Resveratrol Alleviates Inflammation and ER Stress Through SIRT1/NRF2 to Delay Ovarian Aging in a Short-Lived Fish

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

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Resveratrol protects against age-associated infertility in mice

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Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury

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Resveratrol Alleviates Rheumatoid Arthritis via Reducing ROS and Inflammation, Inhibiting MAPK Signaling Pathways, and Suppressing Angiogenesis

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Excessive oxidative stress in cumulus granulosa cells induced cell senescence contributes to endometriosis-associated infertility

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The Absence of Nrf2 Enhances NF-B-Dependent Inflammation following Scratch Injury in Mouse Primary Cultured Astrocytes

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SIRT1 exerts protective effects against paraquat-induced injury in mouse type II alveolar epithelial cells by deacetylating NRF2 in vitro

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The protective effect of resveratrol on vascular aging by modulation of the renin–angiotensin system

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Melatonin prevents senescence of canine adipose-derived mesenchymal stem cells through activating NRF2 and inhibiting ER stress

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Resveratrol reduces senescence-associated secretory phenotype by SIRT1/NF-κB pathway in gut of the annual fish Nothobranchius guentheri

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Resveratrol alleviates chemotherapy-induced oogonial stem cell apoptosis and ovarian aging in mice

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Resveratrol protects mice from paraquat-induced lung injury: The important role of SIRT1 and NRF2 antioxidant pathways

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Effects of plant polyphenols on ovarian follicular reserve in aging ratsThis paper is one of a selection of papers published in this special issue entitled “Second International Symposium on Recent Advances in Basic, Clinical, and Social Medicine” and has undergone the Journal's usual peer review process.

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Effects of resveratrol on longevity, cognitive ability and aging-related histological markers in the annual fish Nothobranchius guentheri

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Sirt1/Nrf2 pathway is involved in oocyte aging by regulating Cyclin B1

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Protective effect of resveratrol against oxidative damage to ovarian reserve in female Sprague–Dawley rats

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Metformin prevents murine ovarian aging

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Age-Related Markers Assayed at Different Developmental Stages of the Annual Fish Nothobranchius rachovii

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Proliferating Cell Nuclear Antigen—A Marker for Ovarian Follicle Counts

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The underlying mechanism of proinflammatory NF-κB activation by the mTORC2/Akt/IKKα pathway during skin aging

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Melatonin attenuates palmitic acid-induced mouse granulosa cells apoptosis via endoplasmic reticulum stress

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Effects of deletion of the transcription factor Nrf2 and benzo [a]pyrene treatment on ovarian follicles and ovarian surface epithelial cells in mice

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Early Life Exposure to Undernutrition Induces ER Stress, Apoptosis, and Reduced Vascularization in Ovaries of Adult Rat Offspring1

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Oogenesis, vitellogenin-mediated ovarian degeneration and immune response in the annual fish Nothobranchius guentheri

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Resveratrol Protects Cardiac Tissue in Experimental Malignant Hypertension Due to Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Properties

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Folic acid attenuates remodeling and dysfunction in the aging heart through the ER stress pathway

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Dietary Intake of β-Glucans Can Prolong Lifespan and Exert an Antioxidant Action on Aged Fish Nothobranchius guentheri

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Resveratrol and organic selenium-rich fermented milk reduces d -galactose-induced cognitive dysfunction in mice

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Time-dependent effects of late-onset dietary intake of salidroside on lifespan and age-related biomarkers of the annual fish Nothobranchius guentheri

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Dietary resveratrol increases mid-life fecundity of female Nothobranchius guentheri

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Intravenous human endothelial progenitor cell administration into aged mice enhances embryo development and oocyte quality by reducing inflammation, endoplasmic reticulum stress and apoptosis

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Resveratrol inhibits age-dependent spontaneous tumorigenesis by SIRT1-mediated post-translational modulations in the annual fish Nothobranchius guentheri

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Control of Murine Primordial Follicle Growth Activation by IκB/NFκB Signaling

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Metformin Protects Against Inflammation, Oxidative Stress to Delay Poly I:C-Induced Aging-Like Phenomena in the Gut of an Annual Fish

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The influence of the gut microbiome on ovarian aging

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Resveratrol: Molecular Mechanisms, Health Benefits, and Potential Adverse Effects

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Dietary Polyphenols as Anti-Aging Agents: Targeting the Hallmarks of Aging

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Role of the Nrf2 Signaling Pathway in Ovarian Aging: Potential Mechanism and Protective Strategies

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Resveratrol improves emamectin benzoate-induced pyroptosis and inflammation of Ctenopharyngodon idellus hepatic cells by alleviating oxidative stress/endoplasmic reticulum stress

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Smart glucose-responsive hydrogel with ROS scavenging and homeostasis regulating properties for diabetic bone regeneration

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SIRT1 Alleviates Oxidative Stress‐Induced Mitochondrial Dysfunction and Mitochondria‐Associated Membrane Dysregulation in Stress Urinary Incontinence

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Molecular Mechanism of Resveratrol and Its Therapeutic Potential on Female Infertility

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Pterostilbene, a Resveratrol Derivative, Improves Ovary Function by Upregulating Antioxidant Defenses in the Aging Chickens via Increased SIRT1/Nrf2 Expression

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Impact of Resveratrol Supplementation on Human Sirtuin 1: A Grading of Recommendations Assessment, Development and Evaluation–Assessed Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials

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Resveratrol in Dermatological Therapy: A Critical Review of Mechanisms, Delivery Innovations, and Clinical Frontiers

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Effects of resveratrol on biochemical and structural outcomes in osteoarthritis: A systematic review and meta-analysis of preclinical studies

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Grape‐Derived Exosome‐Like Nanovesicles Effectively Ameliorate Skin Photoaging by Protecting Epithelial Cells

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Therapeutic potential of natural products in stress granules: Underlying molecular mechanisms and future perspectives

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Immp2l gene knockout induces granulosa cell senescence by activation of cGAS-STING pathway via TFAM-mediated mtDNA leakage

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Effects and mechanisms of aflatoxin B1 on oocytes and embryo development

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Resveratrol‑mediated activation of SIRT1 inhibits the PERK‑eIF2α‑ATF4 pathway and mitigates bupivacaine‑induced neurotoxicity in PC12 cells

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Resveratrol derivative SH-707 inhibits NLRP3 inflammasome activation via a sirtuin 1-dependent pathway

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Role and mechanisms of plant polyphenols in ovarian aging

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Resveratrol and Its Analogues: Anti-ageing Effects and Underlying Mechanisms

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Dietary resveratrol alleviates liver and intestinal injury in ducks under cage rearing system

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Celastrol modulates IRS1 expression to alleviate ovarian aging and to enhance follicular development

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Melatonin promotes parthenogenetic development of vitrified-warmed mouse MII oocytes, potentially by reducing oxidative stress through SIRT1

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Zebrafish TDP43 positively regulates p65-mediated apoptotic pathway.

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Resveratrol alleviates lipid deposition, endoplasmic reticulum stress, inflammation and apoptosis in the livers of large yellow croaker (Larimichthys crocea) fed with a soybean oil-based diet

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Li, F., Huang, Y.-J., Liu, Z., Geng, Y.-L., Hu, R.-N., Song, Y.-F., Xu, L.-J., & Zhang, M.-M. (2026) · Biomedicines · doi:10.3390/biomedicines14030714 · Cited by 3 · see citing works

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Natural Small Molecules Targeting Oxidative Stress and Redox Homeostasis in Aging: Mechanisms and Therapeutic Potential

Li, Y., Wu, H., Zhang, Z., Wang, M., Zhao, Y. Q., & Sun, H. (2026) · Antioxidants · doi:10.3390/antiox15050621 · Cited by 4 · see citing works

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Ozone water enema activates SIRT1-Nrf2/HO-1 pathway to ameliorate gut dysbiosis in mice receiving COVID-19 patient-derived faecal microbiota

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Glycosylation Matters: Network Pharmacology-Based and Molecular Docking Analysis of Resveratrol Glycosylated Derivatives on Parkinson’s Disease

Schimith, L. E., Martis, E., Télétchéa, S., Muccillo-Baisch, A. L., André‐Miral, C., & Hort, M. A. (2026) · ACS Omega · doi:10.1021/acsomega.5c08887 · Cited by 2 · see citing works

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Zhang, J., Fu, Q., Wang, Y., Mu, Y., Ren, H., Xue, L., & Liu, J. (2025) · Aquaculture Reports · doi:10.1016/j.aqrep.2025.102983 · Cited by 2 · see citing works

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Resveratrol exerts stage- and sex-specific anti-aging and multigenerational effects via epigenetic and metabolic pathways in Drosophila

Wu, Q., Ouyang, B., Ma, W., Zhao, Y., Liang, J., Yuan, Y., Cao, H., Simal‐Gándara, J., Nie, S., & Xiao, J. (2026) · Phytomedicine · doi:10.1016/j.phymed.2026.158531 · Cited by 1 · see citing works

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Matsumoto, H., Vidal, S. V., Tomaz, D. C. M. F., & Pacheco, P. M. D. C. F. (2024) · doi:10.22533/at.ed.24924080312 · Cited by 1 · see citing works

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Lima, D. D. M., Aleixo, J. L., Dias, V. S. D. M., & da Silva, R. N. (2024) · doi:10.22533/at.ed.2492408038

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Viração, P. D. D., Verçosa, C. J., Ulisses, V. R. D. A., Rocha, J. E., Macêdo, G. F., de Araújo, W. P., dos Santos, M. A. F., Almeida‐Bezerra, J. W., Filho, A. M., Costa, A. R., et al. (2024) · doi:10.22533/at.ed.2492408035

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Palmeira, A. C. D. C., Barros, J. N. D., de Souza, E. D. O., Leal, W. R. C., Sousa, W. A., Sousa, E. D. L. S., Palmeira, M. D. S., de Sousa, L. R., Teixeira, E. B., & Pinho, J. D. (2024) · doi:10.22533/at.ed.2492408037

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Santuzzi, C. H., Mengal, V., Liberato, F. M. G., Tiradentes, R. V., Zanon, P. H. A., & Gouvêa, S. A. (2024) · doi:10.22533/at.ed.2492408036

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Godoi, R. C., Costa, M. C. D. A., Dinelli, I. C., Corrêa, M. E. G. G., Júnior, P. R. H., Prieto, A. E. C., Hernandes, N. N. F., & Júnior, H. S. D. F. (2024) · doi:10.22533/at.ed.2492408031

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Costa, M. C. D. A., Rodovalho, C. C., Dinelli, I. C., Corrêa, M. E. G. G., Godoi, R. C., Júnior, P. R. H., Prieto, A. E. C., Hernandes, N. N. F., & Sousa, N. B. E. (2024) · doi:10.22533/at.ed.2492408032

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Báo, A. C. P., Candaten, Â. E., Bertoldi, K., Lauer, R. D., Timponi, S. C. J., da Rosa, G. F., Faturi, J. S., & de Souza, A. D. Z. (2024) · doi:10.22533/at.ed.2492408034

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de Mendonça, E. L. S. S., Rocha, T. D. S., da Silva, M. O., Lima, M. P. S., de Oliveira, R. L. B., Xavier, A. F. D. A., de Oliveira, A. C. M., Xavier, J. A., & Goulart, M. O. F. (2024) · doi:10.22533/at.ed.24924080321

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Gomes, M. A. F., Pereira, L. C., Pereira, A. S., Silva, A. K. L., & Tôsto, S. G. (2024) · doi:10.22533/at.ed.24924080323

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Arruda, M. J. A. L. L. A., Bento, P. M., & Baldin, N. (2024) · doi:10.22533/at.ed.24924080311

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Melo, L. B. D., Lima, A. P., Leão, L. D. C., & Barini, B. F. (2024) · doi:10.22533/at.ed.24924080317

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Machado, C. D., Machado, R. A. D. M., de Sousa, A. S., Soares, G. D. R., Bender, J. R., Grattagliano, P. F. T., Dapper, A. A., Stenger, T. D. A., Harkovtzeff, F. B. P., & Draghetti, E. L. (2024) · doi:10.22533/at.ed.24924080320

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Corrêa, M. E. G. G., Costa, M. C. D. A., Dinelli, I. C., Godoi, R. C., Júnior, P. R. H., Prieto, A. E. C., Hernandes, N. N. F., & Sousa, N. B. E. (2024) · doi:10.22533/at.ed.2492408033

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Pairazamán, A. T. E., Herrera, E. C., PINTO, J. D. C., Fustamante, F. L. B., Chávez, J. R., Justiniano, C. G. B., Cardenas, P. B. E., Alva, P. M. G., & Alvarado, E. O. (2024) · F1000Research · doi:10.12688/f1000research.143351.1

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Gong, S., Zhang, C., Xue, C., Yang, X., & Xue, C. (2024) · Archives of Insect Biochemistry and Physiology · doi:10.1002/arch.70007

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Silica Nanoparticles Induced Epithelial–Mesenchymal Transition in BEAS-2B Cells via ER Stress and SIRT1/HSF1/HSPs Signaling Pathway

Pang, J., Xiao, L., Xiong, Z., Zhang, K., Yang, M. G., Wang, J., Li, Y., & Li, Y. (2025) · Journal of Xenobiotics · doi:10.3390/jox15050137

Research Progress on Treating Polycystic Ovary Syndrome Based on Endoplasmic Reticulum Stress

郭, 琴. (2025) · Advances in Clinical Medicine · doi:10.12677/acm.2025.15113159

Exploring NAD+ Biology in Fish: From Cellular Metabolism to Ecological Adaptations and Aquaculture Strategies

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Expression profiles of the sirtuin genes family during ovarian development and hormonal regulation in Pampus argenteus

Wang, C., Zhang, H., Wang, Y., Zhang, K., Wang, X., Wang, X., & Guo, C. (2026) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2026.114874

Multifacet Roles of Cellular Senescence in Cancer: Mechanisms and Therapeutic Implications

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β‐1,3‐Glucan mediates innate immunity and anti‐aging effects in aged male Nothobranchius guentheri and protects against Aeromonas hydrophila infection

Song, L., Qiao, H., Lan, J., An, K., & Huang, Y. (2026) · Journal of Fish Biology · doi:10.1111/jfb.70546

The PERK paradox in aging: how ER stress shapes senescence and neurodegeneration

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Mitochondria-Targeted Natural-Derived Compounds in Cellular Senescence: Mechanisms, Therapeutic Potential, and Future Directions

Namkaew, J., Kongpracha, P., & Jaroonwitchawan, T. (2026) · Biology · doi:10.3390/biology15151328

Resveratrol Attenuates Oxidative Stress, Mitochondrial Dysfunction, and Dysregulation of Protein Turnover Induced by Excessive Glucose in Olive Flounder ( Paralichthys olivaceus ) Muscle Cells

Cheng, S., Zhang, J., Fu, Q., Xue, L., Mu, Y., Ren, H., & Liu, J. (2026) · Aquaculture Research · doi:10.1155/are/8361909

The potential role of NLRP3 inflammasome in integrating redox, metabolic, and inflammatory signals during follicular development: a hypothesis-driven redox-metabolic integrator framework

Zhang, Z., Wang, D., Lin, Q., Guo, P., & Wang, Z. (2026) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2026.1914362

Decoding the immune regulation of ovarian aging: mechanisms and therapeutic strategies

Wang, C., Li, N., Chen, Z., Qin, Y., & Jiao, X. (2026) · Human Reproduction Update · doi:10.1093/humupd/dmag030

Dose- and Time-dependent Histopathological and Immunotoxic Effects of DEHP on the Spleen of Sparidentex hasta: Implications for Fish Health and Veterinary Toxicology

Lamoochi, R., Doustshenas, B., Shirali, S., Gasemi, A., & Sakhaei, N. (2026) · Archives of Razi Institute · doi:10.66224/ari.81.3.3830

Resveratrol improves ovarian function in aged rat by inhibiting oxidative stress and activating the Sirt1

Wu, H., Xue, J., Di, H., Lv, C., Hao, Y., & Nie, Z. (2022) · General Physiology and Biophysics · doi:10.4149/gpb_2021040 · Cited by 20 · see citing works

Resveratrol reduces senescence-associated secretory phenotype by SIRT1/NF-κB pathway in gut of the annual fish Nothobranchius guentheri

Liu, S., Zheng, Z., Ji, S., Liu, T., Hou, Y., Li, S., & Li, G. (2018) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2018.06.027 · Cited by 96 · see citing works

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Lee, Y., Drake, A. C., Thomas, N. O., Ferguson, L. G., Chappell, P. E., & Shay, K. P. (2017) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cbpc.2017.10.006 · Cited by 18 · see citing works

Resveratrol and SIRT1: Antiaging Cornerstones for Oocytes?

Grzeczka, A., & Kordowitzki, P. (2022) · Nutrients · doi:10.3390/nu14235101 · Cited by 30 · see citing works

Resveratrol Attenuates Oxidative Stress and Extends Life Span in the Annual Fish Nothobranchius guentheri

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