Different telomere damage signaling pathways in human and mouse cells

Smogorzewska, Agata, de Lange, Titia·2002·The EMBO Journal

Cited by (480)

Items 301–400 of 480

  1. Telomere erosion in human pluripotent stem cells leads to ATR-mediated mitotic catastrophe
    Alexandre Teixeira Vessoni, Tianpeng Zhang, Annabel Quinet, Ho‐Chang Jeong, Michael Munroe, Matthew D. Wood, Enzo Tedone, Alessandro Vindigni, Jerry W. Shay, Roger A. Greenberg et al. · 2021 · The Journal of Cell Biology
  2. Telomere shortening is associated with malformation in p53-deficient mice after irradiation during specific stages of development
    Sofie Bekaert, Hanane Derradji, Tim De Meyer, Arlette Michaux, Jasmine Buset, Mieke Neefs, Max Mergeay, Paul Jacquet, Patrick Van Oostveldt, Sarah Baatout · 2005 · DNA repair
  3. Telomerase as a clinical target: Current strategies and potential applications
    Helen B. Fleisig, Judy M.Y. Wong · 2006 · Experimental Gerontology
  4. Anticancer Therapy Targeting Telomeres and Telomerase
    Eric Kenneth Parkinson, Fay Minty · 2007 · BioDrugs
  5. Retraction
    Lucy Cassar, Craig Nicholls, Alexander Ruvantha Pinto, He Li, Junping Liu · 2009 · The FASEB Journal · Retracted
  6. Hematopoietic stem cells are acutely sensitive to Acd shelterin gene inactivation
    Jones, Morgan, Osawa, Gail, Regal, Joshua A., Weinberg, Daniel N., Taggart, James, Kocak, Hande, Friedman, Ann, Ferguson, David O., Keegan, Catherine E., Maillard, Ivan · 2014 · Journal of Clinical Investigation
  7. The role of replicative senescence in cancer and human ageing: utility (or otherwise) of murine models
    S. Kaye Smith, David Kipling · 2004 · Cytogenetic and Genome Research
  8. p53 and telomerase control rat myocardial tissue response to hypoxia and ageing
    Amelia Cataldi, Susi Zara, Monica Rapino, Maria Zingariello, Viviana di Giacomo, Adriano Torres Antonucci · 2009 · European Journal of Histochemistry
  9. Effectors of mammalian telomere dysfunction: a comparative transcriptome analysis using mouse models
    Sonia Franco, Andrés Canela, Peter Klatt, Marı́a A. Blasco · 2005 · Carcinogenesis
  10. Transcriptional and proteomic characterization of telomere-induced senescence in a human alveolar epithelial cell line
    Sullivan, Daniel I., Jiang, Mao, Hinchie, Angela M., Roth, Mark G., Bahudhanapati, Harinath, Nouraie, Mehdi, Liu, Jie, McDyer, John F., Mallampalli, Rama K., Zhang, Yingze et al. · 2021 · Frontiers in Medicine
  11. TRF1 and TRF2: pioneering targets in telomere-based cancer therapy
    Anoop Kallingal, Radosław Krzemieniecki, Natalia Maciejewska, Wioletta Brankiewicz, Maciej Bagiński · 2024 · Journal of Cancer Research and Clinical Oncology
  12. Homologous recombination-mediated irreversible genome damage underlies telomere-induced senescence
    Sabrina Ghadaouia, Marc‐Alexandre Olivier, Aurélie Martinez, Tibila Kientega, Qin Jian, Patrick Lambert-Lanteigne, Guillaume B. Cardin, Chantal Autexier, Nicolas Malaquin, Françis Rodier · 2021 · Nucleic Acids Research
  13. The Telomeric Protein TRF2 Is Critical for the Protection of A549 Cells from Both Telomere Erosion and DNA Double-Strand Breaks Driven by Salvicine
    Yongwei Zhang, Zhixiang Zhang, Ze‐Hong Miao, Jian Ding · 2007 · Molecular Pharmacology
  14. mTert induction in p21-positive cells counteracts capillary rarefaction and pulmonary emphysema
    Larissa Lipskaia, Marielle Breau, Christelle Cayrou, Dmitri Churikov, Laura Braud, Juliette Jacquet, Emmanuelle Born, Charles Fouillade, Sandra Curras-Alonso, Serge Bauwens et al. · 2024 · EMBO Reports
  15. Higher DNA repair activity is related with longer replicative life span in mammalian embryonic fibroblast cells
    Seong‐Hoon Park, Hongjun Kang, Hyun-Seok Kim, Min-Ju Kim, Jee‐In Heo, Jeong‐Hyeon Kim, Yoonjung Kho, Sung Chan Kim, Jaebong Kim, Jae‐Bong Park et al. · 2011 · Biogerontology
  16. Clinical Implications of Cellular Senescence on Wound Healing
    S.G. Resnik, Andjela N. Egger, Beatriz Abdo Abujamra, Ivan Jozic · 2020 · Current Dermatology Reports
  17. Nuclear imaging in three dimensions: A unique tool in cancer research
    Thomas C. Klonisch, Landon Wark, Sabine Hombach‐Klonisch, Sabine Mai · 2010 · Annals of Anatomy - Anatomischer Anzeiger
  18. Polypeptide Components of Telomere Nucleoprotein Complex
    Alexander N. Kuimov · 2004 · Biochemistry (Moscow)
  19. Attenuation of ATM signaling by ROS delays replicative senescence at physiological oxygen
    Alexander Stuart, Kaori Takai, Railia R Gabbasova, Henry Sanford, Ekaterina V. Vinogradova, Titia de Lange · 2025 · Molecular Cell
  20. Role for the shelterin protein TRF2 in human herpesvirus 6A/B chromosomal integration
    Shella Gilbert-Girard, Annie Gravel, Vanessa Collin, Darren J. Wight, Benedikt B. Kaufer, Eros Lazzerini Denchi, Louis Flamand · 2020 · PLoS Pathogens
  21. Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeres
    Radka Storchova, Matous Palek, Natálie Palková, Pavel Veverka, Tomáš Brom, Ctirad Hofr, Libor Macůrek · 2023 · Nucleic Acids Research
  22. The role of telomere shortening in carcinogenesis: A hybrid stochastic-deterministic approach
    Ignacio A. Rodriguez-Brenes, Natalia L. Komarova, Dominik Wodarz · 2018 · Journal of Theoretical Biology
  23. Telomere dysfunction in human keratinocytes elicits senescence and a novel transcription profile
    Fay Minty, Johanna K. Thurlow, P HARRISON, Eric Kenneth Parkinson · 2008 · Experimental Cell Research
  24. Small molecule, oligonucleotide-based telomerase template inhibition in combination with cytolytic therapy in an in vitro androgen-independent prostate cancer model
    Benjamin K. Canales, Yingming Li, Melissa G. Thompson, Joseph M. Gleason, Zhi Chen, Bahaa S. Malaeb, David R. Corey, Brittney‐Shea Herbert, Jerry W. Shay, Kenneth S. Koeneman · 2006 · Urologic Oncology Seminars and Original Investigations
  25. CRISPR screen identifies CEBPB as contributor to dyskeratosis congenita fibroblast senescence via augmented inflammatory gene response
    Erik R. Westin, Alireza Khodadadi‐Jamayran, Linh K. Pham, Moon Ley Tung, Frederick D. Goldman · 2023 · G3 Genes Genomes Genetics
  26. Senescent mesenchymal stem/stromal cells in pre-metastatic bone marrow of untreated advanced breast cancer patients
    Francisco Raúl Borzone, María Belén Giorello, Leandro Marcelo Martinez, María Cecilia Sanmartin, Leonardo Julio Feldman, Federico Dimase, Emilio Batagelj, Gustavo Yannarelli, Norma Alejandra Chasseing · 2023 · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
  27. Mutant telomerase RNAs induce DNA damage and apoptosis via the TRF2‐ATM pathway in telomerase‐overexpressing primary fibroblasts
    Dashayini Mahalingam, Ling Lee Tay, Wei Han Tan, Juin Hsien Chai, Yuqin Wang · 2011 · FEBS Journal
  28. Mechanism of interaction of small transcription inhibitors with DNA in the context of chromatin and telomere
    Saptaparni Ghosh, Parijat Majumder, Suman Kalyan Pradhan, Dipak Dasgupta · 2010 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
  29. Stem cell expansion during carcinogenesis in stem cell-depleted conditional telomeric repeat factor 2 null mutant mice
    Bojana Bojović, H-Y Ho, Jingting Wu, David L. Crowe · 2012 · Oncogene
  30. How Cardiomyocytes Make the Heart Old
    Zoltán Lajos Papp, Dániel Czuriga, Laszlo Balogh, Agnes Balogh, Attila Borbély · 2012 · Current Pharmaceutical Biotechnology
  31. Telomere DNA damage signaling regulates cancer stem cell evolution, epithelial mesenchymal transition, and metastasis
    Angelica M. Lagunas, Jianchun Wu, David L. Crowe · 2017 · Oncotarget
  32. No attenuation of the ATM-dependent DNA damage response in murine telomerase-deficient cells
    Natalie Erdmann, Lea A. Harrington · 2008 · DNA repair
  33. Characterization of the telomere complex, TERF1 and TERF2 genes in muntjac species with fusion karyotypes
    Nils Hartmann, Harry Scherthan · 2005 · Experimental Cell Research
  34. Intestinal crypt properties fit a model that incorporates replicative ageing and deep and proximate stem cells
    Pavel N. Lobachevsky, Ian R. Radford · 2006 · Cell Proliferation
  35. Transcription factor Sp1 prevents TRF2ΔBΔM-induced premature senescence in human diploid fibroblasts
    Hyun‐Ju An, Hyeon Ju Lee, Su Hwa Jang, Yu‐Jin Jung, Sun Shim Choi, Sang Chul Park, Jeong A. Han · 2016 · Molecular and Cellular Biochemistry
  36. Telomere Crisis Shapes Cancer Evolution
    Joe Nassour, Jan Karlseder · 2025 · Cold Spring Harbor Perspectives in Biology
  37. Patient-Induced Pluripotent Stem Cell–Derived Hepatostellate Organoids Establish a Basis for Liver Pathologies in Telomeropathies
    Young‐Jun Choi, Melissa S. Kim, Joshua H. Rhoades, Nicolette M. Johnson, Corbett T. Berry, Sarah Root, Qijun Chen, Yuhua Tian, Rafael Jesus Fernandez, Zvi Cramer et al. · 2023 · Cellular and Molecular Gastroenterology and Hepatology
  38. Role of telomere length in subtelomeric gene expression and its possible relation to cellular senescence
    Marta Elena Hernández-Caballero, Norma Estela Herrera-González, Fabio Salamanca-Gómez, Diego Julio Arenas-Aranda · 2009 · BMB Reports
  39. DNA damage response, checkpoint activation and dysfunctional telomeres: face to face between mammalian cells and Drosophila.
    Francesca Cipressa, Giovanni Cenci · 2013 · PubMed
  40. H2B Type 1-K Accumulates in Senescent Fibroblasts with Persistent DNA Damage along with Methylated and Phosphorylated Forms of HMGA1
    Kévin Contrepois, Carl Mann, François Fenaille · 2021 · Proteomes
  41. Modification of the telomerase gene with human regulatory sequences resets mouse telomeres to human length
    Fan Zhang, De Cheng, Kenneth I. Porter, Emily A. Heck, Shuwen Wang, Hui Zhang, Christopher J. Davis, Gavin P. Robertson, Jiyue Zhu · 2025 · Nature Communications
  42. Inhibition of TRF2 Leads to Ferroptosis, Autophagic Death, and Apoptosis by Causing Telomere Dysfunction
    Qiuhui Yang, Ziyang Nie, Yukun Zhu, Mingying Hao, Siqi Liu, Xuelu Ding, Feng Wang, Fei Wang, Xin Geng · 2023 · Oxidative Medicine and Cellular Longevity
  43. Pathology of Aging Skin
    Qunshan Jia, J. Frank Nash · 2015 · Springer eBooks
  44. The secreted protein S100A7 (psoriasin) is induced by telomere dysfunction in human keratinocytes independently of a DNA damage response and cell cycle regulators
    Alice de Castro, Fay Minty, Eva Hattinger, Ronald Wolf, Eric Kenneth Parkinson · 2014 · Longevity & Healthspan
  45. Vitamin D Supplementation Reverses DNA Damage and Telomeres Shortening Caused by Ovariectomy in Hippocampus of Wistar Rats
    Cassiana Siebert, Tiago Marcon dos Santos, Carolina Gessinger Bertó, Mariana Migliorini Parisi, Ritiéle Pinto Coelho, Vanusa Manfredini, Florencia María Barbé‐Tuana, Ângela Terezinha de Souza Wyse · 2018 · Neurotoxicity Research
  46. Human stem cells, chromatin, and tissue engineering: Boosting relevancy in developmental toxicity testing
    Elizabeth Cho, Wan‐Ju Li · 2007 · Birth Defects Research Part C Embryo Today Reviews
  47. Targeting mitochondrial dysfunction to salvage cellular senescence for managing neurodegeneration
    Komal Sharma, Joyobrata Sarkar, Anchal Trisal, Rishika Ghosh, Anubhuti Dixit, Abhishek Kumar Singh · 2023 · Advances in protein chemistry and structural biology
  48. Epigenetic reprogramming for ocular aging and disease: Mechanisms, biomarkers, and the road to the clinic
    Junwon Lee, Minseok Han, Kaixiang Wang, L.Rainer Butler, David A. Sinclair · 2026 · Progress in Retinal and Eye Research
  49. Stretching, scrambling, piercing and entangling: Challenges for telomeres in mitotic and meiotic chromosome segregation
    Haitong Hou, Julia Promisel Cooper · 2018 · Differentiation
  50. Telomeres in Aging: Birds
    Susan E. Swanberg, Mary E. Delany · 2006 · Elsevier eBooks
  51. Altered expression of genes associated with telomere maintenance and cell function of human vascular endothelial cell at elevated temperature
    Toyoki Maeda, Jing-Zhi Guan, Masamichi Koyanagi, Naoki Makino · 2014 · Molecular and Cellular Biochemistry
  52. Chromosome end protection becomes even more complex
    Jan Karlseder · 2009 · Nature Structural & Molecular Biology
  53. Contributions of Telomere Biology to Human Age-Related Disease
    Ting-Lin Yang, Shufei Song, F Brad Johnson · 2015 · Elsevier eBooks
  54. The INK4A/Arf Network — Cell Cycle Checkpoint or Emergency Brake?
    Ana Gutierrez del Arroyo, Gordon G. Peters · 2005 · Advances in experimental medicine and biology
  55. Loss of p21Sdi1 expression in senescent cells after DNA damage accompanied with increase of miR-93 expression and reduced p53 interaction with p21Sdi1 gene promoter
    Ok Ran Choi, In Kyoung Lim · 2011 · Biochemical and Biophysical Research Communications
  56. 2D gel electrophoresis reveals dynamics of t-loop formation during the cell cycle and t-loop in maintenance regulated by heterochromatin state
    Zepeng Zhang, Tianpeng Zhang, Yuanlong Ge, Mengfan Tang, Wenbin Ma, Qinfen Zhang, Shengzhao Gong, Woodring Erik Wright, Jerry W. Shay, Haiying Liu et al. · 2019 · Journal of Biological Chemistry
  57. Alterations in the telomere length distribution and the subtelomeric methylation status in human vascular endothelial cells under elevated temperature in culture condition
    Toyoki Maeda, Jing-Zhi Guan, Masamichi Koyanagi, Naoki Makino · 2013 · Aging Clinical and Experimental Research
  58. Computationally Designed Peptide Inhibitors of the Ubiquitin E3 Ligase SCFFbx4
    Junglim Lee, Deanne W. Sammond, Zeno Fiorini, Jonel P. Saludes, Michael G. Resch, Bing Hao, Wei Wang, Hang Hubert Yin, Xuedong Liu · 2013 · ChemBioChem
  59. Growth defects in mouse telomerase RNA-deficient cells expressing a template-mutated mouse telomerase RNA
    Delphine Tamara Marie-Egyptienne, Marie Eve Brault, Graeme A. M. Nimmo, Arturo Londoño‐Vallejo, Chantal Autexier · 2008 · Cancer Letters
  60. Uncoupling of telomere length and radiosensitivity in mouse lymphoma cell lines of similar genetic background
    Carl N. Sprung, Deborah S. P. Davey, Su Kah Goh, Ian R. Radford, Michael Jerome McKay · 2007 · International Journal of Radiation Biology
  61. Manipulating mouse telomeres: models of tumorigenesis and aging
    Z. Xin, Dominique Broccoli · 2004 · Cytogenetic and Genome Research
  62. Pleiotropic effects of melanin pigmentation: haemoparasite infection intensity but not telomere length is associated with plumage morph in black sparrowhawks
    Edmund Rodseth, Petra Sumasgutner, Gareth J. Tate, Johan F. Nilsson, Hannah Watson, Michelle F. Maritz, Robert A. Ingle, Arjun Amar · 2024 · Royal Society Open Science
  63. Human hnRNPA1 reorganizes telomere-bound replication protein A
    Sophie L. Granger, Richa Sharma, Vikas Kaushik, Mortezaali Razzaghi, Masayoshi Honda, Paras Gaur, Divya S. Bhat, Sabryn M. Labenz, Jenna E. Heinen, Blaine A. Williams et al. · 2024 · Nucleic Acids Research
  64. Somatic stem cell aging and malignant transformation – impact on therapeutic application
    Marcela Kuniaková, Lenka Oravcová, Zuzana Varchulová-Nováková, Diana Viglaska, Ľuboš Danišovič · 2015 · Cellular & Molecular Biology Letters
  65. Mating type influences chromosome loss and replicative senescence in telomerase‐deficient budding yeast by Dnl4‐dependent telomere fusion
    Damon H. Meyer, Adam M. Bailis · 2008 · Molecular Microbiology
  66. Nonhomologous DNA End Joining
    Shivangi Sharma, Sathees C. Raghavan · 2015 · Elsevier eBooks
  67. Telomeric dysfunction triggers an unstable growth arrest leading to irreparable genomic lesions and entry into cellular senescence
    Sabrina Ghadaouia, Marc‐Alexandre Olivier, Aurélie Martinez, Nicolas Malaquin, Guillaume B. Cardin, Françis Rodier · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  68. Induced Pluripotent Stem Cell-Derived Fibroblasts Efficiently Engage Senescence Pathways but Show Increased Sensitivity to Stress Inducers
    Marie‐Lyn Goyer, Cynthia Désaulniers-Langevin, Anthony Sonn, Georgio Mansour Nehmo, Véronique Lisi, Basma Benabdallah, Noël J.‐M. Raynal, Christian M. Beausejour · 2024 · Cells
  69. Pathology of Aging Skin
    Qunshan Jia, J. Frank Nash · 2009 · Springer eBooks
  70. Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells
    Alexander P. Sobinoff, Salvatore Di Maro, Ronnie Ren Jie Low, Rosaria Benedetti, Stefano Tomassi, Antonia D’Aniello, Rosita Russo, Ilaria Baglivo, Ugo Chianese, Paolo V. Pedone et al. · 2023 · Cell chemical biology
  71. Aging and bone
    Maria Almeida, Stavros C. Manolagas · 2019 · Elsevier eBooks
  72. Telomere Dysfunction in Renal Tubular Epithelial Cells Leads to Kidney Fibrosis
    Sarita Saraswati, Paula Martínez, Rosa Serrano, Diego Megı́as, Osvaldo Graña‐Castro, Ruth Álvarez, Juana María Flores, Marı́a A. Blasco · 2025 · Journal of the American Society of Nephrology
  73. A Comparison of Senescence in Mouse and Human Cells
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  74. Pathology of Aging Skin
    Qunshan Jia, J. Frank Nash · 2016 · Springer eBooks
  75. Acute telomere deprotection prevents ongoing BFB cycles and rampant instability in p16INK4a-deficient epithelial cells
    Aina Bernal, Marc Moltó‐Abad, Daniel Domínguez, Laura Tusell · 2018 · Oncotarget
  76. Telomere stability and carcinogenesis: an off-again, on-again relationship
    Jennifer J. Wanat, F Brad Johnson · 2012 · Journal of Clinical Investigation
  77. Murine Models of Dysfunctional Telomeres and Telomerase
    Yie Liu, Lea A. Harrington · 2012 · Wiley eBooks
  78. Polyploidy in Animal Development and Disease
    Jennifer L. Bandura, Norman Zielke · 2017 · Wiley eBooks
  79. Telomere C-Strand Fill-In Machinery: New Insights into the Human CST-DNA Polymerase Alpha-Primase Structures and Functions
    Ci Ji Lim · 2024 · Sub-cellular biochemistry/Subcellular biochemistry
  80. The role of senescence in cancer therapy-associated cardiovascular toxicity
    Yasmin K. Alshoubaki, Vivienne Grüterich, Valentina Zollet, Gabriela M. Kuster · 2024 · The Journal of Cardiovascular Aging
  81. An immunocompetent murine model of virus-elicited liver fibrosis and hepatocellular carcinoma
    Mariana Nogueira Batista, Juliano Bordignon, Ana Luiza Pamplona Mosimann, Tesia Bobrowski, Hsuan-An Chen, Gabriel Tobin-Xet, Erika A. Barrall, Nataliya Prokhnevska, Abishek Balachandra Vaidya, Tyler Lewy et al. · 2026 · Journal of Hepatology
  82. The ARF protein in tumor suppression: lessons from mouse models and human tumors
    Ignacio Palmero Rodríguez · 2004 · Clinical & Translational Oncology
  83. Effects of Physical Activity, Exercise Training and Physical Fitness on Telomere Length as Biomarker of Cell Aging
    Yun‐A Shin, Changsun Kim, Dong‐Ho Park · 2018 · Exercise Science
  84. Effects of HSV-G47Δ Oncolytic Virus on Telomerase and Telomere Length Alterations in Glioblastoma Multiforme Cancer Stem Cells Under Hypoxia and Normoxia Conditions
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  86. Telomere-Based Cancer Treatment
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  87. Effects of aqueous extract of Salvia officinalis on some parameters of sperms and histopathological changes in testes of rats treated with Doxorubicin
    Khalid M. Alsyaad · 2014 · Egyptian Academic Journal of Biological Sciences. B, Zoology
  88. Overview of DNA Repair Pathways
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  89. Telomeres and Telomerase: Distinctive Roles in Liver Regeneration, Cirrhosis and Carcinogenesis
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  90. Mouse models of human B lymphoid neoplasms
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  91. Alternative Lengthening of Telomeres in Human Cells
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  92. Suppression of genomic instability by replicative senescence and crisis
    Jan Karlseder · 2020 · Genome Instability & Disease
  93. Telomere Dysfunction Drives Chronic Lung Allograft Dysfunction Pathology
    Ram Prasad Naikawadi, Gary Green, Kirk D. Jones, Natalia Achtar‐Zadeh, Julia E. Mieleszko, Jasleen Kukreja, John R. Greenland, Paul J. Wolters · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  94. Telomerase Prevents Emphysema in Old Mice by Sustaining Subpopulations of Endothelial and AT2 Cells
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  95. Exploring the impact of metformin on testicular aging in Syrian hamsters
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  96. Stratification of telomerase activity in cancer reveals associations with senescence and genomic instability
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  97. Reduced CHMP7 Expression Compromises Telomere Integrity in Mammalian Cells
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  98. Telomeric Damage in Aging
    Thomas von Zglinicki · 2003 · Springer eBooks
  99. Cellular Senescence and Its Relation with Telomere
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  100. Telomeres and Brain Tumors
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