The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Estimation of Pairwise Relatedness With Molecular Markers
Abstract
Applications of quantitative genetics and conservation genetics often require measures of pairwise relationships between individuals, which, in the absence of known pedigree structure, can be estimated only by use of molecular markers. Here we introduce methods for the joint estimation of the two-gene and four-gene coefficients of relationship from data on codominant molecular markers in randomly mating populations. In a comparison with other published estimators of pairwise relatedness, we find these new “regression” estimators to be computationally simpler and to yield similar or lower sampling variances, particularly when many loci are used or when loci are hypervariable. Two examples are given in which the new estimators are applied to natural populations, one that reveals isolation-by-distance in an annual plant and the other that suggests a genetic basis for a coat color polymorphism in bears.
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Cites
The genetical evolution of social behaviour. I
Hamilton, W. D. (1964) · Journal of Theoretical Biology · doi:10.1016/0022-5193(64)90038-4 · Cited by 15,725
Cited by
Robust relationship inference in genome-wide association studies
Manichaikul, A., Mychaleckyj, J. C., Rich, S. S., Daly, K., Sale, M., & Chen, W.-M. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btq559 · Cited by 3,541
Variance component model to account for sample structure in genome-wide association studies
Kang, H. M., Sul, J. H., Service, S. K., Zaitlen, N. A., Kong, S.-Y., Freimer, N. B., Sabatti, C., & Eskin, E. (2010) · Nature Genetics · doi:10.1038/ng.548 · Cited by 2,817
New insights from fine‐scale spatial genetic structure analyses in plant populations
Vekemans, X., & Hardy, O. J. (2004) · Molecular Ecology · doi:10.1046/j.1365-294x.2004.02076.x · Cited by 1,313
Little, J., Higgins, J. P. T., Ioannidis, J. P. A., Moher, D., Gagnon, F., von Elm, E., Khoury, M. J., Cohen, B., Davey-Smith, G., Grimshaw, J., et al. (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000022 · Cited by 811
Burgueño, J., de los Campos, G., Weigel, K., & Crossa, J. (2012) · Crop Science · doi:10.2135/cropsci2011.06.0299 · Cited by 601
Metadata
- Authors
- Lynch, M., & Ritland, K.
- Venue
- Genetics
- Publisher
- Oxford University Press (OUP)
- Published
- 1999-08-01
- Volume
- 152
- Issue
- 4
- Pages
- 1753-1766
- ISSN
- 0016-6731 (ISSN-L)
- 1943-2631
- OpenAlex
- W1855982476
- Cited by
- 1,186
- References
- 1
- FWCI
- 8.11
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
