The DOI matches its Crossref record; 147 of the 147 references it cites were found in a registry or an index.
Biomechanical factors in atherosclerosis: mechanisms and clinical implications
Open accessAbstract
Blood vessels are exposed to multiple mechanical forces that are exerted on the vessel wall (radial, circumferential and longitudinal forces) or on the endothelial surface (shear stress). The stresses and strains experienced by arteries influence the initiation of atherosclerotic lesions, which develop at regions of arteries that are exposed to complex blood flow. In addition, plaque progression and eventually plaque rupture is influenced by a complex interaction between biological and mechanical factors-mechanical forces regulate the cellular and molecular composition of plaques and, conversely, the composition of plaques determines their ability to withstand mechanical load. A deeper understanding of these interactions is essential for designing new therapeutic strategies to prevent lesion development and promote plaque stabilization. Moreover, integrating clinical imaging techniques with finite element modelling techniques allows for detailed examination of local morphological and biomechanical characteristics of atherosclerotic lesions that may be of help in prediction of future events. In this ESC Position Paper on biomechanical factors in atherosclerosis, we summarize the current 'state of the art' on the interface between mechanical forces and atherosclerotic plaque biology and identify potential clinical applications and key questions for future research.
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Cites
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Self-citationHemodynamic shear stress and its role in atherosclerosis
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Cited by
Borén, J., Chapman, M. J., Krauss, R. M., Packard, C. J., Bentzon, J. F., Binder, C. J., Daemen, M. J., Demer, L. L., Hegele, R. A., Nicholls, S. J., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehz962 · Cited by 1,601
Self-citationRoles of vascular oxidative stress and nitric oxide in the pathogenesis of atherosclerosis
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Borén, J., & Williams, K. J. (2016) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000330 · Cited by 524
Endothelial–mesenchymal transition in atherosclerosis
Souilhol, C., Harmsen, M. C., Evans, P. C., & Krenning, G. (2018) · Cardiovascular Research · doi:10.1093/cvr/cvx253 · Cited by 401
Self-citationRole of Vascular Smooth Muscle Cell Plasticity and Interactions in Vessel Wall Inflammation
Sorokin, V., Vickneson, K., Kofidis, T., Woo, C. C., Lin, X. Y., Foo, R., & Shanahan, C. M. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.599415 · Cited by 292
Metadata
- Authors
- Kwak, B. R., Bäck, M., Bochaton-Piallat, M.-L., Caligiuri, G., Daemen, M. J. A. P., Davies, P. F., Hoefer, I. E., Holvoet, P., Jo, H., Krams, R., Lehoux, S., Monaco, C., Steffens, S., Virmani, R., Weber, C., Wentzel, J. J., & Evans, P. C.
- Venue
- European Heart Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2014-09-17
- Volume
- 35
- Issue
- 43
- Pages
- 3013-3020
- ISSN
- 0195-668X (ISSN-L)
- 1522-9645
- OpenAlex
- W2096357860
- Cited by
- 502
- References
- 147
- FWCI
- 15.23
- Type
- journal article
- Language
- en
- Open access
- green
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- Kwak, B. R., Bäck, M., Bochaton-Piallat, M.-L., Caligiuri, G., Daemen, M. J. A. P., Davies, P. F., Hoefer, I. E., Holvoet, P., Jo, H., Krams, R., Lehoux, S., Monaco, C., Steffens, S., Virmani, R., Weber, C., Wentzel, J. J., & Evans, P. C. (2014). Biomechanical factors in atherosclerosis: mechanisms and clinical implications. European Heart Journal. https://doi.org/10.1093/eurheartj/ehu353
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
