The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Seven genes of the Enhancer of split complex of Drosophila melanogaster encode helix-loop-helix proteins.
Open accessAbstract
Enhancer of split [E(spl)] is one of the neurogenic loci of Drosophila and, as such, is required for normal segregation of neural and epidermal cell progenitors. Genetic observations indicate that the E(spl) locus is in fact a gene complex comprising a cluster of related genes and that other genes of the region are also required for normal early neurogenesis. Three of the genes of the complex were known to encode helix-loop-helix (HLH) proteins and to be transcribed in nearly identical patterns. Here, we show that four other genes in the vicinity also encode HLH proteins and, during neuroblast segregation, three of them are expressed in the same pattern. We show by germ-line transformation that these three genes are also necessary to allow epidermal development of the neuroectodermal cells.
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Cites
The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins
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The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation
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Artavanis-Tsakonas, S., Matsuno, K., & Fortini, M. E. (1995) · Science · doi:10.1126/science.7716513 · Cited by 1,303
MicroRNA functions in animal development and human disease
Alvarez-Garcia, I., & Miska, E. A. (2005) · Development · doi:10.1242/dev.02073 · Cited by 1,104
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Metadata
- Authors
- Knust, E., Schrons, H., Grawe, F., & Campos-Ortega, J. A.
- Venue
- Genetics
- Publisher
- Oxford University Press (OUP)
- Published
- 1992-10-01
- Volume
- 132
- Issue
- 2
- Pages
- 505-518
- ISSN
- 0016-6731 (ISSN-L)
- 1943-2631
- OpenAlex
- W1844615320
- Cited by
- 218
- References
- 3
- FWCI
- 5.98
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Knust, E., Schrons, H., Grawe, F., & Campos-Ortega, J. A. (1992). Seven genes of the Enhancer of split complex of Drosophila melanogaster encode helix-loop-helix proteins. Genetics. https://doi.org/10.1093/genetics/132.2.505
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