Different telomere damage signaling pathways in human and mouse cells

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Items 201–300 of 480

1. Immortalization of Primary Keratinocytes and Its Application to Skin Research
   Moonju Choi, Choong-Ho Lee · 2015 · Biomolecules & Therapeutics
2. Telomerase inhibitors and ‘T-oligo’ as cancer therapeutics: contrasting molecular mechanisms of cytotoxicity
   Andrew M. Rankin, Douglas V. Faller, Remco A. Spanjaard · 2008 · Anti-Cancer Drugs
3. Sister telomeres rendered dysfunctional by persistent cohesion are fused by NHEJ
   Susan Jean Hsiao, Susan Harless Smith · 2009 · The Journal of Cell Biology
4. Signaling pathway requirements for induction of senescence by telomere homolog oligonucleotides
   Guang‐Zhi Li, Mark S. Eller, Kendra Hanna, Barbara A. Gilchrest · 2004 · Experimental Cell Research
5. FOXA1 mediates p16INK4a activation during cellular senescence
   Qian Li, Yu Zhang, Jingxuan Fu, Limin Han, Lixiang Xue, Cuicui Lv, Pan Wang, Guodong Li, Tanjun Tong · 2013 · The EMBO Journal
6. Telomere Length Analysis
   Andrés Canela, Peter Klatt, Marı́a A. Blasco · 2007 · Methods in molecular biology
7. p16INK4a protects against dysfunctional telomere–induced ATR-dependent DNA damage responses
   Yang Wang, Norman E. Sharpless, Sandy S. Chang · 2013 · Journal of Clinical Investigation
8. Molecular mechanisms and cardiovascular implications of cancer therapy-induced senescence
   Ibrahim Y. Abdelgawad, Karim Thomas Sadak, Diana W. Lone, Mohamed S. Dabour, Laura J. Niedernhofer, Beshay N. M. Zordoky · 2020 · Pharmacology & Therapeutics
9. Phosphorylation of p16 Correlates with Cdk4 Association
   Jay Gump, David Stokoe, Frank P. McCormick · 2003 · Journal of Biological Chemistry
10. Mesenchymal stem cells: From stem cells to sarcomas
    Kwan Liang Lye, Norshariza Nordin, Sharmili Vidyadaran, Karuppiah Thilakavathy · 2016 · Cell Biology International
11. Pharmacological intervention strategies for affecting telomerase activity: Future prospects to treat cancer and degenerative disease
    Ilona Tárkányi, János Aradi · 2007 · Biochimie
12. Human mesenchymal stem cells with enhanced telomerase activity acquire resistance against oxidative stress-induced genomic damage
    Varvara Trachana, Spyros Petrakis, Zisis Fotiadis, Evangelia K. Siska, Vasileios Balis, Efstathios S. Gonos, Martha G. Kaloyianni, George Koliakos · 2017 · Cytotherapy
13. Protection against chromosome degradation at the telomeres
    Nathalie Grandin, Michel Charbonneau · 2007 · Biochimie
14. p14ARF is a component of the p53 response following ionizing irradiation of normal human fibroblasts
    Shireen Hussain Khan, Claudia I. Guevara, Greg Fujii, David Parry · 2004 · Oncogene
15. TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence
    Lucy Cassar, Craig Nicholls, Alexander Ruvantha Pinto, Ruping Chen, Lihui Wang, He Li, Junping Liu · 2016 · Protein & Cell
16. Progenitor cell niche senescence reflects pathology of the parotid salivary gland in primary Sjögren’s syndrome
    Xiaoyan Wang, Hendrika Bootsma, Janneke H. Terpstra, Arjan Vissink, Bert van der Vegt, Fred K. L. Spijkervet, Frans G. M. Kroese, Sarah A. Pringle · 2020 · Rheumatology
17. DSB repair pathway choice is regulated by recruitment of 53BP1 through cell cycle-dependent regulation of Sp1
    Michelle L. Swift, Kate Beishline, Samuel P. Flashner, Jane Azizkhan‐Clifford · 2021 · Cell Reports
18. Functional Diversity of Human Protection of Telomeres 1 Isoforms in Telomere Protection and Cellular Senescence
    Qin Yang, Ran Zhang, Izumi Horikawa, Kaori Fujita, Yalda Afshar, Antti Kokko, Päivi Laiho, Lauri A. Aaltonen, Curtis C. Harris · 2007 · Cancer Research
19. Role of telomeres in vascular senescence
    Tohru Minamino · 2007 · Frontiers in bioscience
20. Conserved genes and pathways in primary human fibroblast strains undergoing replicative and radiation induced senescence
    Marthandan, Shiva, Menzel, Uwe, Priebe, Steffen, Groth, Marco, Guthke, Reinhard, Platzer, Matthias, Hemmerich, Peter, Kaether, Christoph, Diekmann, Stephan · 2016 · Biological Research
21. TRF2 dysfunction elicits DNA damage responses associated with senescence in proliferating neural cells and differentiation of neurons
    Peisu Zhang, Katsutoshi Furukawa, Patricia Lynn Opresko, X.Z. Shawn Xu, Vilhelm A. Bohr, Mark P. Mattson · 2006 · Journal of Neurochemistry
22. New dimeric carbazole–benzimidazole mixed ligands for the stabilization of human telomeric G-quadruplex DNA and as telomerase inhibitors. A remarkable influence of the spacer
    Basudeb Maji, Krishan Kumar, Kalappa Muniyappa, Santanu Bhattacharya · 2015 · Organic & Biomolecular Chemistry
23. Characterization of the DNA binding specificity of Shelterin complexes
    Kyung H. Choi, Amy S. Farrell, Amanda S. Lakamp, Michel M. Ouellette · 2011 · Nucleic Acids Research
24. DNA Polymerase β Interacts with TRF2 and Induces Telomere Dysfunction in a Murine Mammary Cell Line
    Poppy P. Fotiadou, Octavian Henegariu, Joann Balazs Sweasy · 2004 · Cancer Research
25. Genetic interrogation of replicative senescence uncovers a dual role for USP28 in coordinating the p53 and GATA4 branches of the senescence program
    Mazzucco, Anna E., Smogorzewska, Agata, Kang, Chanhee, Luo, Ji, Schlabach, Michael R., Xu, Qikai, Patel, Rupesh, Elledge, Stephen J. · 2017 · Genes & Development
26. Transient induction of telomerase expression mediates senescence and reduces tumorigenesis in primary fibroblasts
    Linlin Sun, Jeffrey Y. Chiang, Ji Young Choi, Zheng‐Mei Xiong, Xiaojing Mao, Francis S. Collins, Richard J. Hodes, Kan Cao · 2019 · Proceedings of the National Academy of Sciences
27. Aging and the programmed death phenomena
    Vladimir P. Skulachev · 2003 · Topics in current genetics
28. Mechanism of the Antiproliferative Activity of Some Naphthalene Diimide G-Quadruplex Ligands
    Sonja M. Hampel, Antonella Pepe, Karin M. Greulich‐Bode, Sanjay V. Malhotra, Anthony P. Reszka, Sebastian Veith, Petra Boukamp, Stephen Neidle · 2012 · Molecular Pharmacology
29. TRF2 Mediates Replication Initiation within Human Telomeres to Prevent Telomere Dysfunction
    William C. Drosopoulos, Zhong Deng, Shyam Twayana, Settapong T Kosiyatrakul, Olga V. Vladimirova, Paul M. Lieberman, Carl L. Schildkraut · 2020 · Cell Reports
30. p16INK4a: A central player in cellular senescence and a promising aging biomarker in elderly cancer patients
    Bert Vandenberk, Barbara Anna Henk Brouwers, Sigrid Hatse, Hans P. M. W. Wildiers · 2011 · Journal of Geriatric Oncology
31. Bone Morphogenetic Protein-7 Inhibits Telomerase Activity, Telomere Maintenance, and Cervical Tumor Growth
    Lucy Cassar, He Li, Alexander Ruvantha Pinto, Craig Nicholls, Sharyn Bayne, Junping Liu · 2008 · Cancer Research
32. AtTRB1, a telomeric DNA-binding protein from Arabidopsis, is concentrated in the nucleolus and shows highly dynamic association with chromatin
    Martina Dvořáčková, Pascale Rossignol, Peter Shaw, Olga Koroleva, John H. Doonan, Jiřı́ Fajkus · 2009 · The Plant Journal
33. Minimizing the risk of cancer: tissue architecture and cellular replication limits
    Ignacio A. Rodriguez-Brenes, Dominik Wodarz, Natalia L. Komarova · 2013 · Journal of The Royal Society Interface
34. Up-regulation of telomere-binding TRF1, TRF2 related to reactive oxygen species induced by As2O3 in MGC-803 cells
    Yan Zhang, En‐Hua Cao, Jing‐Fen Qin · 2005 · European Journal of Pharmacology
35. Aging: past, present and future
    Mikhail V. Blagosklonny, Judith Campisi, David A. Sinclair · 2009 · Aging
36. Senescing oral dysplasias are not immortalized by ectopic expression of hTERT alone without other molecular changes, such as loss of INK4A and/or retinoic acid receptor-β: but p53 mutations are not necessarily required
    Alessandra Muntoni, Janis Fleming, Katrina Gordon, Keith David Hunter, Fiona McGregor, Eric Kenneth Parkinson, Paul R. Harrison · 2003 · Oncogene
37. The Connection Between Cell Fate and Telomere
    Ayşe Başak Engin, Atilla Engin · 2021 · Advances in experimental medicine and biology
38. Telomerase inhibition is an effective therapeutic strategy in TERT promoter-mutant glioblastoma models with low tumor volume
    Elisa Aquilanti, Lauren Kageler, Jacqueline Watson, Duncan M. Baird, Rhiannon E. Jones, Marie Hodges, Zsofia M Szegletes, John G. Doench, Craig A. Strathdee, Jose Ricardo McFaline-Figueroa et al. · 2023 · Neuro-Oncology
39. Degradation of p53, Not Telomerase Activation, by E6 Is Required for Bypass of Crisis and Immortalization by Human Papillomavirus Type 16 E6/E7
    Helene R. McMurray, Dennis J. McCance · 2004 · Journal of Virology
40. Activation of Mrc1, a mediator of the replication checkpoint, by telomere erosion
    Nathalie Grandin, Aymeric Bailly, Michel Charbonneau · 2005 · Biology of the Cell
41. Those dam-aged telomeres!
    Lea A. Harrington · 2003 · Current Opinion in Genetics & Development
42. Role of senescence and mitotic catastrophe in cancer therapy
    Richa Singh, Jasmine George, Yogeshwer Shukla · 2010 · Cell Division · Retracted
43. Telomere shortening and DNA damage in culprit cells of different types of progressive fibrosing interstitial lung disease
    Aernoud A. van Batenburg, Karin M. Kazemier, Matthijs F.M. van Oosterhout, Joanne J. van der Vis, Jan C. Grutters, Roel Goldschmeding, Coline H.M. van Moorsel · 2021 · ERJ Open Research
44. The Telomere–Telomerase Axis and the Heart
    Jan Kajstura, Marcello Rota, Konrad Urbanek, Toru Hosoda, Claudia Bearzi, Piero Anversa, Roberto Bolli, Annarosa Leri · 2006 · Antioxidants and Redox Signaling
45. MDL-1, a growth- and tumor-suppressor, slows aging and prevents germline hyperplasia and hypertrophy in C. elegans
    Michèle Riesen, Inna Feyst, Nattaphong Rattanavirotkul, Marina Ezcurra, Jennifer M. A. Tullet, Irene Papatheodorou, Matthias Ziehm, Catherine Au, Ann F. Gilliat, Josephine E. E. U. Hellberg et al. · 2014 · Aging
46. Dynamics of telomere erosion in transformed and non-transformed avian cells in vitro
    Susan E. Swanberg, Mary E. Delany · 2003 · Cytogenetic and Genome Research
47. Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response
    Jullien, Laurent, Mestre, Marie, Roux, Pierre, Gire, Véronique · 2013 · Nucleic Acids Research
48. Transcriptomic Analysis of Cellular Senescence: One Step Closer to Senescence Atlas
    Sohee Kim, Chuna Kim · 2021 · Molecules and Cells
49. Increase in lamin B1 promotes telomere instability by disrupting the shelterin complex in human cells
    Gaëlle Pennarun, Julien Picotto, Laure Etourneaud, Anna Rita Redavid, Anaïs Certain, Laurent Gauthier, Paula Fontanilla-Ramirez, Didier Busso, Caroline Chabance-Okumura, Benoît Thezé et al. · 2021 · Nucleic Acids Research
50. Novel Antitumor and Neuroprotective Substances Discovered by Characteristic Screenings Based on Specific Molecular Targets
    Kazuo Shin‐ya · 2005 · Bioscience Biotechnology and Biochemistry
51. Different requirements of functional telomeres in neural stem cells and terminally differentiated neurons
    Anastasia Lobanova, Robert She, Simon Pieraut, Charlie Clapp, Anton Maximov, Eros Lazzerini Denchi · 2017 · Genes & Development
52. Anti-senescence effect and molecular mechanism of the major royal jelly proteins on human embryonic lung fibroblast (HFL-I) cell line
    Chenmin Jiang, Xin Liu, Chunxue Li, Hao-cheng Qian, Di Chen, Chao‐Qiang Lai, Lirong Shen · 2018 · Journal of Zhejiang University SCIENCE B
53. Dyskerin, telomerase and the DNA damage response
    Bai-Wei Gu, Monica Bessler, Philip J. Mason · 2009 · Cell Cycle
54. The telomerase cycle: normal and pathological aspects
    Michèle Brunori, Pierre Luciano, Éric Gilson, Vincent G�li · 2005 · Journal of Molecular Medicine
55. The TP53 Dependence of Radiation-Induced Chromosome Instability in Human Lymphoblastoid Cells
    Jeffrey L. Schwartz, Robert T. Jordan, Helen H. Evans, Marek Lenarczyk, Howard L. Liber · 2003 · Radiation Research
56. p16 Is upregulated in proliferative inflammatory atrophy of the prostate
    Dennis Faith, Steven Han, Daniel K. Lee, Andreas Friedl, Jessica L Hicks, Angelo Michael De Marzo, David Frazier Jarrard · 2005 · The Prostate
57. Telomere dysfunction and loss of p53 cooperate in defective mitotic segregation of chromosomes in cancer cells
    Milena Pantić, Stefan Zimmermann, Hesham El Daly, O. G. OPITZ, Susanne Popp, Petra Boukamp, Uwe M. Martens · 2006 · Oncogene
58. Dual roles of telomere dysfunction in initiation and suppression of tumorigenesis
    Wilfredo Cosme‐Blanco, Sandy S. Chang · 2008 · Experimental Cell Research
59. Mechanisms That Limit the In Vitro Proliferative Potential of Human CD8+ T Lymphocytes
    Marco Migliaccio, Kenneth Raj, Olivier Menzel, Nathalie Rufer · 2005 · The Journal of Immunology
60. Functions of ADP-ribose transferases in the maintenance of telomere integrity
    Daniela Muoio, Natalie Laspata, Elise Fouquerel · 2022 · Cellular and Molecular Life Sciences
61. RSK4 inhibition results in bypass of stress-induced and oncogene-induced senescence
    Laura López-Vicente, B. Pons, Laura Coch, Cristina Teixidó, Javier Hernández‐Losa, Gemma Armengol, Santiago Ramón y Cajal · 2011 · Carcinogenesis
62. Telomeric recombination induced by dysfunctional telomeres
    Marie Eve Brault, Chantal Autexier · 2010 · Molecular Biology of the Cell
63. TRF2 inhibition promotes anchorage-independent growth of telomerase-positive human fibroblasts
    Michèle Brunori, Noëlle Mathieu, Michelle Ricoul, Serge Bauwens, Catherine Koering, Aude Roborel de Climens, Aurélie Belleville, Q Wang, Isabelle Puisieux, Didier Décimo et al. · 2005 · Oncogene
64. Cellular senescence, telomere recombination and maintenance
    Qin Yang · 2008 · Cytogenetic and Genome Research
65. Ras Regulates Rb via NORE1A
    Thibaut Barnoud, Howard Donninger, Geoffrey J. Clark · 2015 · Journal of Biological Chemistry
66. Condensin II subunit NCAPH2 associates with shelterin protein TRF1 and is required for telomere stability
    Heather A. Wallace, Vibhuti Rana, Huy Q. Nguyen, Giovanni Bosco · 2019 · Journal of Cellular Physiology
67. Telomere dysfunction is related to the intrinsic radio-resistance of human oral cancer cells
    James Anthony McCaul, Katrina Gordon, Fay Minty, Janis Fleming, Eric Kenneth Parkinson · 2007 · Oral Oncology
68. Arrested development and the great escape – The role of cellular senescence in pancreatic cancer
    John A. G. Moir, Steven Alan White, Jelena Mann · 2014 · The International Journal of Biochemistry & Cell Biology
69. Airway Epithelial Telomere Dysfunction Drives Remodeling Similar to Chronic Lung Allograft Dysfunction
    Ram Prasad Naikawadi, Gary Green, Kirk D. Jones, Natalia Achtar‐Zadeh, Julia E. Mieleszko, Isabel S Arnould, Jasleen Kukreja, John R. Greenland, Paul J. Wolters · 2020 · American Journal of Respiratory Cell and Molecular Biology
70. Loss of p16Ink4a Function Rescues Cellular Senescence Induced by Telomere Dysfunction
    Zhang, Xiufeng, Wu, Xiaoming, Tang, Wenru, Luo, Ying · 2012 · International Journal of Molecular Sciences
71. Role of cellular senescence in hepatic wound healing and carcinogenesis
    Gayatri Ramakrishna, Tarique Anwar, Rajendra Kumar Angara, Nirupama Chatterjee, Shashi Kiran, Sapna Singh · 2012 · European Journal of Cell Biology
72. Long Telomeres Bypass the Requirement for Telomere Maintenance in Human Tumorigenesis
    Michael A. S. Taboski, David Sealey, Jennifer Dorrens, Chandrakant Tayade, Dean Harvey Betts, Lea A. Harrington · 2012 · Cell Reports
73. A gain-of-function senescence bypass screen identifies the homeobox transcription factor DLX2 as a regulator of ATM–p53 signaling
    Yifan Wang, Qikai Xu, Laura Magill Sack, Chanhee Kang, Stephen Joseph Elledge · 2016 · Genes & Development
74. Telomeres, cell senescence and human ageing
    Thomas von Zglinicki, Carmen M. Martin-Ruiz, Gabriele Christine Saretzki · 2005 · Signal Transduction
75. The DNA damage response at dysfunctional telomeres, and at interstitial and subtelomeric DNA double-strand breaks
    Keiko Muraki, John P. Murnane · 2017 · Genes & Genetic Systems
76. CARF: An emerging regulator of p53 tumor suppressor and senescence pathway
    Caroline Cheung, Md Kamrul Hasan, Nashi Widodo, Sunil C. Kaul, Renu Wadhwa · 2008 · Mechanisms of Ageing and Development
77. Oncogenic RAS-induced senescence in human primary thyrocytes: molecular effectors and inflammatory secretome involved
    Maria Grazia Vizioli, Joana Dos Santos, Silvana Pilotti, Mara Mazzoni, Maria Chiara Anania, Claudia Miranda, Sonia Pagliardini, Marco Alessandro Pierotti, Jesús Gil, Angela Greco · 2014 · Oncotarget
78. 5′ C-rich telomeric overhangs are an outcome of rapid telomere truncation events
    Liana Oganesian, Jan Karlseder · 2013 · DNA repair
79. A 6-mer Photocontrolled Oligonucleotide as an Effective Telomerase Inhibitor
    Yan Xu, Kenichiro Ito, Yuta Suzuki, Makoto Komiyama · 2009 · Journal of the American Chemical Society
80. Ascorbic acid extends replicative life span of human embryonic fibroblast by reducing DNA and mitochondrial damages
    Hwang, Won-Sang, Park, Seong-Hoon, Kim, Hyun-Seok, Kang, Hong-Jun, Kim, Min-Ju, Oh, Soo-Jin, Park, Jae-Bong, Kim, Jaebong, Kim, Sung Chan, Lee, Jae-Yong · 2007 · Nutrition Research and Practice
81. Association of a Platinum Complex to a G-Quadruplex Ligand Enhances Telomere Disruption
    Razan Charif, Christine Granotier-Beckers, Hélène Charlotte Bertrand, Joël Poupon, Evelyne Ségal-Bendirdjian, Marie‐Paule Teulade‐Fichou, François Dominique Boussin, Sophie Bombard · 2017 · Chemical Research in Toxicology
82. Une re-vue de la sénescence cellulaire
    Oliver Bischof, Anne Dejean, Pascal Pineau · 2009 · médecine/sciences
83. High Mobility Group A2 protects cancer cells against telomere dysfunction
    Suchitra Natarajan, Farhana Begum, Jeonga Gim, Landon Wark, Dana Henderson, James Davie, Sabine Hombach‐Klonisch, Thomas C. Klonisch · 2016 · Oncotarget
84. Cell cycle arrest in replicative senescence is not an immediate consequence of telomere dysfunction
    M.Shamim Nassrally, Ashley Lau, Katherine Wise, Noah John, Sanjeev Kotecha, Kar Lai Lee, Robert F. Brooks · 2019 · Mechanisms of Ageing and Development
85. Immortalized cells as experimental models to study cancer
    Jesse S. Boehm, William C. Hahn · 2004 · Cytotechnology
86. Knockdown of Telomerase RNA Using Hammerhead Ribozymes and RNA Interference
    Shang Li, Mehdi Nosrati, Mohammed Kashani–Sabet · 2007 · Methods in molecular biology
87. Stem cell ageing: does it happen and can we intervene?
    Ilaria Bellantuono, W. Nicol Keith · 2007 · Expert Reviews in Molecular Medicine
88. Targeting Telomerase
    Aisha Siddiqa, David Cavazos, Robert A. Marciniak · 2006 · Rejuvenation Research
89. Making the most of a little: dosage effects in eukaryotic telomere length maintenance
    Lea A. Harrington · 2005 · Chromosome Research
90. The Presence of Telomere Fusion in Sporadic Colon Cancer Independently of Disease Stage, TP53/KRAS Mutation Status, Mean Telomere Length, and Telomerase Activity
    Tanaka, Hiromi, Beam, Matthew J., Caruana, Kevin · 2014 · Neoplasia
91. Enhanced proliferation of human skeletal muscle precursor cells derived from elderly donors cultured in estimated physiological (5%) oxygen
    Sheree D. Martin, Fiona Collier, Mark A. Kirkland, Ken R. Walder, Nicole Stupka · 2009 · Cytotechnology
92. A Link between Replicative Stress, Lamin Proteins, and Inflammation
    Simon Willaume, Emilie Rass, Paula Fontanilla-Ramirez, Angela Moussa, Paul Wanschoor, Pascale Bertrand · 2021 · Genes
93. Total Deletion of in Vivo Telomere Elongation Capacity: An Ambitious but Possibly Ultimate Cure for All Age‐Related Human Cancers
    Aubrey D.N.J. de Grey, F C Campbell, Inderjeet S Dokal, LJ Fairbairn, Gerard J. Graham, Colin A.B. Jahoda, ANDREW C. G. PORTERG · 2004 · Annals of the New York Academy of Sciences
94. ssDNA fragments induce cell senescence by telomere uncapping
    Tsolou, Avgi, Passos, João F., Nelson, Glyn, Arai, Yasumichi, Zglinicki, Thomas von · 2008 · Experimental Gerontology
95. Role of Telomere Dysfunction in Genetic Intratumor Diversity
    Anna Genescà, Judit Pampalona, Cristina Frías-López, Daniel Domínguez, Laura Tusell · 2011 · Advances in cancer research
96. Model Systems for Examining Effects of Leukemia Associated Oncogenes in Primary Human CD34+ Cells via Retroviral Transduction
    Mark Wunderlich, James C. Mulloy · 2009 · Methods in molecular biology
97. Immortalization of Epstein–Barr virus‐negative human B lymphocytes with minimal chromosomal instability
    Yoriko Yamashita, Tatsuya Tsurumi, Naoyoshi Mori, Tohru Kiyono · 2006 · Pathology International
98. The induction of the fibroblast extracellular senescence metabolome is a dynamic process
    Emma Naomi James, Mark H. Bennett, Eric Kenneth Parkinson · 2018 · Scientific Reports
99. Association of telomere instability with senescence of porcine cells
    Guangzhen Ji, Kai Liu, Maja Okuka, Na Liu, Lin Liu · 2012 · BMC Cell Biology
100. Telomerase as a novel and potentially selective target for cancer chemotherapy
     Eric Kenneth Parkinson · 2003 · Annals of Medicine