The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Long-term survival in patients undergoing cardiac resynchronization therapy: the importance of performing atrio-ventricular junction ablation in patients with permanent atrial fibrillation
Open accessAbstract
AIMS: To investigate the effects of cardiac resynchronization therapy (CRT) on survival in heart failure (HF) patients with permanent atrial fibrillation (AF) and the role of atrio-ventricular junction (AVJ) ablation in these patients. METHODS AND RESULTS: Data from 1285 consecutive patients implanted with CRT devices are presented: 1042 patients were in sinus rhythm (SR) and 243 (19%) in AF. Rate control in AF was achieved by either ablating the AVJ in 118 patients (AVJ-abl) or prescribing negative chronotropic drugs (AF-Drugs). Compared with SR, patients with AF were significantly older, more likely to be non-ischaemic, with higher ejection fraction, shorter QRS duration, and less often received ICD back-up. During a median follow-up of 34 months, 170/1042 patients in SR and 39/243 in AF died (mortality: 8.4 and 8.9 per 100 person-year, respectively). Adjusted hazard ratios were similar for all-cause and cardiac mortality [0.9 (0.57-1.42), P = 0.64 and 1.00 (0.60-1.66) P = 0.99, respectively]. Among AF patients, only 11/118 AVJ-abl patients died vs. 28/125 AF-Drugs patients (mortality: 4.3 and 15.2 per 100 person-year, respectively, P < 0.001). Adjusted hazard ratios of AVJ-abl vs. AF-Drugs was 0.26 [95% confidence interval (CI) 0.09-0.73, P = 0.010] for all-cause mortality, 0.31 (95% CI 0.10-0.99, P = 0.048) for cardiac mortality, and 0.15 (95% CI 0.03-0.70, P = 0.016) for HF mortality. CONCLUSION: Patients with HF and AF treated with CRT have similar mortality compared with patients in SR. In AF, AVJ ablation in addition to CRT significantly improves overall survival compared with CRT alone, primarily by reducing HF death.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Amiodarone or an Implantable Cardioverter–Defibrillator for Congestive Heart Failure
Bardy, G. H., Lee, K. L., Mark, D. B., Poole, J. E., Packer, D. L., Boineau, R., Domanski, M., Troutman, C., Anderson, J., Johnson, G., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa043399 · Cited by 6,552
Bristow, M. R., Saxon, L. A., Boehmer, J., Krueger, S., Kass, D. A., De Marco, T., Carson, P., DiCarlo, L., DeMets, D., White, B. G., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa032423 · Cited by 5,812
Cardiac Resynchronization in Chronic Heart Failure
Abraham, W. T., Fisher, W. G., Smith, A. L., Delurgio, D. B., Leon, A. R., Loh, E., Kocovic, D. Z., Packer, M., Clavell, A. L., Hayes, D. L., et al. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa013168 · Cited by 4,648
Wang, T. J., Larson, M. G., Levy, D., Vasan, R. S., Leip, E. P., Wolf, P. A., D’Agostino, R. B., Murabito, J. M., Kannel, W. B., & Benjamin, E. J. (2003) · Circulation · doi:10.1161/01.cir.0000072767.89944.6e · Cited by 1,970
GEELEN, P., BRUGADA, J., ANDRIES, E., & BRUGADA, P. (1997) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.1997.tb06179.x · Cited by 168
Cited by
Daubert, J.-C., Saxon, L., Adamson, P. B., Auricchio, A., Berger, R. D., Beshai, J. F., Breithard, O., Brignole, M., Cleland, J., DeLurgio, D. B., et al. (2012) · Heart Rhythm · doi:10.1016/j.hrthm.2012.07.025 · Cited by 467
Self-citationKamath, G. S., Cotiga, D., Koneru, J. N., Arshad, A., Pierce, W., Aziz, E. F., Mandava, A., Mittal, S., & Steinberg, J. S. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.12.022 · Cited by 171
Santini, M., Gasparini, M., Landolina, M., Lunati, M., Proclemer, A., Padeletti, L., Catanzariti, D., Molon, G., Botto, G. L., La Rocca, L., et al. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.08.624 · Cited by 121
Self-citationThe European CRT Survey: 1 year (9–15 months) follow-up results
Bogale, N., Priori, S., Cleland, J. G. F., Brugada, J., Linde, C., Auricchio, A., van Veldhuisen, D. J., Limbourg, T., Gitt, A., Gras, D., et al. (2012) · European Journal of Heart Failure · doi:10.1093/eurjhf/hfr158 · Cited by 98
Self-citationCzech Society of Cardiology Guidelines for the Diagnosis and Treatment of Chronic Heart Failure 2011
Špinar, J., Vítovec, J., Hradec, J., Málek, I., Meluzín, J., Špinarová, L., Hošková, L., Hegarová, M., Ludka, O., & Táborský, M. (2012) · Cor et Vasa · doi:10.1016/j.crvasa.2012.03.002 · Cited by 10
Metadata
- Authors
- Gasparini, M., Auricchio, A., Metra, M., Regoli, F., Fantoni, C., Lamp, B., Curnis, A., Vogt, J., Klersy, C., & for the Multicentre Longitudinal Observational Study (MILOS) Group
- Venue
- European Heart Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2008-06-13
- Volume
- 29
- Issue
- 13
- Pages
- 1644-1652
- ISSN
- 0195-668X (ISSN-L)
- 1522-9645
- OpenAlex
- W2098429289
- Cited by
- 264
- References
- 5
- FWCI
- 21.56
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Long-term survival in patients undergoing cardiac resynchronization therapy: the importance of performing atrio-ventricular junction ablation in patients with permanent atrial fibrillation. https://app.cochat.ai/papers/10.1093/eurheartj/ehn133
- The paper
- Gasparini, M., Auricchio, A., Metra, M., Regoli, F., Fantoni, C., Lamp, B., Curnis, A., Vogt, J., Klersy, C., & for the Multicentre Longitudinal Observational Study (MILOS) Group. (2008). Long-term survival in patients undergoing cardiac resynchronization therapy: the importance of performing atrio-ventricular junction ablation in patients with permanent atrial fibrillation. European Heart Journal. https://doi.org/10.1093/eurheartj/ehn133
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
