Gender-related differences in outcomes and resource utilization in patients undergoing radiofrequency ablation of supraventricular tachycardia: results from Patients' Perspective on Radiofrequency Catheter Ablation of AVRT and AVNRT Study
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AIMS: The aim of this study was to describe gender-related differences in clinical presentation, radiofrequency ablation (RFA) outcomes, and healthcare resource utilization in a group of patients with atrioventricular nodal reciprocating tachycardia (AVNRT) and atrioventricular reciprocating tachycardia (AVRT). METHODS AND RESULTS: This was a single-centre, prospective, cohort study which enroled 82 patients undergoing RFA of AVNRT or AVRT. At baseline, all patients received a clinical assessment and completed questionnaires concerning: socioeconomic status, disease-specific symptoms (Patient Perception of Arrhythmia Questionnaire; PPAQ), health-related quality of life (HRQoL) (EQ-5D-3L), and healthcare resource utilization. Two months after RFA, the clinical assessment was repeated and subjects completed PPAQ and EQ-5D-3L. Follow-up was completed by 64 patients, 41 (64%) women. At baseline, there were no significant differences in baseline characteristics, except AVNRT prevalence, and HRQoL by gender but women reported higher severity of symptoms on PPAQ than men (2.8 vs. 2.4 points, P < 0.001). At 2 months after RFA, women still reported higher severity of symptoms (1.8 vs. 0 points; P = 0.02) on PPAQ and more heart skipping than men (54 vs. 13%; P = 0.0014); differences in EQ-5D-3L index and EQ-VAS were insignificant. There was no significant difference in healthcare resource utilization during the year preceding RFA, but antiarrhythmic drugs were significantly more often prescribed to women pre-procedure (30 vs. 8%; P = 0.022). CONCLUSION: There is a small but significant gender-related difference in outcome of RFA in patients with AVNRT or AVRT measured with a disease-specific instrument. No significant difference in HRQoL or access to healthcare resources between women and men was found.
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Almost all studies examining quality of life with validated questionnaires have been conducted in patients undergoing catheter ablation for supraventricular tachycardia, often without a comparison group.
“Almost all of the studies examining QoL, measured with validated questionnaires, have been conducted in patients undergoing catheter ablation for SVT, 245,246,254 - 256,258,424,425 although often without a comparison group.”
From European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE) (2017) · cites this paper as [245]
Several studies have investigated patient-reported quality of life and may offer some insight into patient preferences where particular therapies result in improvements in quality of life.
“Several studies have investigated patient-reported QoL, 2,245,246,254 -256,258,424,425 and these may offer some insight into patient preferences for treatment where particular therapies result in improvements in QoL.”
From European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE) (2017) · cites this paper as [245]
Every study has demonstrated an improvement in self-reported quality of life following ablation.
“Every study has demonstrated an improvement in self-reported QoL following ablation.2,245,246,254 -256,258,424,425”
From European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE) (2017) · cites this paper as [245]
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- Authors
- Farkowski, M. M., Pytkowski, M., Maciag, A., Golicki, D., Wood, K. A., Kowalik, I., Kuteszko, R., & Szwed, H.
- Affiliations
- Institute of Cardiology (PL)
- Medical University of Warsaw (PL)
- Duke University (US)
- Corresponding author
- Farkowski, M. M.
- Venue
- Europace
- Publisher
- Oxford University Press (OUP)
- Published
- 2014-06-11
- Volume
- 16
- Issue
- 12
- Pages
- 1821-1827
- ISSN
- 1099-5129 (ISSN-L)
- 1532-2092
- OpenAlex
- W2165839919
- Cited by
- 45
- References
- 30
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 4 · 2022: 5 · 2021: 4 · 2020: 4 · 2019: 5 · 2018: 7 · 2017: 4 · 2016: 6 · 2015: 3 · 2013: 1
- FWCI
- 2.97
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- EP Europace (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Keywords
- supraventricular tachycardia, atrioventricular reciprocating tachycardia, radiofrequency catheter ablation, gender differences, healthcare resource utilization, health-related quality of life, symptom severity, antiarrhythmic drug use
- MeSH terms
- Adult, Female, Humans, Male, Poland, Risk Factors, Socioeconomic Factors, Tachycardia, Supraventricular, Utilization Review, Health Care Rationing, Prevalence, Treatment Outcome, Catheter Ablation, Sex Distribution, Resource Allocation
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