Cited by 601

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination

Staub, O., Gautschi, I., Ishikawa, T., Breitschopf, K., Ciechanover, A., Schild, L., Rotin, D.·1997·The EMBO Journal

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1093/emboj/16.21.6325

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 59

  1. Andersson S, Davis DL, Dahlbaeck H, Joernvall H and Russell DW (1989) Cloning, structure, and expression of the mitochondrial cytochrome P‐450 sterol 26‐hydroxylase, a bile acid biosynthetic enzyme. J Biol Chem, 264, 8222–8229. · DOI
  2. Botero‐Velez M, Curtis JJ and Warnock DG (1994) Brief report: Liddles's syndrome revisited. New Engl J Med, 330, 178–181. · DOI
  3. Brodsky JL and McCracken AA (1997) ER‐associated and proteasome‐mediated protein degradation: how two topologically restricted events came together. Trends Cell Biol, 7, 151–156. · DOI
  4. Canessa CM, Horisberger J‐D and Rossier BC (1993) Epithelial sodium channel related to proteins involved in neurodegeneration. Nature, 361, 467–470. · DOI
  5. Canessa CM, Schild L, Buell G, Thorens B, Gautschi I, Horisberger J‐D and Rossier BC (1994a) Amiloride‐sensitive epithelial Na+ channel is made of three homologous subunits. Nature, 367, 463–467. · DOI
  6. Canessa CM, Mérillat A‐M and RossierBC (1994b) Membrane topology of the epithelial sodium channel in intact cells. Am J Physiol, 267, C1682–C1690. · DOI
  7. Cenciarelli C, Hou D, Hsu K, Rellahan BL, Wiest DL, Smith HT, Fried VA and Weissman AM (1992) Activation‐induced ubiquitination of the T cell antigen receptor. Science, 257, 795–797. · DOI
  8. Ciechanover A (1994) The ubiquitin‐proteasome proteolytic pathway. Cell, 79, 13–21. · DOI
  9. Deshaies RJ (1995) Make it or break it: The role of ubiquitin‐dependent proteolysis in cellular regulation. Trends Cell Biol, 5, 428–434. · DOI
  10. Duc D, Farman N, Canessa CM, Bonvalet J‐P and Rossier BC (1994) Cell‐specific expression of epithelial sodium channel α, β and γ subunits in aldosterone‐responsive epithelia from the rat: localization by in situ hybridization and immunocytochemistry. J Cell Biol, 127, 1907–1921. · DOI
  11. Egner R and Kuchler K (1996) The yeast multidrug transporter Pdr5 of the plasma membrane is ubiquitinated prior to endocytosis and degradation in the vacuole. FEBS Lett, 378, 177–181. · DOI
  12. Fenteany G, Standaert RF, Lane WS, Chois S, Corey EJ and Schreiber SL (1995) Inhibition of proteasome activities and subunit‐specific amino‐terminal threonine modification by lactacystin. Science, 268, 726–731. · DOI · Paper page
  13. Firsov D, Schild L, Gautschi I, Mérillat A‐M, Schneeberger E and Rossier BC (1996) Cell surface expression of the epithelial Na+ channel and a mutant causing Liddle syndrome: a quantitative approach. Proc Natl Acad Sci USA, 93, 15370–15375. · DOI
  14. Galan JM, Moreau V, André B, Volland C and Haguenauer‐Tsapis R (1996) Ubiquitination mediated by the Npi1p/Rsp5p ubiquitin‐protein ligase is required for endocytosis of the yeast uracil permease. J Biol Chem, 271, 10946–10952. · DOI
  15. Galcheva‐Garbova Z, Theroux SJ and Davis RJ (1995) The epidermal growth factor receptor is covalently linked to ubiquitin. Oncogene, 11, 2649–2655.
  16. Garty H and Palmer LG (1997) Epithelial sodium channels: function, structure, and regulation. Physiol Rev, 77, 359–396. · DOI
  17. Geering K, Beggah A, Good P, Girardet S, Roy S, Schaer D and Jaunin P (1996) Oligomerization and maturation of Na,K‐ATPase: Functional interaction of the cytoplasmic NH2 terminus of the beta subunit with the alpha subunit. J Cell Biol, 133, 1193–1204. · DOI
  18. Hansson JH et al. (1995a) Hypertension caused by a truncated epithelial sodium channel gamma subunit: Genetic heterogeneity of Liddle syndrome. Nature Genet, 11, 76–82. · DOI
  19. Hansson JH, Schild L, Lu Y, Wilson TA, Gautschi I, Shimkets RA, Nelson‐Williams C, Rossier BC and Lifton RP (1995b) A de novo missense mutation of the β subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline‐rich segment critical for regulation of channel activity. Proc Natl Acad Sci USA, 25, 11495–11499. · DOI
  20. Hein C, Springael JY, Volland C, Haguenauer‐Tsapis R and André B (1995) NPI1, an essential yeast gene involved in induced degradation of Gap1 and Fur4 permeases, encodes the Rsp5 ubiquitin‐protein ligase. Mol Microbiol, 18, 77–87. · DOI
  21. Hicke L and Riezman H (1996) Ubiquitination of a yeast plasma membrane receptor signals its ligand‐stimulated endocytosis. Cell, 84, 277–287. · DOI · Paper page
  22. Hilt W and Wolf DH (1996) Proteasomes: destruction as a programme. Trends Biochem Sci, 21, 96–102. · DOI
  23. Hirt RP, Poulain‐Godefroy O, Billotte J, Kraehenbuhel J‐P and Fasel N (1992) Highly inducible synthesis of heterologous proteins in epithelial cells carrying a glucocorticoid‐responsive vector. Gene, 111, 199–206. · DOI
  24. Hochstrasser M (1996) Protein degradation or regulation: Ub the judge. Cell, 84, 813–815. · DOI
  25. Hummler E, Barker P, Gatzy J, Beermann F, Verdumo C, Schmidt A, Boucher RC and Rossier BC (1996) Early death due to defective neonatal lung liquid clearance in αENaC‐deficient mice. Nature Genet, 12, 325–328. · DOI
  26. Jensen TJ, Loo MA, Pind S, Williams DB, Goldberg AL and Riordan JR (1995) Multiple proteolytic systems including the proteasome, contribute to CFTR processing. Cell, 83, 129–135. · DOI
  27. Jentsch S and Schlenker S (1995) Selective protein degradation: a journey's end within the proteasome. Cell, 82, 881–884. · DOI
  28. Kölling R and Hollenberg CP (1994) The ABC‐transporter Ste6 accumulates in the plasma membrane in a ubiquitinated form in endocytosis mutants. EMBO J, 13, 3261–3271. · DOI
  29. Liddle GW, Bledsoe T and Coppage WS,Jr (1963) A familial renal disorder simulating primary aldosteronism but with negligible aldosterone secretion. Trans Assoc Am Physicians, 76, 199–213.
  30. Lingueglia E, Voilley N, Waldmann R, Lazdunski M and Barbry P (1993) Expression cloning of an epithelial amiloride‐sensitive Na+ channel. A new channel type with homologies to Caenorhabditis elegans degenerins. FEBS Lett, 318, 95–99. · DOI
  31. Lingueglia E, Renard S, Waldmann R, Voilley N, Champigny G, Plass H, Lazdunski M and Barbry P (1994) Different homologous subunits of the amiloride‐sensitive Na+ channel are differently regulated by aldosterone. J Biol Chem, 269, 13736–13739. · DOI
  32. McDonald FJ, Snyder PM, McCray PB,Jr and Welsh MJ (1994) Cloning, expression, and distribution of a human amiloride‐sensitive Na+ channel. Am J Physiol, 266, L728–L734.
  33. McDonald FJ, Price MP, Snyder PM and Welsh MJ (1995) Cloning and expression of the β‐ and γ‐subunits of the human epithelial sodium channel. Am J Physiol, 268, C1157–C1163. · DOI
  34. Miyazawa K, Toyama K, Gotoh A, Hendrie PC, Mantel C and Broxmeyer HE (1994) Ligand‐dependent polyubiquitination of c‐kit gene product: a possible mechanism of receptor down modulation in M07e cells. Blood, 83, 137–145. · DOI
  35. Mori S, Heldin C‐H and Claesson‐Welsh L (1992) Ligand‐induced polyubiquitination of the platelet‐derived growth factor β‐receptor. J Biol Chem, 267, 6429–6434. · DOI
  36. Nelson RM and Long GL (1989) A general method of site‐specific mutagenesis using a modification of the Thermus aquatiqus polymerase chain reaction. Anal Biochem, 180, 147–151. · DOI
  37. O'Brodovich H (1995) The role of active Na+ transport by lung epithelium in the clearance of airspace fluid. New Horizons, 3, 240–247.
  38. Palombella V, Rando O, Goldberg AL and Maniatis T (1994) Ubiquitin and the proteasome are required for processing the NF‐κB1 precursor and the activation of NF‐κB. Cell, 78, 773–785. · DOI
  39. Paolini R and Kinet J‐P (1993) Cell surface control of the multiubiquitination and deubiquitination of high‐affinity immunoglobulin E receptors. EMBO J, 12, 779–786. · DOI
  40. Puoti A, May A, Canessa CM, Horisberger J‐D, Schild L and Rossier BC (1995) The highly selective low‐conductance epithelial Na+ channel of Xenopus laevis A6 kidney cells. Am J Physiol, 38, C188–C197. · DOI
  41. Renard S, Lingueglia E, Voilley N, Lazdunski M and Barbry P (1994) Biochemical analysis of the membrane topology of the amiloride‐sensitive Na+ channel. J Biol Chem, 269, 12981–12986. · DOI
  42. Rossier BC and Palmer LG (1992) Mechanisms of aldosterone action on sodium and potassium transport. In Seldin,D.W. and Giebisch,G. (eds), The Kidney: Physiology and Pathophysiology. Raven Press, New York, USA, pp. 1373–1409.
  43. Rotin D, Bar‐Sagi D, O'Brodovich H, Merilainen J, Lehto PV, Canessa CM, Rossier BC and Downey GP (1994) A SH3 binding region in the epithelial Na+ channel (ENaC) mediates its localization at the apical membrane. EMBO J, 13, 4440–4450. · DOI
  44. Saumon G and Basset G (1993) Electrolyte and fluid transport across the mature alveolar epithelium. J Appl Physiol, 74, 1–15. · DOI
  45. Scheffner M, Huibregtse JM, Vierstra R and Howley PM (1993) The HPV‐16 E6 and E6‐AP complex functions as a ubiquitin‐protein ligase in the ubiquitination of p53. Cell, 75, 495–505. · DOI
  46. Schild L, Canessa CM, Shimkets RA, Warnock DG, Lifton RP and Rossier BC (1995) A mutation in the epithelial sodium channel causing Liddle's disease increases channel activity in the Xenopus laevis oocyte expression system. Proc Natl Acad Sci USA, 92, 5699–5703. · DOI · Paper page
  47. Schild L, Lu Y, Gautschi I, Schneeberger E, Lifton RP and Rossier BC (1996) Identification of a PY motif in the epithelial Na+ channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome. EMBO J, 15, 2381–2387. · DOI
  48. Schild L, Schneeberger E, Gautschi I and Firsov D (1997) Identification of amino acid residues in the alpha, beta and gamma subunits of the epithelial sodium channel (ENaC) involved in amiloride block and ion permeation. J Gen Physiol, 109, 15–26. · DOI
  49. Shimkets RA et al. (1994) Liddles's syndrome: heritable human hypertension caused by mutations in the β subunit of the epithelial sodium channel. Cell, 79, 407–414. · DOI
  50. Snyder PM, McDonald FJ, Stokes JB and Welsh MJ (1994) Membrane topology of the amiloride‐sensitive epithelial sodium channel. J Biol Chem, 269, 24379–24383. · DOI
  51. Snyder PM, Price MP, McDonald FJ, Adams CM, Volk KA, Zeiher BG, Stokes JB and Welsh MJ (1995) Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel. Cell, 83, 969–978. · DOI · Paper page
  52. Staub O, Dho S, Henry PC, Correa J, Ishikawa T, McGlade J and Rotin D (1996) WW domains of Nedd4 bind to the proline‐rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome. EMBO J, 15, 2371–2380. · DOI
  53. Strautnieks SS, Thompson RJ, Gardiner RM and Chung E (1996) A novel splice‐site mutation in the gamma subunit of the epithelial sodium channel gene in three pseudohypoaldosteronism type 1 families. Nature Genet, 13, 248–250. · DOI
  54. Strous GJ, Van Kerkhof P, Govers R, Ciechanover A and Schwartz AL (1996) The ubiquitin conjugation system is required for ligand‐induced endocytosis and degradation of the growth hormone receptor. EMBO J, 15, 3806–3812. · DOI
  55. Stutts MJ, Canessa CM, Olsen JC, Hamrick M, Cohn JA, Rossier BC and Boucher RC (1995) CFTR as a cAMP‐dependent regulator of sodium channels. Science, 269, 847–850. · DOI
  56. Tamura H, Schild L, Enomoto N, Matsui N, Marumo F, Rossier BC and Sasaki S (1996) Liddle disease caused by a missense mutation of beta subunit of the epithelial sodium channel gene. J Clin Invest, 97, 1780–1784. · DOI
  57. Treier M, Staszewski LM and Bohmann D (1994) Ubiquitin‐dependent c‐Jun degradation in vivo is mediated by the δ domain. Cell, 78, 787–798. · DOI
  58. Voilley N, Lingueglia E, Champigny G, Mattéi M‐G, Waldmann R, Lazdunski M and Barbry P (1994) The lung amiloride‐sensitive Na+ channel: Biophysical properties, pharmacology, ontogenesis, and molecular cloning. Proc Natl Acad Sci USA, 91, 247–251. · DOI
  59. Ward CL, Omura S and Kopito RR (1995) Degradation of CFTR by the ubiquitin‐proteasome pathway. Cell, 83, 121–127. · DOI

Cited by

Sorted by citations

Metadata

Authors
Staub, O., Gautschi, I., Ishikawa, T., Breitschopf, K., Ciechanover, A., Schild, L., & Rotin, D.
Venue
The EMBO Journal
Published
1997-11-01
Volume
16
Issue
21
Pages
6325-6336
ISSN
  • 0261-4189
  • 1460-2075
Cited by
601
References
1
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review