The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
THE EFFECT OF A SELECTED LOCUS ON LINKED NEUTRAL LOCI
Abstract
The effects produced on linked neutral loci as a selected locus evolves towards its equilibrium value are considered. Significant effects on the neutral loci arise if the recombination fraction between the neutral and selected loci is smaller than the order of magnitude of the selective differences at the selected locus. The effect on gene frequencies at the neutral loci, that is, the hitchhiking effect, is determined, as well as the linkage disequilibrium generated by this hitchhiking effect. One of the more important findings is that significant disequilibrium can be generated between two neutral loci by the evolution of a linked selected locus. Consideration is given to the problem of determining how the effect of selection operating in natural populations can be detected, the question of the establishment of inversions in populations, and also to the nonequilibrium properties of populations.
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Cites
Linkage disequilibrium in finite populations
Hill, W. G., & Robertson, A. (1968) · Theoretical and Applied Genetics · doi:10.1007/bf01245622 · Cited by 2,035
C. Genetics of Man Enzyme polymorphisms in man
Harris, H. (1966) · Proceedings of the Royal Society of London. Series B. Biological Sciences · doi:10.1098/rspb.1966.0032 · Cited by 611
LINKAGE DISEQUILIBRIUM AT STEADY STATE DETERMINED BY RANDOM GENETIC DRIFT AND RECURRENT MUTATION
Ohta, T., & Kimura, M. (1969) · Genetics · doi:10.1093/genetics/63.1.229 · Cited by 181
Linkage and selection: Two locus symmetric viability model
Karlin, S., & Feldman, M. W. (1970) · Theoretical Population Biology · doi:10.1016/0040-5809(70)90041-9 · Cited by 174
Jennings, H. S. (1917) · Genetics · doi:10.1093/genetics/2.2.97 · Cited by 110
Cited by
Hitchhiking Under Positive Darwinian Selection
Fay, J. C., & Wu, C.-I. (2000) · Genetics · doi:10.1093/genetics/155.3.1405 · Cited by 1,819
Associations Among Protein Heterozygosity, Growth Rate, and Developmental Homeostasis
Mitton, J. B., & Grant, M. C. (1984) · Annual Review of Ecology and Systematics · doi:10.1146/annurev.ecolsys.15.1.479 · Cited by 721
RECOMBINATION AND THE MULTILOCUS STRUCTURE OF FUNGAL POPULATIONS
Milgroom, M. G. (1996) · Annual Review of Phytopathology · doi:10.1146/annurev.phyto.34.1.457 · Cited by 549
Mutation-selection balance and the evolutionary advantage of sex and recombination
Charlesworth, B. (1990) · Genetical Research · doi:10.1017/s0016672300025532 · Cited by 398
The effect of background selection against deleterious mutations on weakly selected, linked variants
Charlesworth, B. (1994) · Genetical Research · doi:10.1017/s0016672300032365 · Cited by 366
Metadata
- Authors
- Thomson, G.
- Venue
- Genetics
- Publisher
- Oxford University Press (OUP)
- Published
- 1977-04-01
- Volume
- 85
- Issue
- 4
- Pages
- 753-788
- ISSN
- 0016-6731 (ISSN-L)
- 1943-2631
- OpenAlex
- W1814098872
- Cited by
- 205
- References
- 5
- FWCI
- 7.14
- Type
- journal article
- Language
- en
- Open access
- closed
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- Thomson, G. (1977). THE EFFECT OF A SELECTED LOCUS ON LINKED NEUTRAL LOCI. Genetics. https://doi.org/10.1093/genetics/85.4.753
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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