The DOI matches its Crossref record; 85 of the 85 references it cites were found in a registry or an index.
Effects of tobacco cigarettes, e-cigarettes, and waterpipe smoking on endothelial function and clinical outcomes
Open accessAbstract
Tobacco smoking is a leading cause of non-communicable disease globally and is a major risk factor for cardiovascular disease (CVD) and lung disease. Importantly, recent data by the World Health Organizations (WHO) indicate that in the last two decades global tobacco use has significantly dropped, which was largely driven by decreased numbers of female smokers. Despite such advances, the use of e-cigarettes and waterpipes (shisha, hookah, narghile) is an emerging trend, especially among younger generations. There is growing body of evidence that e-cigarettes are not a harm-free alternative to tobacco cigarettes and there is considerable debate as to whether e-cigarettes are saving smokers or generating new addicts. Here, we provide an updated overview of the impact of tobacco/waterpipe (shisha) smoking and e-cigarette vaping on endothelial function, a biomarker for early, subclinical, atherosclerosis from human and animal studies. Also their emerging adverse effects on the proteome, transcriptome, epigenome, microbiome, and the circadian clock are summarized. We briefly discuss heat-not-burn tobacco products and their cardiovascular health effects. We discuss the impact of the toxic constituents of these products on endothelial function and subsequent CVD and we also provide an update on current recommendations, regulation and advertising with focus on the USA and Europe. As outlined by the WHO, tobacco cigarette, waterpipe, and e-cigarette smoking/vaping may contribute to an increased burden of symptoms due to coronavirus disease 2019 (COVID-19) and to severe health consequences.
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Citations
Cites
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Self-citationRoles of vascular oxidative stress and nitric oxide in the pathogenesis of atherosclerosis
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A Randomized Trial of E-Cigarettes versus Nicotine-Replacement Therapy
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Cited by
An updated overview of e-cigarette impact on human health
Marques, P., Piqueras, L., & Sanz, M.-J. (2021) · Respiratory Research · doi:10.1186/s12931-021-01737-5 · Cited by 470
Cigarette smoking and liver diseases
Marti-Aguado, D., Clemente-Sanchez, A., & Bataller, R. (2022) · Journal of Hepatology · doi:10.1016/j.jhep.2022.01.016 · Cited by 190
Metadata
- Authors
- Münzel, T., Hahad, O., Kuntic, M., Keaney, J. F., Deanfield, J. E., & Daiber, A.
- Venue
- European Heart Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2020-06-25
- Volume
- 41
- Issue
- 41
- Pages
- 4057-4070
- ISSN
- 0195-668X (ISSN-L)
- 1522-9645
- OpenAlex
- W3037368428
- Cited by
- 406
- References
- 85
- FWCI
- 26.52
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- CoChat. (2026). Citation check: Effects of tobacco cigarettes, e-cigarettes, and waterpipe smoking on endothelial function and clinical outcomes. https://app.cochat.ai/papers/10.1093/eurheartj/ehaa460
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- Münzel, T., Hahad, O., Kuntic, M., Keaney, J. F., Deanfield, J. E., & Daiber, A. (2020). Effects of tobacco cigarettes, e-cigarettes, and waterpipe smoking on endothelial function and clinical outcomes. European Heart Journal. https://doi.org/10.1093/eurheartj/ehaa460
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
