The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Siglecs—the major subfamily of I-type lectins
Abstract
Animal glycan-recognizing proteins can be broadly classified into two groups-lectins (which typically contain an evolutionarily conserved carbohydrate-recognition domain [CRD]) and sulfated glycosaminoglycan (SGAG)-binding proteins (which appear to have evolved by convergent evolution). Proteins other than antibodies and T-cell receptors that mediate glycan recognition via immunoglobulin (Ig)-like domains are called "I-type lectins." The major homologous subfamily of I-type lectins with sialic acid (Sia)-binding properties and characteristic amino-terminal structural features are called the "Siglecs" (Sia-recognizing Ig-superfamily lectins). The Siglecs can be divided into two groups: an evolutionarily conserved subgroup (Siglecs-1, -2, and -4) and a CD33/Siglec-3-related subgroup (Siglecs-3 and -5-13 in primates), which appear to be rapidly evolving. This article provides an overview of historical and current information about the Siglecs.
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Cites
Order Out of Chaos: Assembly of Ligand Binding Sites in Heparan Sulfate
Esko, J. D., & Selleck, S. B. (2002) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.71.110601.135458 · Cited by 1,495
Evolutionary Rate in the Protein Interaction Network
Fraser, H. B., Hirsh, A. E., Steinmetz, L. M., Scharfe, C., & Feldman, M. W. (2002) · Science · doi:10.1126/science.1068696 · Cited by 869
TREMs in the immune system and beyond
Colonna, M. (2003) · Nature Reviews Immunology · doi:10.1038/nri1106 · Cited by 701
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Cited by
Glycan-based interactions involving vertebrate sialic-acid-recognizing proteins
Varki, A. (2007) · Nature · doi:10.1038/nature05816 · Cited by 853
Self-citationSchnaar, R. L., Gerardy-Schahn, R., & Hildebrandt, H. (2014) · Physiological Reviews · doi:10.1152/physrev.00033.2013 · Cited by 745
Advances in the Biology and Chemistry of Sialic Acids
Chen, X., & Varki, A. (2010) · ACS Chemical Biology · doi:10.1021/cb900266r · Cited by 543
Self-citationCarlin, A. F., Uchiyama, S., Chang, Y.-C., Lewis, A. L., Nizet, V., & Varki, A. (2009) · Blood · doi:10.1182/blood-2008-11-187302 · Cited by 401
Self-citationMyelin‐associated glycoprotein (MAG): past, present and beyond
Quarles, R. H. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.04319.x · Cited by 326
Metadata
- Authors
- Varki, A., & Angata, T.
- Venue
- Glycobiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-07-13
- Volume
- 16
- Issue
- 1
- Pages
- 1R-27R
- ISSN
- 0959-6658 (ISSN-L)
- 1460-2423
- OpenAlex
- W2154872900
- Cited by
- 518
- References
- 6
- FWCI
- 11.64
- Type
- journal article
- Language
- en
- Open access
- closed
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