The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
A genetic mapping system in Caenorhabditis elegans based on polymorphic sequence-tagged sites.
Open accessAbstract
We devised an efficient genetic mapping system in the nematode Caenorhabditis elegans which is based upon the differences in number and location of the transposable element Tc1 between the Bristol and Bergerac strains. Using the nearly completed physical map of the C. elegans genome, we selected 40 widely distributed sites which contain a Tc1 element in the Bergerac strain, but not in the Bristol strain. For each site a polymerase chain reaction assay was designed that can distinguish between the Bergerac Tc1-containing site and the Bristol "empty" site. By combining appropriate assays in a single reaction, one can score multiple sites within single worms. This permits a mutation to be rapidly mapped, first to a linkage group and then to a chromosomal subregion, through analysis of only a small number of progeny from a single interstrain cross.
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Cites
Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase
Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. J., Higuchi, R., Horn, G. T., Mullis, K. B., & Erlich, H. A. (1988) · Science · doi:10.1126/science.2448875 · Cited by 17,719
Cited by
Legouis, R., Gansmuller, A., Sookhareea, S., Bosher, J. M., Baillie, D. L., & Labouesse, M. (2000) · Nature Cell Biology · doi:10.1038/35017046 · Cited by 189
Van Auken, K., Weaver, D. C., Edgar, L. G., & Wood, W. B. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.9.4499 · Cited by 89
Miley, G. R., Fantz, D., Glossip, D., Lu, X., Saito, R. M., Palmer, R. E., Inoue, T., van den Heuvel, S., Sternberg, P. W., & Kornfeld, K. (2004) · Genetics · doi:10.1534/genetics.104.029017 · Cited by 28
Metadata
- Authors
- Williams, B. D., Schrank, B., Huynh, C., Shownkeen, R., & Waterston, R. H.
- Venue
- Genetics
- Publisher
- Oxford University Press (OUP)
- Published
- 1992-07-01
- Volume
- 131
- Issue
- 3
- Pages
- 609-624
- ISSN
- 0016-6731 (ISSN-L)
- 1943-2631
- OpenAlex
- W1847602617
- Cited by
- 496
- References
- 1
- FWCI
- 14.56
- Type
- journal article
- Language
- en
- Open access
- bronze
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