., et al. (2017) · Nature Communications · doi:10.1038/s41467-017-00992-9 · Cited by 83 · see citing works

Neuron-specific alternative splicing of transcriptional machineries: Implications for neurodevelopmental disorders

Porter, R. S., Jaamour, F., & Iwase, S. (2017) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2017.10.006 · Cited by 80 · see citing works

Heterochromatin Protein 1α Mediates Development and Aggressiveness of Neuroendocrine Prostate Cancer

Ci, X., Hao, J., Dong, X., Choi, S. Y. C., Xue, H., Wu, R., Qu, S., Gout, P. W., Zhang, F., Haegert, A. M., et al. (2018) · Cancer Research · doi:10.1158/0008-5472.can-17-3677 · Cited by 80 · see citing works

FusionGDB: fusion gene annotation DataBase

Kim, P., & Zhou, X. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky1067 · Cited by 80 · see citing works

Intrinsic transcriptomic sex differences in human endothelial cells at birth and in adults are associated with coronary artery disease targets

Hartman, R. J. G., Kapteijn, D., Haitjema, S., Bekker, M. N., Mokrý, M., Pasterkamp, G., Civelek, M., & den Ruijter, H. M. (2020) · Scientific Reports · doi:10.1038/s41598-020-69451-8 · Cited by 79 · see citing works

p113 isoform encoded by CUX1 circular RNA drives tumor progression via facilitating ZRF1/BRD4 transactivation

Yang, F., Hu, A., Guo, Y., Wang, J., Li, D., Wang, X., Jin, S., Yuan, B., Cai, S., Zhou, Y., et al. (2021) · Molecular Cancer · doi:10.1186/s12943-021-01421-8 · Cited by 79 · see citing works

Methionine metabolism controls the B cell EBV epigenome and viral latency

Guo, R., Liang, J. H., Zhang, Y., Lutchenkov, M., Li, Z., Wang, Y., Trujillo-Alonso, V., Puri, R., Giulino-Roth, L. G., & Gewurz, B. E. (2022) · Cell Metabolism · doi:10.1016/j.cmet.2022.08.008 · Cited by 76 · see citing works

EpiFactors 2022: expansion and enhancement of a curated database of human epigenetic factors and complexes

Marakulina, D., Vorontsov, I. E., Kulakovskiy, I. V., Lennartsson, A., Drabløs, F., & Medvedeva, Y. A. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkac989 · Cited by 78 · see citing works

Landscape of mSWI/SNF chromatin remodeling complex perturbations in neurodevelopmental disorders

Valencia, A. M., Sankar, A., van der Sluijs, P. J., Satterstrom, F. K., Fu, J. M., Talkowski, M. E., Vergano, S. A. S., Santen, G. W. E., & Kadoch, C. (2023) · Nature Genetics · doi:10.1038/s41588-023-01451-6 · Cited by 77 · see citing works

Decoding chromatin states by proteomic profiling of nucleosome readers

Lukauskas, S., Tvardovskiy, A., Nguyen, N. V., Stadler, M., Faull, P. A., Ravnsborg, T., Aygenli, B. Ö., Dornauer, S., Flynn, H. R., Lindeboom, R. G. H., et al. (2024) · Nature · doi:10.1038/s41586-024-07141-5 · Cited by 75 · see citing works

Epigenomic signatures reveal mechanistic clues and predictive markers for autism spectrum disorder

LaSalle, J. M. (2023) · Molecular Psychiatry · doi:10.1038/s41380-022-01917-9 · Cited by 79 · see citing works

Transcription profiling of peripheral B cells in antibody‐positive primary Sjögren's syndrome reveals upregulated expression of CX3CR1 and a type I and type II interferon signature

Imgenberg‐Kreuz, J., Sandling, J. K., Björk, A., Nordlund, J., Kvarnström, M., Eloranta, M., Rönnblom, L., Wahren‐Herlenius, M., Syvänen, A., & Nordmark, G. (2018) · Scandinavian Journal of Immunology · doi:10.1111/sji.12662 · Cited by 68 · see citing works

A multicenter analysis of genomic profiles and PD-L1 expression of primary lymphoepithelioma-like carcinoma of the lung

Xie, Z., Liu, L., Lin, X., Xie, X., Gu, Y., Liu, M., Zhang, J., Ouyang, M., Lizaso, A., Zhang, H., et al. (2019) · Modern Pathology · doi:10.1038/s41379-019-0391-9 · Cited by 67 · see citing works

Targeting p53 and histone methyltransferases restores exhausted CD8+ T cells in HCV infection

Barili, V., Fisicaro, P., Montanini, B., Acerbi, G., Filippi, A., Forleo, G., Romualdi, C., Ferracin, M., Guerrieri, F., Pedrazzi, G., et al. (2020) · Nature Communications · doi:10.1038/s41467-019-14137-7 · Cited by 67 · see citing works

Recurrent loss of heterozygosity correlates with clinical outcome in pancreatic neuroendocrine cancer

Lawrence, B. J., Blenkiron, C., Parker, K., Tsai, P., Fitzgerald, S. J., Shields, P., Robb, T. J., Yeong, M. L., Kramer, N., James, S., et al. (2018) · npj Genomic Medicine · doi:10.1038/s41525-018-0058-3 · Cited by 65 · see citing works

Gene expression profiling of epigenetic chromatin modification enzymes and histone marks by cigarette smoke: implications for COPD and lung cancer

Sundar, I. K., & Rahman, I. (2016) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00253.2016 · Cited by 64 · see citing works

DORGE: Discovery of Oncogenes and tumoR suppressor genes using Genetic and Epigenetic features

Lyu, J., Li, J. J., Su, J., Peng, F., Chen, Y. E., Ge, X., & Li, W. (2020) · Science Advances · doi:10.1126/sciadv.aba6784 · Cited by 60 · see citing works

Epigenetic modifications acetylation and deacetylation play important roles in juvenile hormone action

Roy, A., & Palli, S. R. (2018) · BMC Genomics · doi:10.1186/s12864-018-5323-4 · Cited by 63 · see citing works

FusionGDB 2.0: fusion gene annotation updates aided by deep learning

Kim, P., Tan, H., Liu, J., Lee, H., Jung, H., Kumar, H., & Zhou, X. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab1056 · Cited by 61 · see citing works

Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes

Yi, G., Wierenga, A. T. J., Petraglia, F., Narang, P., Janssen‐Megens, E. M., Mandoli, A., Merkel, A., Berentsen, K., Kim, B., Matarese, F., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2018.12.098 · Cited by 60 · see citing works

LncRNA regulation: New frontiers in epigenetic solutions to drug chemoresistance

Zhou, Y., Sun, W. C., Qin, Z., Guo, S., Kang, Y., Zeng, S., & Yu, L. (2020) · Biochemical Pharmacology · doi:10.1016/j.bcp.2020.114228 · Cited by 58 · see citing works

Development of compact transcriptional effectors using high-throughput measurements in diverse contexts

Tycko, J., Van, M. V., Aradhana, DelRosso, N., Ye, H., Yao, D., Valbuena, R., Vaughan-Jackson, A., Xu, X., Ludwig, C., et al. (2025) · Nature Biotechnology · doi:10.1038/s41587-024-02442-6 · Cited by 57 · see citing works

Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks

Mallm, J., Iskar, M., Ishaque, N., Klett, L. C., Kugler, S. J., Muiño, J. M., Teif, V. B., Poos, A. M., Großmann, S., Erdel, F., et al. (2019) · Molecular Systems Biology · doi:10.15252/msb.20188339 · Cited by 55 · see citing works

Computational methods and next-generation sequencing approaches to analyze epigenetics data: Profiling of methods and applications

Arora, I., & Tollefsbol, T. O. (2020) · Methods · doi:10.1016/j.ymeth.2020.09.008 · Cited by 56 · see citing works

Recent progress on cheminformatics approaches to epigenetic drug discovery

Sessions, Z. L., Sánchez‐Cruz, N., Prieto-Martínez, F. D., Alves, V. M., Junior, H. P. D. O. S., Muratov, E. N., Tropsha, A., & Medina‐Franco, J. L. (2020) · Drug Discovery Today · doi:10.1016/j.drudis.2020.09.021 · Cited by 54 · see citing works

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1

Elsen, G. E., Bedogni, F., Hodge, R. D., Bammler, T. K., MacDonald, J. W., Lindtner, S., Rubenstein, J. L. R., & Hevner, R. F. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00571 · Cited by 56 · see citing works

Clinical significance of miRNA host gene promoter methylation in prostate cancer

Daniūnaitė, K., Dubikaityte, M., Gibas, P., Bakavičius, A., Lazutka, J. R., Ulys, A., Jankevičius, F., & Jarmalaitė, S. (2017) · Human Molecular Genetics · doi:10.1093/hmg/ddx138 · Cited by 54 · see citing works

Coexpression patterns define epigenetic regulators associated with neurological dysfunctionPreprint

Boukas, L., Havrilla, J. M., Hickey, P. F., Quinlan, A. R., Bjornsson, H. T., & Hansen, K. D. (2019) · Genome Research · doi:10.1101/gr.239442.118 · Cited by 51 · see citing works

A polyphenol-rich green Mediterranean diet enhances epigenetic regulatory potential: the DIRECT PLUS randomized controlled trial

Hoffmann, A., Meir, A. Y., Hagemann, T., Czechowski, P., Müller, L., Engelmann, B., Haange, S., Rolle-Kampczyk, U. E., Tsaban, G., Zelicha, H., et al. (2023) · Metabolism · doi:10.1016/j.metabol.2023.155594 · Cited by 52 · see citing works

Comparative transcriptome analysis reveals key epigenetic targets in SARS-CoV-2 infection

Salgado-Albarrán, M., Navarro-Delgado, E. I., Moral-Morales, A. D., Alcaraz, N., Baumbach, J., González-Barrios, R., & Soto‐Reyes, E. (2021) · npj Systems Biology and Applications · doi:10.1038/s41540-021-00181-x · Cited by 51 · see citing works

CpG traffic lights are markers of regulatory regions in human genome

Lioznova, A. V., Khamis, A. M., Artemov, A. V., Besedina, E. G., Ramensky, V. E., Bajić, V. B., Kulakovskiy, I. V., & Medvedeva, Y. A. (2019) · BMC Genomics · doi:10.1186/s12864-018-5387-1 · Cited by 43 · see citing works

SARS-CoV-2 Proteins Exploit Host’s Genetic and Epigenetic Mediators for the Annexation of Key Host Signaling Pathways

Khan, M. A., & Islam, A. B. M. M. K. (2021) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2020.598583 · Cited by 44 · see citing works

Enhancer Remodeling and MicroRNA Alterations Are Associated with Acquired Resistance to ALK Inhibitors

Yun, M. R., Lim, S. M., Kim, S., Choi, H. M., Pyo, K., Kim, S. K., Lee, J. M., Lee, Y. W., Choi, J. W., Kim, H. R., et al. (2018) · Cancer Research · doi:10.1158/0008-5472.can-17-3146 · Cited by 43 · see citing works

Prenatal arsenic exposure alters the placental expression of multiple epigenetic regulators in a sex-dependent manner

Winterbottom, E. F., Moroishi, Y., Halchenko, Y., Armstrong, D. A., Beach, P., Nguyen, Q. P., Capobianco, A. J., Ayad, N. G., Marsit, C. J., Li, Z., et al. (2019) · Environmental Health · doi:10.1186/s12940-019-0455-9 · Cited by 42 · see citing works

Multi-omic analysis reveals significantly mutated genes and DDX3X as a sex-specific tumor suppressor in cutaneous melanoma

Alkallas, R., Lajoie, M., Moldoveanu, D., Hoang, K. V., Lefrançois, P., Lingrand, M., Ahanfeshar-Adams, M., Watters, K. A., Spatz, A., Zippin, J. H., et al. (2020) · Nature Cancer · doi:10.1038/s43018-020-0077-8 · Cited by 42 · see citing works

Effective inhibition of MYC-amplified group 3 medulloblastoma by FACT-targeted curaxin drug CBL0137

Wang, J., Sui, Y., Li, Q., Zhao, Y., Dong, X., Yang, J., Liang, Z., Han, Y., Tang, Y., & Ma, J. (2020) · Cell Death and Disease · doi:10.1038/s41419-020-03201-6 · Cited by 40 · see citing works

Single-Cell Quantitative Proteomic Analysis of Human Oocyte Maturation Revealed High Heterogeneity in In Vitro–Matured Oocytes

Guo, Y., Cai, L., Liu, X., Ma, L., Zhang, H., Wang, B., Qi, Y., Liu, J., Diao, F., Sha, J., et al. (2022) · Molecular & Cellular Proteomics · doi:10.1016/j.mcpro.2022.100267 · Cited by 42 · see citing works

Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference

Hop, P. J., Luijk, R., Daxinger, L., van Iterson, M., Dekkers, K. F., Jansen, R., Heijmans, B. T., Hoen, P. A. C. ’., van Meurs, J. B. J., Jansen, R., et al. (2020) · Genome biology · doi:10.1186/s13059-020-02114-z · Cited by 38 · see citing works

Annelid adult cell type diversity and their pluripotent cellular origins

Álvarez‐Campos, P., García-Castro, H., Emili, E., Pérez-Posada, A., del Olmo, I., Péron, S., Salamanca-Díaz, D. A., Mason, V., Metzger, B. M., Bely, A. E., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-47401-6 · Cited by 39 · see citing works

Interleukin-1β induces trained innate immunity in human hematopoietic progenitor cells in vitro

Gomez, D. F., Hobo, W. A., van Ens, D., Kessler, E. L., Novakovic, B., Schaap, N. P., Rijnen, W. H. C., Joosten, L. A. B., Netea, M. G., Riksen, N. P., et al. (2024) · Stem Cell Reports · doi:10.1016/j.stemcr.2024.09.004 · Cited by 42 · see citing works

Interactions Between Genetics, Lifestyle, and Environmental Factors for Healthcare

Lin, Y., Chen, J., & Shen, B. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-981-10-5717-5_8 · Cited by 39 · see citing works

Global epigenetic alterations of mesenchymal stem cells in obesity: the role of vitamin C reprogramming

Afarideh, M., Thaler, R., Khani, F., Tang, H. R., Jordan, K. L., Conley, S. M., Saadiq, I. M., Obeidat, Y., Pawar, A. S., Eirin, A., et al. (2020) · Epigenetics · doi:10.1080/15592294.2020.1819663 · Cited by 38 · see citing works

Integrative CAGE and DNA Methylation Profiling Identify Epigenetically Regulated Genes in NSCLC

Horie, M., Kaczkowski, B., Ohshima, M., Matsuzaki, H., Noguchi, S. F., Mikami, Y., Lizio, M., Itoh, M., Kawaji, H., Lassmann, T., et al. (2017) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-17-0191 · Cited by 36 · see citing works

Immune Cell Types and Secreted Factors Contributing to Inflammation-to-Cancer Transition and Immune Therapy Response

Chen, X., Chi, X., Hong, S., Xia, X., Cao, Y., McDermott, J., Mu, Y., & Han, J. J. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.01.080 · Cited by 36 · see citing works

Alterations of Chromatin Regulators in the Pathogenesis of Urinary Bladder Urothelial Carcinoma

Hoffmann, M. J., & Schulz, W. A. (2021) · Cancers · doi:10.3390/cancers13236040 · Cited by 37 · see citing works

A modular dCas9-based recruitment platform for combinatorial epigenome editing

Swain, T., Pflueger, C., Freytag, S., Poppe, D., Pflueger, J., Nguyen, T. V., Li, J. K., & Lister, R. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad1108 · Cited by 35 · see citing works

A computational method using the random walk with restart algorithm for identifying novel epigenetic factors

Li, J., Chen, L., Wang, S., Zhang, Y., Kong, X., Huang, T., & Cai, Y. (2017) · Molecular Genetics and Genomics · doi:10.1007/s00438-017-1374-5 · Cited by 35 · see citing works

CR2Cancer: a database for chromatin regulators in human cancer

Ru, B., Sun, J., Tong, Y., Wong, C. N., Chandra, A., Tang, A. T. S., Chow, L. K.-Y., Wun, W. L., Levitskaya, Z., & Zhang, J. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkx877 · Cited by 35 · see citing works

Plasmablasts derive from CD23– activated B cells after the extinction of IL-4/STAT6 signaling and IRF4 induction

Pignarre, A., Chatonnet, F., Caron, G., Haas, M., Desmots, F., & Fest, T. (2020) · Blood · doi:10.1182/blood.2020005083 · Cited by 35 · see citing works

Bioinformatic tools for DNA methylation and histone modification: A survey

Chenarani, N., Emamjomeh, A., Allahverdi, A., Mirmostafa, S., Afsharinia, M. H., & Zahiri, J. (2021) · Genomics · doi:10.1016/j.ygeno.2021.03.004 · Cited by 36 · see citing works

A neurodevelopmental epigenetic programme mediated by SMARCD3–DAB1–Reelin signalling is hijacked to promote medulloblastoma metastasis

Zou, H., Poore, B., Brown, E. E., Qian, J., Xie, B., Asimakidou, E., Razskazovskiy, V., Ayrapetian, D., Sharma, V., Xia, S., et al. (2023) · Nature Cell Biology · doi:10.1038/s41556-023-01093-0 · Cited by 35 · see citing works

Epigenetic and Immune-Cell Infiltration Changes in the Tumor Microenvironment in Hepatocellular Carcinoma

Wu, Z., Yang, D.-L., Wang, L., & Liu, J. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.793343 · Cited by 34 · see citing works

Specific hypomethylation programs underpin B cell activation in early multiple sclerosis

Ma, Q., Caillier, S. J., Muzic, S. I., Wilson, M. R., Henry, R. G., Cree, B., Hauser, S. L., Didonna, A., Oksenberg, J. R., Alexander, J., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2111920118 · Cited by 32 · see citing works

Decoding the Foodome: Molecular Networks Connecting Diet and Health

Menichetti, G., Barabási, A.-L., & Loscalzo, J. (2024) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-062322-030557 · Cited by 32 · see citing works

A modular CRISPR screen identifies individual and combination pathways contributing to HIV-1 latency

Hsieh, E., Janssens, D. H., Paddison, P. J., Browne, E. P., Henikoff, S., OhAinle, M., & Emerman, M. (2023) · PLoS Pathogens · doi:10.1371/journal.ppat.1011101 · Cited by 31 · see citing works

Epigenome alterations in aortic valve stenosis and its related left ventricular hypertrophy

Gošev, I., Zeljko, M., Đurić, Ž., Nikolić, I., Gošev, M., Ivčević, S., Bešić, D., Legčević, Z., & Paić, F. (2017) · Clinical Epigenetics · doi:10.1186/s13148-017-0406-7 · Cited by 31 · see citing works

Transcription factor C/EBPβ induces genome-wide H3K27ac and upregulates gene expression during decidualization of human endometrial stromal cells

Tamura, I., Maekawa, R., Jozaki, K., Ohkawa, Y., Takagi, H., Doi‐Tanaka, Y., Shirafuta, Y., Mihara, Y., Taketani, T., Sato, S., et al. (2020) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2020.111085 · Cited by 31 · see citing works

Epigenetic Target Fishing with Accurate Machine Learning Models

Sánchez‐Cruz, N., & Medina‐Franco, J. L. (2021) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.1c00020 · Cited by 30 · see citing works

The role of CPT1A as a biomarker of breast cancer progression: a bioinformatic approach

Das, M., Giannoudis, A., & Sharma, V. S. (2022) · Scientific Reports · doi:10.1038/s41598-022-20585-x · Cited by 30 · see citing works

High‐resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD

Schwartz, U., Prada, M. L., Pohl, S. T., Richter, M., Tamas, R., Schuler, M. J., Keller, C., Mijošek, V., Muley, T., Schneider, M. A., et al. (2023) · The EMBO Journal · doi:10.15252/embj.2022111272 · Cited by 29 · see citing works

A comprehensive atlas of epigenetic regulators reveals tissue-specific epigenetic regulation patterns

Wang, J., Shi, A., & Lyu, J. (2022) · Epigenetics · doi:10.1080/15592294.2022.2139067 · Cited by 28 · see citing works

Epigenetic and Tumor Microenvironment for Prognosis of Patients with Gastric Cancer

Wu, Z., Wang, W., Zhang, K., Fan, M., & Lin, R. (2023) · Biomolecules · doi:10.3390/biom13050736 · Cited by 28 · see citing works

CTCF and Its Multi-Partner Network for Chromatin Regulation

del Moral-Morales, A., Salgado-Albarrán, M., Sánchez-Pérez, Y., Wenke, N., Baumbach, J., & Soto-Reyes, E. (2023) · Cells · doi:10.3390/cells12101357 · Cited by 27 · see citing works

Preservation of methylated CpG dinucleotides in human CpG islands

Panchin, A. Y., Makeev, V. J., & Medvedeva, Y. A. (2016) · Biology Direct · doi:10.1186/s13062-016-0113-x · Cited by 27 · see citing works

A pan-cancer analysis of driver gene mutations, DNA methylation and gene expressions reveals that chromatin remodeling is a major mechanism inducing global changes in cancer epigenomes

Youn, A., Kim, K. I., Rabadán, R., Tycko, B., Shen, Y., & Wang, S. (2018) · BMC Medical Genomics · doi:10.1186/s12920-018-0425-z · Cited by 28 · see citing works

EPIKOL, a chromatin-focused CRISPR/Cas9-based screening platform, to identify cancer-specific epigenetic vulnerabilities

Yedier-Bayram, O., Gokbayrak, B., Kayabölen, A., Aksu, A. C., Cavga, A. D., Cingöz, A., Kala, E. Y., Karabiyik, G., Günsay, R., Esin, B., et al. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-05146-4 · Cited by 25 · see citing works

Pan-cancer landscape of epigenetic factor expression predicts tumor outcome

Cheng, M. W., Mitra, M., & Coller, H. A. (2023) · Communications Biology · doi:10.1038/s42003-023-05459-w · Cited by 26 · see citing works

Human chromatin remodeler cofactor, RNA interactor, eraser and writer sperm RNAs responding to obesity

Swanson, G., Estill, M. S., Diamond, M. P., Legro, R. S., Coutifaris, C., Barnhart, K. T., Huang, H., Hansen, K. R., Trussell, J. C., Coward, R. M., et al. (2019) · Epigenetics · doi:10.1080/15592294.2019.1644880 · Cited by 26 · see citing works

Can cloud-based tools accelerate Alzheimer’s disease drug discovery?

Cacabelos, R., Teijido, Ó., & Carril, J. C. (2016) · Expert Opinion on Drug Discovery · doi:10.1517/17460441.2016.1141892 · Cited by 26 · see citing works

Expression profiling of cell-intrinsic regulators in the process of differentiation of human iPSCs into retinal lineages

Chuang, J.-H., Yarmishyn, A. A., Hwang, D., Hsu, C., Wang, M., Yang, Y.-P., Chien, K., Chiou, S., Peng, C., & Chen, S. (2018) · Stem Cell Research & Therapy · doi:10.1186/s13287-018-0848-7 · Cited by 25 · see citing works

Amygdala 5-HTT Gene Network Moderates the Effects of Postnatal Adversity on Attention Problems: Anatomo-Functional Correlation and Epigenetic Changes

de Lima, R. M. S., Barth, B., Arcego, D. M., Filho, E. J. D. M., Clappison, A. S., Patel, S. H., Wang, Z., Pokhvisneva, I., Sassi, R. B., Hall, G. B., et al. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00198 · Cited by 24 · see citing works

The Chromatin Regulator ZMYM2 Restricts Human Pluripotent Stem Cell Growth and Is Essential for Teratoma Formation

Lezmi, E., Weissbein, U., Golan‐Lev, T., Nissim‐Rafinia, M., Meshorer, E., & Benvenisty, N. (2020) · Stem Cell Reports · doi:10.1016/j.stemcr.2020.05.014 · Cited by 24 · see citing works

Identifying regulators of parental imprinting by CRISPR/Cas9 screening in haploid human embryonic stem cells

Bar, S., Vershkov, D., Keshet, G., Lezmi, E., Meller, N., Yilmaz, A., Yanuka, O., Nissim‐Rafinia, M., Meshorer, E., Eldar‐Geva, T., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-26949-7 · Cited by 24 · see citing works

DNA hypermethylation driven by DNMT1 and DNMT3A favors tumor immune escape contributing to the aggressiveness of adrenocortical carcinoma

Kerdivel, G., Amrouche, F., Calméjane, M.-A., Carallis, F., Hamroune, J., Hantel, C., Bertherat, J. Y., Assié, G., & Boeva, V. (2023) · Clinical Epigenetics · doi:10.1186/s13148-023-01534-5 · Cited by 23 · see citing works

Cross Talk Between Bacteria and the Host Epigenetic Machinery

Bierne, H. (2017) · Epigenetics and human health · doi:10.1007/978-3-319-55021-3_6 · Cited by 23 · see citing works

Gene Signature of Proliferating Human Pancreatic α Cells

Gutiérrez, G. D., Xin, Y., Okamoto, H., Kim, J., Lee, A., Ni, M., Adler, C., Yancopoulos, G. D., Murphy, A. J., & Gromada, J. (2018) · Endocrinology · doi:10.1210/en.2018-00469 · Cited by 22 · see citing works

Functional Genomics

kaushik, S., Kaushik, S., & Sharma, D. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-809633-8.20222-7 · Cited by 23 · see citing works

Distinct and diverse chromatin proteomes of ageing mouse organs reveal protein signatures that correlate with physiological functions

Oliviero, G., Kovalchuk, S. I., Rogowska-Wrzesińska, A., Schwämmle, V., & Jensen, O. N. (2022) · eLife · doi:10.7554/elife.73524 · Cited by 25 · see citing works

Integrated multiomic analysis and high‐throughput screening reveal potential gene targets and synergetic drug combinations for osteosarcoma therapy

Zhang, W., Qi, L., Liu, Z., He, S., Wang, C., Wu, Y., Han, L., Liu, Z., Fu, Z., Tu, C., et al. (2023) · MedComm · doi:10.1002/mco2.317 · Cited by 20 · see citing works

P53 at the start of the 21st century: lessons from elephants

Haupt, S., & Haupt, Y. (2017) · F1000Research · doi:10.12688/f1000research.12682.1 · Cited by 20 · see citing works

KMT1 family methyltransferases regulate heterochromatin–nuclear periphery tethering via histone and non‐histone protein methylation

Rao, R. A., Ketkar, A. A., Kedia, N., Krishnamoorthy, V. K., Lakshmanan, V., Kumar, P., Mohanty, A., Kumar, S. D., Raja, S. O., Gulyani, A., et al. (2019) · EMBO Reports · doi:10.15252/embr.201643260 · Cited by 21 · see citing works

Original article EpiFactors: a comprehensive database of human epigenetic factors and complexes

Medvedeva, Y. A., Lennartsson, A., Ehsani, R., Kulakovskiy, I. V., Vorontsov, I. E., Panah, P., Khimulya, G., Kasukawa, T., & The Fantom Consortium (2016)

EpiFactors 2022: expansion and enhancement of a curated database of human epigenetic factors and complexes

Marakulina, D., Vorontsov, I. E., Kulakovskiy, I. V., Lennartsson, A., Drabløs, F., & Medvedeva, Y. A. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkac989 · Cited by 78 · see citing works

EpiNet: A multilayer integrative atlas of the human epigenetic regulatory network reveals principles of complex assembly, domain modularity, and lncRNA scaffoldingPreprint

BOUGARNE, A. (2026) · Research Square · doi:10.21203/rs.3.rs-10362416/v1

EpiRegNet: Constructing epigenetic regulatory network from high throughput gene expression data for humans

Wang, L. Y., Wang, P., Li, M. J., Qin, J., Wang, X., Zhang, M. Q., & Wang, J. (2011) · Epigenetics · doi:10.4161/epi.6.12.18176 · Cited by 21 · see citing works

EPITRANS: A Database that Integrates Epigenome and Transcriptome Data

Cho, S. Y., Chai, J. C., Park, S. J., Seo, H., Sohn, C.-B., & Lee, Y. S. (2013) · Molecules and Cells · doi:10.1007/s10059-013-0249-9 · Cited by 7 · see citing works