The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
2023 Focused Update of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure
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The findings were first benchmarked against results from the STEP-HFpEF DM and SUMMIT trials.
“these findings were first benchmarked against results from the STEP-HFpEF DM and SUMMIT trials.9-11,55”
From Semaglutide and Tirzepatide in Patients With Heart Failure With Preserved Ejection Fraction (2025) · cites this paper as [9]
The Chronic heart failure section discusses results from EMPEROR-Preserved and DELIVER, but does not describe benchmarking findings against STEP-HFpEF DM or SUMMIT. Searches of our full-text copy for both trial names and for the proposed benchmarking found no passage addressing it; the paper’s discussion of other trials does not establish that the benchmarking occurred. (LLM, conf=0.76)
Experimental — accuracy not yet measuredGuideline committees withheld formal recommendations for semaglutide and tirzepatide in HFpEF pending confirmation of benefits on clinical outcomes.
“Similarly, guideline committees withheld formal recommendations pending confirmation of benefits on clinic al outcomes to complement these trial findings.9-12”
From Semaglutide and Tirzepatide in Patients With Heart Failure With Preserved Ejection Fraction (2025) · cites this paper as [9]
Section 3 (Chronic heart failure; page unavailable) discusses recommendations for other HFpEF therapies, including SGLT2 inhibitors, but does not address withholding recommendations for semaglutide or tirzepatide pending clinical-outcome evidence. Searches for both drug names and related recommendation language found no passage addressing that claim. (LLM, conf=0.76)
Experimental — accuracy not yet measuredRegulatory agencies and guideline committees have emphasized the need for further evidence for major clinical outcomes in heart failure.
“Because regulatory agencies and guideline committees have emphasized the need for further evidence for major clinical outcomes in heart failure”
From Semaglutide and Tirzepatide in Patients With Heart Failure With Preserved Ejection Fraction (2025) · cites this paper as [9]
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Cites
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Self-citationEmpagliflozin in heart failure with a preserved ejection fraction
Anker, S. D., Butler, J., Filippatos, G., Ferreira, J. P., Bocchi, E., Böhm, M., Brunner–La Rocca, H.-P., Choi, D.-J., Chopra, V., Chuquiure-Valenzuela, E., et al. (2021) · New England Journal of Medicine · doi:10.1056/nejmoa2107038 · Cited by 4,874
Self-citationEffect of finerenone on chronic kidney disease outcomes in type 2 diabetes
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Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction
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Self-citationEmpagliflozin in Patients with Chronic Kidney Disease
The EMPA-KIDNEY Collaborative Group (2023) · New England Journal of Medicine · doi:10.1056/nejmoa2204233 · Cited by 2,754
Ferric Carboxymaltose in Patients with Heart Failure and Iron Deficiency
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Self-citationSotagliflozin in patients with diabetes and recent worsening heart failure
Bhatt, D. L., Szarek, M., Steg, P. G., Cannon, C. P., Leiter, L. A., McGuire, D. K., Lewis, J. B., Riddle, M. C., Voors, A. A., Metra, M., et al. (2021) · New England Journal of Medicine · doi:10.1056/nejmoa2030183 · Cited by 1,868
Self-citationCardiovascular events with finerenone in kidney disease and type 2 diabetes
Pitt, B., Filippatos, G., Agarwal, R., Anker, S. D., Bakris, G. L., Rossing, P., Joseph, A., Kolkhof, P., Nowack, C., Schloemer, P., et al. (2021) · New England Journal of Medicine · doi:10.1056/nejmoa2110956 · Cited by 1,814
Agarwal, R., Filippatos, G., Pitt, B., Anker, S. D., Rossing, P., Joseph, A., Kolkhof, P., Nowack, C., Gebel, M., Ruilope, L. M., et al. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehab777 · Cited by 1,317
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Self-citationBaigent, C., Emberson, J., Haynes, R., Herrington, W. G., Judge, P., Landray, M. J., Mayne, K. J., Ng, S. Y. A., Preiss, D., Roddick, A. J., et al. (2022) · The Lancet · doi:10.1016/s0140-6736(22)02074-8 · Cited by 1,020
Self-citationVaduganathan, M., Docherty, K. F., Claggett, B. L., Jhund, P. S., de Boer, R. A., Hernandez, A. F., Inzucchi, S. E., Kosiborod, M. N., Lam, C. S. P., Martinez, F., et al. (2022) · The Lancet · doi:10.1016/s0140-6736(22)01429-5 · Cited by 996
Self-citationde Boer, I. H., Khunti, K., Sadusky, T., Tuttle, K. R., Neumiller, J. J., Rhee, C. M., Rosas, S. E., Rossing, P., & Bakris, G. (2022) · Diabetes Care · doi:10.2337/dci22-0027 · Cited by 919
Flagged first, then by citations
Research works printed but not linked: 35
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McEvoy, J. W., McCarthy, C. P., Bruno, R. M., Brouwers, S., Canavan, M. D., Ceconi, C., Christodorescu, R. M., Daskalopoulou, S. S., Ferro, C. J., Gerdts, E., et al. (2024) · European Heart Journal · doi:10.1093/eurheartj/ehae178 · Cited by 2,298
Self-citationSemaglutide in Patients with Obesity-Related Heart Failure and Type 2 Diabetes
Kosiborod, M. N., Petrie, M. C., Borlaug, B. A., Butler, J., Davies, M. J., Hovingh, G. K., Kitzman, D. W., Møller, D. V., Treppendahl, M. B., Verma, S., et al. (2024) · New England Journal of Medicine · doi:10.1056/nejmoa2313917 · Cited by 758
Self-citationNeuen, B. L., Heerspink, H. J. L., Vart, P., Claggett, B. L., Fletcher, R. A., Arnott, C., de Oliveira Costa, J., Falster, M. O., Pearson, S.-A., Mahaffey, K. W., et al. (2024) · Circulation · doi:10.1161/circulationaha.123.067584 · Cited by 358
Neuen, B. L., Fletcher, R. A., Heath, L., Perkovic, A., Vaduganathan, M., Badve, S. V., Tuttle, K. R., Pratley, R., Gerstein, H. C., Perkovic, V., et al. (2024) · Circulation · doi:10.1161/circulationaha.124.071689 · Cited by 168
Semaglutide and Tirzepatide in Patients With Heart Failure With Preserved Ejection Fraction
Krüger, N., Schneeweiss, S., Fuse, K., Matseyko, S., Sreedhara, S. K., Hahn, G., Schunkert, H., & Wang, S. V. (2025) · JAMA · doi:10.1001/jama.2025.14092 · Cited by 66
Ndumele, C. E., Rodriguez, F., Dixon, D. L., Khan, S. S., Mukherjee, D., Bajaj, M., Bangalore, S., Bozkurt, B., Breathett, K., Clarke, S. L., et al. (2026) · JACC · doi:10.1016/j.jacc.2026.03.056 · Cited by 90
Kani, R., Miyamoto, Y., Saito, T., Watanabe, A., Matsubara, K., Ejiri, K., Iwagami, M., Slipczuk, L., Hosseini, K., Fujisaki, T., et al. (2025) · International Journal of Cardiology · doi:10.1016/j.ijcard.2025.133079 · Cited by 10
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Metadata
- Authors
- McDonagh, T. A., Metra, M., Adamo, M., Gardner, R. S., Baumbach, A., Böhm, M., Burri, H., Butler, J., Čelutkienė, J., Chioncel, O., Cleland, J. G. F., Crespo-Leiro, M. G., Farmakis, D., Gilard, M., Heymans, S., Hoes, A. W., Jaarsma, T., Jankowska, E. A., Lainscak, M., Lam, C. S. P., Lyon, A. R., McMurray, J. J. V., Mebazaa, A., Mindham, R., Muneretto, C., Francesco Piepoli, M., Price, S., Rosano, G. M. C., Ruschitzka, F., Skibelund, A. K., ESC Scientific Document Group, de Boer, R. A., Schulze, P. C., Arbelo, E., Bartunek, J., Bauersachs, J., Borger, M. A., Buccheri, S., Cerbai, E., Donal, E., Edelmann, F., Färber, G., Heidecker, B., Ibanez, B., James, S., Køber, L., Koskinas, K. C., Masip, J., McEvoy, J. W., Mentz, R., Mihaylova, B., Møller, J. E., Mullens, W., Neubeck, L., Nielsen, J. C., Pasquet, A. A., Ponikowski, P., Prescott, E., Rakisheva, A., Rocca, B., Rossello, X., Sade, L. E., Schaubroeck, H., Tessitore, E., Tokmakova, M., van der Meer, P., Van Gelder, I. C., Van Heetvelde, M., Vrints, C., Wilhelm, M., Witkowski, A., Zeppenfeld, K., Shuka, N., Chettibi, M., Hayrapetyan, H., Pavo, N., Islamli, A., Pouleur, A.-C., Kusljugic, Z., Tokmakova, M., Milicic, D., Christodoulides, T., Malek, F., Køber, L., Koriem, M. A. G., Põder, P., Lassus, J., Roubille, F., Agladze, V., Frantz, S., Stavrati, A., Kosztin, A., Ingimarsdóttir, I. J., Campbell, P., Hasin, T., Oliva, F., Aidargaliyeva, N., Bajraktari, G., Mirrakhimov, E., Kamzola, G., El Neihoum, A. M., Zaliaduonyte, D., Moore, A., Vataman, E., Boskovic, A., Alami, M., Manintveld, O., Kostovska, E. S., Broch, K., Nessler, J., Franco, F., Popescu, B. A., Foscoli, M., Milosavljevic, A. S., Goncalvesova, E., Fras, Z., Gonzalez-Costello, J., Lindmark, K., Paul, M., Oudeh, A., Zakhama, L., Celik, A., Voronkov, L., Clark, A., Abdullaev, T., Prescott, E., James, S., Arbelo, E., Baigent, C., Borger, M. A., Buccheri, S., Ibanez, B., Køber, L., Koskinas, K. C., McEvoy, J. W., Mihaylova, B., Mindham, R., Neubeck, L., Nielsen, J. C., Pasquet, A. A., Rakisheva, A., Rocca, B., Rossello, X., Vaartjes, I., Vrints, C., Witkowski, A., & Zeppenfeld, K.
- Affiliations
- (Chairperson) ( )
- (Task Force Co-ordinator) ( )
- (United Kingdom)
- (Germany)
- (Switzerland)
- (United States of America)
- (Lithuania)
- (Romania)
- (Spain)
- (Greece)
- (France)
- (Netherlands)
- (Sweden)
- (Poland)
- (Slovenia)
- (Singapore)
- (Italy)
- (Denmark)
- ORCID
- McDonagh, Theresa A
- Metra, Marco
- Adamo, Marianna
- Gardner, Roy S
- Baumbach, Andreas
- Böhm, Michael
- Burri, Haran
- Butler, Javed
- Čelutkienė, Jelena
- Chioncel, Ovidiu
- Cleland, John G F
- Crespo-Leiro, Maria Generosa
- Farmakis, Dimitrios
- Gilard, Martine
- Heymans, Stephane
- Hoes, Arno W
- Jaarsma, Tiny
- Jankowska, Ewa A
- Lainscak, Mitja
- Lam, Carolyn S P
- Lyon, Alexander R
- McMurray, John J V
- Mebazaa, Alexandre
- Muneretto, Claudio
- Francesco Piepoli, Massimo
- Price, Susanna
- Ruschitzka, Frank
- Venue
- European Heart Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2023-08-25
- Volume
- 44
- Issue
- 37
- Pages
- 3627-3639
- ISSN
- 0195-668X
- 1522-9645
- Cited by
- 2,612
- References
- 16
- Language
- en
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