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Immune modulation: the key to combat SARS-CoV-2 induced myocardial injury

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Arrhythmogenic cardiomyopathy: the ongoing search for mechanism-driven therapies meets extracellular vesicles

Basso, C., Zaglia, T., & Pilichou, K. (2021) · European Heart Journal · doi:10.1093/eurheartj/ehab512 · Cited by 6 · see citing works

Exosomal microRNAs from PBMCs stimulated with culprit drugs enhanced keratinocyte cell death in Stevens–Johnson syndrome/toxic epidermal necrolysis

Suthumchai, N., Buranapraditkun, S., Thantiworasit, P., Rerknimitr, P., Wongpiyabovorn, J., Khanaruksombat, S., Reantragoon, R., & Klaewsongkram, J. (2023) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.19000 · Cited by 5 · see citing works

Cell-Specific Impacts of Surface Coating Composition on Extracellular Vesicle Secretion

Liu, Y., Pierre, C. J., Joshi, S., Sun, L. J., Li, Y., Guan, J., Favor, J. D. L., & Holmes, C. A. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c03213 · Cited by 5 · see citing works

Exploring the role of exosomes in the pathogenesis and treatment of cardiomyopathies: A comprehensive literature review

Ameer, S. F., Elsaka, M., Kahtoon, S., Kerzabi, R. I., Casu, G., Giordo, R., Zayed, H., & Pintus, G. (2024) · Life Sciences · doi:10.1016/j.lfs.2024.123063 · Cited by 5 · see citing works

End Plate Chondrocyte-Derived Exosomal miR-133a-3p Alleviates Intervertebral Disc Degeneration by Targeting the NF-κB Signaling Pathway through the miR-133a-3p/MAML1 Axis

Li, Q., Guo, R., Zhao, C., Chen, X., Wang, H., & Shen, C. (2025) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.4c00962 · Cited by 5 · see citing works

Inflammasome and ventricular arrhythmogenesis: Pathogenic interplay and potential targets on the horizon

Narducci, M. L., Conte, C., Telesca, A., Liuzzo, G., & Imazio, M. (2025) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2025.05.006 · Cited by 4 · see citing works

Tumor Necrosis Factor-Alpha Induces Proangiogenic Profiling of Cardiosphere-Derived Cell Secretome and Increases Its Ability to Stimulate Angiogenic Properties of Endothelial Cells

Дергилев, К. В., Zubkova, E., Guseva, A., Цоколаева, З. И., Goltseva, Y., Beloglazova, I. B., Ratner, E. I., Andreev, A., Александрович, П. С., Mg, L., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242316575 · Cited by 4 · see citing works

Treatment of hemophilic arthropathy by immunomodulatory extracellular vesicle delivered by liposome hybrid nanoparticles

Wang, D., Chen, W., Chen, J., He, D., Pan, Y., Wang, P., Zeng, Q., Gu, M., Tong, P., Chen, D., et al. (2024) · Bioactive Materials · doi:10.1016/j.bioactmat.2024.05.039 · Cited by 4 · see citing works

Eight‐Year Outcomes of Cardiosphere‐Derived Cells in Single Ventricle Congenital Heart Disease

Hirai, K., Sawada, R., Hayashi, T., Araki, T., Nakagawa, N., Kondo, M., Yasuda, K., Hirata, T., Sato, T., Nakatsuka, Y., et al. (2024) · Journal of the American Heart Association · doi:10.1161/jaha.124.038137 · Cited by 4 · see citing works

Roles of Optineurin and Extracellular Vesicles in Glaucomatous Retinal Cell Loss

Duan, C.-Y., Fan, W., & Chen, F. (2023) · Current Medical Science · doi:10.1007/s11596-023-2730-9 · Cited by 4 · see citing works

Biological Modification of Arrhythmogenic Substrates by Cell-Free Therapeutics

Lin, Y., Miguel‐dos‐Santos, R., & Cingolani, E. (2023) · Heart Lung and Circulation · doi:10.1016/j.hlc.2023.05.016 · Cited by 4 · see citing works

Histological and functional assessment of a Takotsubo cardiomyopathy model established by immobilization stress

Pei, Q., Yang, J., Li, B., Lin, P., Zou, L., Zhang, J., Yin, H., Sun, J., Wang, X., Nevzorova Vera, A., et al. (2024) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.14930 · Cited by 4 · see citing works

A novel exosome-based therapy for post-MI arrhythmias

Cacheux, M., & Akar, F. G. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehac155 · Cited by 4 · see citing works

TDO2‐augmented fibroblasts secrete EVs enriched in immunomodulatory Y‐derived small RNA

Ciullo, A., Peck, K. A., Jones, X. M., Yamaguchi, S., Morris, A. A., Kumar, A. N., Li, L., Lee, J., dos Santos, R. M., Cingolani, E., et al. (2023) · Journal of Extracellular Biology · doi:10.1002/jex2.73 · Cited by 3 · see citing works

Unraveling the aging-reversal potency of stem cell-derived extracellular vesicles in a rat model of premature cardiac senescence

Gomez-Cid, L., Campo-Fonseca, A., Cervera-Negueruela, M., Ocampo, A., Pinto, Á. G., Gil‐Jaurena, J., Suárez-Sancho, S., Fernández‐Avilés, F., & Grigorian-Shamagian, L. (2025) · iScience · doi:10.1016/j.isci.2025.112910 · Cited by 2 · see citing works

Engineering exosomes and their application in cardiovascular field: Bibliometric analysis from 2002 to 2022

Zhang, X., Yang, Z., Jiang, J., Tang, M., Guan, L., Lee, H., Wang, H., & Xu, J. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e18809 · Cited by 2 · see citing works

The ESC Guidelines on cardiac pacing and resynchronization, and the many facets of atrial fibrillation

Crea, F. (2021) · European Heart Journal · doi:10.1093/eurheartj/ehab628 · Cited by 2 · see citing works

A Paradigm Shift: Arrhythmogenic Cardiomyopathy Is an Inflammatory Disease

Ariyaratne, G. H. D. N., Villatore, A., Peretto, G., & Chelko, S. P. (2026) · Cells · doi:10.3390/cells15100868 · Cited by 2 · see citing works

Mesenchymal stem cell-derived small extracellular vesicles loaded with miRNA-4488 alleviate chemotherapy-induced premature ovarian insufficiency via mitigation of apoptosis and oxidative stress

Li, S.-X., Wei, S.-Y., Li, C., Sheng, Y.-L., Liu, Y., & Xu, N. (2025) · Biomaterials Advances · doi:10.1016/j.bioadv.2025.214656 · Cited by 1 · see citing works

Optical mapping: pioneering the frontier of preclinical antiarrhythmic drug evaluation

Li, Y., Zheng, Y., Dong, R., Lin, M., Chen, T., Li, J., (13940), R. Z., Liu, T., Tan, X., Hao, G., et al. (2026) · iScience · doi:10.1016/j.isci.2026.116126 · Cited by 1 · see citing works

New Variant in Placophilin-2 Gene Causing Arrhythmogenic Myocardiopathy

Caimi-Martínez, F., Antoniutti, G., Blanco, R., de la Villa, B. G., Alvarenga, N., Govea-Callizo, N., Torres‐Juan, L., Heine‐Suñer, D., Andreo, J. R., Luengos, D. C., et al. (2022) · Genes · doi:10.3390/genes13050782 · Cited by 1 · see citing works

The challenge of predicting sudden cardiac death: complementary role of risk scores, genetic testing, and clinical judgement

Crea, F. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehac451 · Cited by 1 · see citing works

New avenues in the prevention of sudden cardiac death

Crea, F. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehac277

Y-Derived Small RNA, NT4, Exerts Cardioprotection Through Regulation of the Macrophage ResponsePreprint

Peck, K. A., Ciullo, A., Jones, X. M., Morris, A. A., Li, L., Kumar, A. N., Yamaguchi, S., Lee, J., & Ibrahim, A. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4099021

Extracellular Vesicles for the Treatment of Atrial Fibrillation

Ihara, K., & Sasano, T. (2023) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2023.01.007

A Comprehensive Review of Exosomes with Therapeutic Potential in Cancer and Coeliac Disease

Assainar, F., Thomas, J. G., Saleem, Z., Thekkekara, S., Mammoo, F., & Kallan, N. N. (2024) · Journal of Biosciences and Medicines · doi:10.4236/jbm.2024.123003

Genetic and immunogenetic basis of myocarditis

Caforio, A. L. P., Baritussio, A., Giordani, A. S., Pilichou, K., Iliceto, S., & Marcolongo, R. (2024) · Elsevier eBooks · doi:10.1016/b978-0-12-822951-4.00006-0

Therapeutic Potential of Exosome for Cardiac Arrhythmia: A Systematic Review of Preclinical Evidence

Harsoyo, A., Eri, R. R., Zahrani, S., Balweel, H., & Tafriend, N. A. (2025) · Stem Cell Reviews and Reports · doi:10.1007/s12015-025-10952-2

To the Editor— DNA methylation and the potential role of extracellular vesicles in epilepsy-associated atrial fibrillation

Barile, L., & Schiano, C. (2025) · Heart Rhythm · doi:10.1016/j.hrthm.2025.10.065

Additional file 1 of Y4 RNA fragments from cardiosphere-derived cells ameliorate diabetic myocardial ischemia‒reperfusion injury by inhibiting protein kinase C β-mediated macrophage polarization

Liu, D., Luo, X.-Z., Lu, C.-H., Feng, Y.-Y., Chen, D.-X., Zeng, Z.-Y., & Huang, F. (2024) · Figshare · doi:10.6084/m9.figshare.26027464

Additional file 5 of Single-cell RNA sequencing in donor and end-stage heart failure patients identifies NLRP3 as a therapeutic target for arrhythmogenic right ventricular cardiomyopathy

Fu, M., Hua, X., Shu, S., Xu, X., Zhang, H., Peng, Z., Mo, H., Liu, Y., Chen, X., Yang, Y., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26659372

Additional file 3 of Single-cell RNA sequencing in donor and end-stage heart failure patients identifies NLRP3 as a therapeutic target for arrhythmogenic right ventricular cardiomyopathy

Fu, M., Hua, X., Shu, S., Xu, X., Zhang, H., Peng, Z., Mo, H., Liu, Y., Chen, X., Yang, Y., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26659366

Additional file 1 of Single-cell RNA sequencing in donor and end-stage heart failure patients identifies NLRP3 as a therapeutic target for arrhythmogenic right ventricular cardiomyopathy

Fu, M., Hua, X., Shu, S., Xu, X., Zhang, H., Peng, Z., Mo, H., Liu, Y., Chen, X., Yang, Y., et al. (2024) · Figshare · doi:10.6084/m9.figshare.24956003

Additional file 4 of Single-cell RNA sequencing in donor and end-stage heart failure patients identifies NLRP3 as a therapeutic target for arrhythmogenic right ventricular cardiomyopathy

Fu, M., Hua, X., Shu, S., Xu, X., Zhang, H., Peng, Z., Mo, H., Liu, Y., Chen, X., Yang, Y., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26659369

Additional file 6 of Single-cell RNA sequencing in donor and end-stage heart failure patients identifies NLRP3 as a therapeutic target for arrhythmogenic right ventricular cardiomyopathy

Fu, M., Hua, X., Shu, S., Xu, X., Zhang, H., Peng, Z., Mo, H., Liu, Y., Chen, X., Yang, Y., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26659375

Additional file 7 of Single-cell RNA sequencing in donor and end-stage heart failure patients identifies NLRP3 as a therapeutic target for arrhythmogenic right ventricular cardiomyopathy

Fu, M., Hua, X., Shu, S., Xu, X., Zhang, H., Peng, Z., Mo, H., Liu, Y., Chen, X., Yang, Y., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26659378

Additional file 2 of Single-cell RNA sequencing in donor and end-stage heart failure patients identifies NLRP3 as a therapeutic target for arrhythmogenic right ventricular cardiomyopathy

Fu, M., Hua, X., Shu, S., Xu, X., Zhang, H., Peng, Z., Mo, H., Liu, Y., Chen, X., Yang, Y., et al. (2024) · Figshare · doi:10.6084/m9.figshare.24956203

Extracellular vesicle therapeutics for cardiac regeneration: Overcoming standardization hurdles

Xue, R.-Q., Hou, J., Gao, W.-X., Zhang, L.-H., Liu, Y.-X., & Zhou, X. (2026) · World Journal of Stem Cells · doi:10.4252/wjsc.114716

Bioengineering Approaches for Nanomedicine Delivery in Therapy of Myocardial Infarction

Zou, J., Zhu, D., Cheng, X., & Cheng, K. (2026) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.126.324247

Extracellular Vesicles in Cardiovascular Disease: Intercellular Signaling, Liquid Biopsy Biomarkers, and Therapeutic Translation

Spanos, M., Gokulnath, P., Behera, G., Azzam, C., & Das, S. (2026) · Circulation Research · doi:10.1161/circresaha.126.327198

Noncoding RNA TY1 reverses fibrosis in systemic sclerosis by attenuating the cGAS/STING pathway

Jones, X. M., Soussi, S., Ciullo, A., Tsi, K., Liu, W., Li, L., Fournier, M., Mesquita, T., Marchevsky, A. M., Bottini, N., et al. (2026) · JCI Insight · doi:10.1172/jci.insight.197716

Nanoparticle-Based Targeted Drug-Delivery Systems for Cardiomyopathy: Mechanisms and Therapeutic Advances

Liang, B., Zhang, T., Tang, S., Zhou, X., Xie, S., Jia, Z., Lin, H., Luo, G., & Lin, B. (2026) · Molecules · doi:10.3390/molecules31173137

Arrhythmogenic cardiomyopathy: the ongoing search for mechanism-driven therapies meets extracellular vesicles

Basso, C., Zaglia, T., & Pilichou, K. (2021) · European Heart Journal · doi:10.1093/eurheartj/ehab512 · Cited by 6 · see citing works

Abstract P3093: Early Myocarditis In The Desmoglein 2 Mutant Mouse Model Of Arrhythmogenic Cardiomyopathy

Valdez, S., Taylor, L., Rosenzweig, R., Bansal, S. S., & Palatinus, J. A. (2023) · Circulation Research · doi:10.1161/res.133.suppl_1.p3093

Abstract 15358: Deletion of Csf2 Accelerates Disease Progression in a Mouse Model of Arrhythmogenic Cardiomyopathy

Chelko, S. P., Penna, V. R., Engel, M., Landim-Vieira, M., Centner, A. M., Cannon, E. N., Lavine, K. J., & Saffitz, J. E. (2023) · Circulation · doi:10.1161/circ.148.suppl_1.15358

Suppression of Early Inflammatory Response in a Murine Model of Arrhythmogenic Cardiomyopathy Accelerates Cardiac Fibrosis and Heart FailurePreprint

Ng, K., Delaney, P. J., Thenet, D., Murtough, S., Webb, C., Pink, R. C., Marelli‐Berg, F. M., Kelsell, D. P., & Tinker, A. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.4892928

Early cardiac inflammation as a driver of murine model of Arrhythmogenic CardiomyopathyPreprint

Ng, K., Delaney, P. J., Thenet, D., Murtough, S., Webb, C. M., Tsisanova, E., Walker, S. L. M., Westaby, J. D., Pennington, D. J., Pink, R. C., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.06.24.169664 · Cited by 1 · see citing works