The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Three-year follow-up and event rates in the international REduction of Atherothrombosis for Continued Health Registry
Open accessAbstract
AIMS: To determine 3-year event rates in outpatients with vascular disease enrolled in the REduction of Atherothrombosis for Continued Health (REACH) Registry. METHODS AND RESULTS: REACH enrolled 67 888 outpatients with atherothrombosis [established coronary artery disease (CAD), cerebrovascular disease, or peripheral arterial disease (PAD)], or with at least three atherothrombotic risk factors, from 44 countries. Among the 55 499 patients at baseline with symptomatic disease, 39 675 were eligible for 3-year follow-up, and 32 247 had data available (81% retention rate). Among the symptomatic patients at 3 years, 92% were taking an antithrombotic agent, 91% an antihypertensive, and 76% were on lipid-lowering therapy. For myocardial infarction (MI)/stroke/vascular death, 1- and 3-year event rates for all patients were 4.2 and 11.0%, respectively. Event rates (MI/stroke/vascular death) were significantly higher for patients with symptomatic disease vs. those with risk factors only at 1 year (4.7 vs. 2.3%, P < 0.001) and at 3 years (12.0 vs. 6.0%, P < 0.001). One and 3-year rates of MI/stroke/vascular death/rehospitalization were 14.4 and 28.4%, respectively, for patients with symptomatic disease. Rehospitalization for a vascular event other than MI/stroke/vascular death was common at 3 years (19.0% overall; 33.6% for PAD; 23.0% for CAD). For patients with symptomatic vascular disease in one vascular bed vs. multiple vascular beds, 3-year event rates for MI/stroke/vascular death/rehospitalization were 25.5 vs. 40.5% (P < 0.001). CONCLUSION: Despite contemporary therapy, outpatients with symptomatic atherothrombotic vascular disease experience high rates of recurrent vascular events and rehospitalizations.
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Yusuf, S., Hawken, S., Ôunpuu, S., Dans, T., Avezum, A., Lanas, F., McQueen, M., Budaj, A., Pais, P., Varigos, J., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)17018-9 · Cited by 12,026
The American Journal of Managed Care
(2020) · The American Journal of Managed Care · doi:10.37765/ajmc · Cited by 3,237
Yusuf, S., Reddy, S., Ôunpuu, S., & Anand, S. (2001) · Circulation · doi:10.1161/hc4601.099487 · Cited by 2,972
Bulletin of the World Health Organization
Frick, K. D., Lynch, M. C., West, S. K., Muñoz, B., & Mkocha, H. A. (2003) · Bulletin of the World Health Organization · Cited by 2,656
Bhatt, D. L. (2006) · JAMA · doi:10.1001/jama.295.2.180 · Cited by 1,627
Self-citationYusuf, S., Reddy, S., Ôunpuu, S., & Anand, S. (2001) · Circulation · doi:10.1161/hc4701.099488 · Cited by 1,141
de Araújo Gonçalves, P., Ferreira, J., Aguiar, C., & Seabra-Gomes, R. (2005) · European Heart Journal · doi:10.1093/eurheartj/ehi187 · Cited by 524
Ohman, E. M., Bhatt, D. L., Steg, P. G., Goto, S., Hirsch, A. T., Liau, C.-S., Mas, J.-L., Richard, A.-J., Röther, J., & Wilson, P. W. F. (2006) · American Heart Journal · doi:10.1016/j.ahj.2005.11.004 · Cited by 306
Self-citationDistribution of Major Health Risks: Findings from the Global Burden of Disease Study
Rodgers, A., Ezzati, M., Vander Hoorn, S., Lopez, A. D., Lin, R.-B., Murray, C. J. L., & Group Comparative Risk Assessment Collaborating (2004) · PLoS Medicine · doi:10.1371/journal.pmed.0010027 · Cited by 280
Reducing the Global Burden of Cardiovascular Disease: The Role of Risk Factors
Levenson, J. W., Skerrett, P. J., & Gaziano, J. M. (2002) · Preventive Cardiology · doi:10.1111/j.1520-037x.2002.00564.x · Cited by 233
Cited by
Cosentino, F., Grant, P. J., Aboyans, V., Bailey, C. J., Ceriello, A., Delgado, V., Federici, M., Filippatos, G., Grobbee, D. E., Hansen, T. B., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehz486 · Cited by 4,763
ESC Guidelines on the diagnosis and treatment of peripheral artery diseases
Endorsed by: the European Stroke Organisation (ESO), Authors/Task Force Members, Tendera, M., Aboyans, V., Bartelink, M.-L., Baumgartner, I., Clément, D., Collet, J.-P., Cremonesi, A., De Carlo, M., et al. (2011) · European Heart Journal · doi:10.1093/eurheartj/ehr211 · Cited by 1,506
Self-citation2024 ESC Guidelines for the management of peripheral arterial and aortic diseases
Mazzolai, L., Teixido-Tura, G., Lanzi, S., Boc, V., Bossone, E., Brodmann, M., Bura-Rivière, A., De Backer, J., Deglise, S., Della Corte, A., et al. (2024) · European Heart Journal · doi:10.1093/eurheartj/ehae179 · Cited by 993
Bhatt, D. L., Eagle, K. A., Ohman, E. M., Hirsch, A. T., Goto, S., Mahoney, E. M., Wilson, P. W. F., Alberts, M. J., D’Agostino, R., Liau, C.-S., et al. (2010) · JAMA · doi:10.1001/jama.2010.1322 · Cited by 753
Self-citationKumbhani, D. J., Steg, P. G., Cannon, C. P., Eagle, K. A., Smith, S. C., Goto, S., Ohman, E. M., Elbez, Y., Sritara, P., Baumgartner, I., et al. (2014) · European Heart Journal · doi:10.1093/eurheartj/ehu080 · Cited by 318
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Metadata
- Authors
- Alberts, M. J., Bhatt, D. L., Mas, J.-L., Ohman, E. M., Hirsch, A. T., Rother, J., Salette, G., Goto, S., Smith, S. C., Liau, C.-S., Wilson, P. W. F., Steg, P. G., & for the REduction of Atherothrombosis for Continued Health (REACH) Registry Investigators
- Venue
- European Heart Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-08-31
- Volume
- 30
- Issue
- 19
- Pages
- 2318-2326
- ISSN
- 0195-668X (ISSN-L)
- 1522-9645
- OpenAlex
- W2135989027
- Cited by
- 339
- References
- 20
- FWCI
- 11.27
- Type
- journal article
- Language
- en
- Open access
- green
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- Alberts, M. J., Bhatt, D. L., Mas, J.-L., Ohman, E. M., Hirsch, A. T., Rother, J., Salette, G., Goto, S., Smith, S. C., Liau, C.-S., Wilson, P. W. F., Steg, P. G., & for the REduction of Atherothrombosis for Continued Health (REACH) Registry Investigators. (2009). Three-year follow-up and event rates in the international REduction of Atherothrombosis for Continued Health Registry. European Heart Journal. https://doi.org/10.1093/eurheartj/ehp355
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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