Quantitative Trait Loci Controlling Light and Hormone Response in Two Accessions of Arabidopsis thaliana
Abstract
We have mapped quantitative trait loci (QTL) responsible for natural variation in light and hormone response between the Cape Verde Islands (Cvi) and Landsberg erecta (Ler) accessions of Arabidopsis thaliana using recombinant inbred lines (RILs). Hypocotyl length was measured in four light environments: white, blue, red, and far-red light and in the dark. In addition, white light plus gibberellin (GA) and dark plus the brassinosteroid biosynthesis inhibitor brassinazole (BRZ) were used to detect hormone effects. Twelve QTL were identified that map to loci not previously known to affect light response, as well as loci where candidate genes have been identified from known mutations. Some QTL act in all environments while others show genotype-by-environment interaction. A global threshold was established to identify a significant epistatic interaction between two loci that have few main effects of their own. LIGHT1, a major QTL, has been confirmed in a near isogenic line (NIL) and maps to a new locus with effects in all light environments. The erecta mutation can explain the effect of the HYP2 QTL in the blue, BRZ, and dark environments, but not in far-red. LIGHT2, also confirmed in an NIL, has effects in white and red light and shows interaction with GA. The phenotype and map position of LIGHT2 suggest the photoreceptor PHYB as a candidate gene. Natural variation in light and hormone response thus defines both new genes and known genes that control light response in wild accessions.
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Modified quantitative trait loci strategies can be applied across species to identify orthologs that regulate similar traits in other species.
“there is potential to use modified quantitative trait loci (QTL) strategies, and apply these across species to identify orthologs that regulate similar traits in other species [113]”
From Biofuels from algae: Challenges and potential (2010) · cites this paper as [113]
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- Authors
- Borevitz, J. O., Maloof, J. N., Lutes, J., Dabi, T., Redfern, J. L., Trainer, G. T., Werner, J. D., Asami, T., Berry, C. C., Weigel, D., & Chory, J.
- Affiliations
- Salk Institute for Biological Studies (US)
- RIKEN (JP)
- University of California System (US)
- Corresponding author
- Chory, Joanne
- Venue
- Genetics
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-02-01
- Volume
- 160
- Issue
- 2
- Pages
- 683-696
- ISSN
- 0016-6731 (ISSN-L)
- 1943-2631
- OpenAlex
- W1958937417
- Cited by
- 128
- References
- 62
- Citations by year
- 2026: 1 · 2024: 2 · 2023: 4 · 2022: 3 · 2021: 4 · 2020: 3 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 3 · 2015: 1 · 2014: 3 · 2013: 3 · 2012: 7
- FWCI
- 18.53
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
- Locations
- Genetics (publishedVersion)
- PubMed (publishedVersion)
- Max Planck Institute for Plasma Physics (submittedVersion)
- Funders
- National Institutes of Health (5p60ar040770-09)
- National Institute of General Medical Sciences (GM08666, R01GM052413, GM 52413, T32GM008666)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (AR 40770)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Light effects on plants
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Mapping and Diversity in Plants and Animals
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Genetic and Mutation Studies
- Keywords
- quantitative trait loci, light response, endocrine response, Arabidopsis thaliana, Landsberg erecta, hypocotyl length, gene-environment interaction, epistasis, gibberellin, brassinazole, brassinosteroid biosynthesis, blue light, far-red light, natural variation, recombinant inbred lines, near-isogenic lines
- MeSH terms
- Light, Photoreceptor Cells, Phytochrome, Plant Growth Regulators, Transcription Factors, Genetic Variation, Arabidopsis, Quantitative Trait, Heritable, Arabidopsis Proteins, Phytochrome B
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