The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Interval mapping of multiple quantitative trait loci.
Open accessAbstract
The interval mapping method is widely used for the mapping of quantitative trait loci (QTLs) in segregating generations derived from crosses between inbred lines. The efficiency of detecting and the accuracy of mapping multiple QTLs by using genetic markers are much increased by employing multiple QTL models instead of the single QTL models (and no QTL models) used in interval mapping. However, the computational work involved with multiple QTL models is considerable when the number of QTLs is large. In this paper it is proposed to combine multiple linear regression methods with conventional interval mapping. This is achieved by fitting one QTL at a time in a given interval and simultaneously using (part of) the markers as cofactors to eliminate the effects of additional QTLs. It is shown that the proposed method combines the easy computation of the single QTL interval mapping method with much of the efficiency and accuracy of multiple QTL models.
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Citations
Cites
Haley, C. S., & Knott, S. A. (1992) · Heredity · doi:10.1038/hdy.1992.131 · Cited by 1,991
Martínez, O., & Curnow, R. N. (1992) · Theoretical and Applied Genetics · doi:10.1007/bf00222330 · Cited by 355
Cited by
Precision mapping of quantitative trait loci.
Zeng, Z. B. (1994) · Genetics · doi:10.1093/genetics/136.4.1457 · Cited by 3,182
High resolution of quantitative traits into multiple loci via interval mapping.
Jansen, R. C., & Stam, P. (1994) · Genetics · doi:10.1093/genetics/136.4.1447 · Cited by 1,046
Self-citationThe genetics of plant metabolism
Keurentjes, J. J. B., Fu, J., de Vos, C. H. R., Lommen, A., Hall, R. D., Bino, R. J., van der Plas, L. H. W., Jansen, R. C., Vreugdenhil, D., & Koornneef, M. (2006) · Nature Genetics · doi:10.1038/ng1815 · Cited by 499
Self-citationTheoretical Basis of the Beavis Effect
Xu, S. (2003) · Genetics · doi:10.1093/genetics/165.4.2259 · Cited by 464
QTL analysis in plants; where are we now?
Kearsey, M. J., & Farquhar, A. G. L. (1998) · Heredity · doi:10.1046/j.1365-2540.1998.00500.x · Cited by 492
Metadata
- Authors
- Jansen, R. C.
- Venue
- Genetics
- Publisher
- Oxford University Press (OUP)
- Published
- 1993-09-01
- Volume
- 135
- Issue
- 1
- Pages
- 205-211
- ISSN
- 0016-6731 (ISSN-L)
- 1943-2631
- OpenAlex
- W2109085886
- Cited by
- 850
- References
- 2
- FWCI
- 9.10
- Type
- journal article
- Language
- en
- Open access
- bronze
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