The DOI matches its Crossref record; 118 of the 118 references it cites were found in a registry or an index.
Myelin‐associated glycoprotein (MAG): past, present and beyond
Abstract
The myelin‐associated glycoprotein (MAG) is a type I transmembrane glycoprotein localized in periaxonal Schwann cell and oligodendroglial membranes of myelin sheaths where it functions in glia–axon interactions. It contains five immunoglobulin (Ig)‐like domains and is in the sialic acid‐binding subgroup of the Ig superfamily. It appears to function both as a ligand for an axonal receptor that is needed for the maintenance of myelinated axons and as a receptor for an axonal signal that promotes the differentiation, maintenance and survival of oligodendrocytes. Its function in the maintenance of myelinated axons may be related to its role as one of the white matter inhibitors of neurite outgrowth acting through a receptor complex involving the Nogo receptor and/or gangliosides containing 2,3‐linked sialic acid. MAG is expressed as two developmentally regulated isoforms with different cytoplasmic domains that may activate different signal transduction pathways in myelin‐forming cells. MAG contains a carbohydrate epitope shared with other glycoconjugates that is a target antigen in autoimmune peripheral neuropathy associated with IgM gammopathy and has been implicated in a dying back oligodendrogliopathy in multiple sclerosis.
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Citations
Cites
Glial inhibition of CNS axon regeneration
Yiu, G., & He, Z. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1956 · Cited by 1,495
Basic Neurochemistry???Molecular, Cellular, and Medical Aspects
Long, D. M. (2006) · Neurosurgery Quarterly · doi:10.1097/01.wnq.0000203279.82150.41 · Cited by 1,284
Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion
Barnett, M. H., & Prineas, J. W. (2004) · Annals of Neurology · doi:10.1002/ana.20016 · Cited by 1,185
p75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp
Wang, K. C., Kim, J. A., Sivasankaran, R., Segal, R., & He, Z. (2002) · Nature · doi:10.1038/nature01176 · Cited by 819
Peripheral neuropathies and anti-glycolipid antibodies
Willison, H. J. (2002) · Brain · doi:10.1093/brain/awf272 · Cited by 710
Myelin-Associated Glycoprotein Interacts with the Nogo66 Receptor to Inhibit Neurite Outgrowth
Domeniconi, M., Cao, Z., Spencer, T., Sivasankaran, R., Wang, K. C., Nikulina, E., Kimura, N., Cai, H., Deng, K., Gao, Y., et al. (2002) · Neuron · doi:10.1016/s0896-6273(02)00770-5 · Cited by 593
Myelin-Associated Glycoprotein as a Functional Ligand for the Nogo-66 Receptor
Liu, B. P., Fournier, A., GrandPré, T., & Strittmatter, S. M. (2002) · Science · doi:10.1126/science.1073031 · Cited by 577
Bjartmar, C., Wujek, J. R., & Trapp, B. D. (2003) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(02)00069-2 · Cited by 573
Siglecs—the major subfamily of I-type lectins
Varki, A., & Angata, T. (2006) · Glycobiology · doi:10.1093/glycob/cwj008 · Cited by 518
Myelin-Associated Glycoprotein Is a Myelin Signal that Modulates the Caliber of Myelinated Axons
Yin, X., Crawford, T. O., Griffin, J. W., Tu, P.-H., Lee, V. M.-Y., Li, C., Roder, J., & Trapp, B. D. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-06-01953.1998 · Cited by 496
Cited by
Myelination and support of axonal integrity by glia
Nave, K.-A. (2010) · Nature · doi:10.1038/nature09614 · Cited by 1,062
Schnaar, R. L., Gerardy-Schahn, R., & Hildebrandt, H. (2014) · Physiological Reviews · doi:10.1152/physrev.00033.2013 · Cited by 745
Prolonged myelination in human neocortical evolution
Miller, D. J., Duka, T., Stimpson, C. D., Schapiro, S. J., Baze, W. B., McArthur, M. J., Fobbs, A. J., Sousa, A. M. M., Šestan, N., Wildman, D. E., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1117943109 · Cited by 699
Glycomimetics versus Multivalent Glycoconjugates for the Design of High Affinity Lectin Ligands
Cecioni, S., Imberty, A., & Vidal, S. (2015) · Chemical Reviews · doi:10.1021/cr500303t · Cited by 544
Myelin Proteomics: Molecular Anatomy of an Insulating Sheath
Jahn, O., Tenzer, S., & Werner, H. B. (2009) · Molecular Neurobiology · doi:10.1007/s12035-009-8071-2 · Cited by 329
Metadata
- Authors
- Quarles, R. H.
- Venue
- Journal of Neurochemistry
- Publisher
- Wiley
- Published
- 2006-11-09
- Volume
- 100
- Issue
- 6
- Pages
- 1431-1448
- ISSN
- 0022-3042 (ISSN-L)
- 1471-4159
- OpenAlex
- W2064253207
- Cited by
- 326
- References
- 118
- FWCI
- 7.50
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
