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Structural stability and chromosome-specific telomere length is governed by cis-acting determinants in humans
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“Human chromosome ends usually have detectable telomere repeats between 0.5 and 15 kilobases (kb), depending on factors such as tissue type, donor age, and cell replication history.”
From Cell Immortality: In Vitro Effective Techniques to Achieve and Investigate Its Applications and Challenges (2024) · cites this paper as [51]
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Cites
A DNA damage checkpoint response in telomere-initiated senescence
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“Ultimately this results in the loss of telomeric function and the triggering of a p53dependent DNA-damage checkpoint termed replicative senescence (2).”
BackgroundSenescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors
Campisi, J. (2005) · Cell · doi:10.1016/j.cell.2005.02.003 · Cited by 2,379
Association between telomere length in blood and mortality in people aged 60 years or older
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Extensive allelic variation and ultrashort telomeres in senescent human cells
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Self-citationShort telomeres on human chromosome 17p
Martens, U. M., Zijlmans, J. M. J. M., Poon, S. S. S., Dragowska, W., Yui, J., Chavez, E. A., Ward, R. K., & Lansdorp, P. M. (1998) · Nature Genetics · doi:10.1038/ng0198-018 · Cited by 393
Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts
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Self-citationAccumulation of Short Telomeres in Human Fibroblasts Prior to Replicative Senescence
Martens, U. M., Chavez, E. A., Poon, S. S. S., Schmoor, C., & Lansdorp, P. M. (2000) · Experimental Cell Research · doi:10.1006/excr.2000.4823 · Cited by 263 · cited 1×
“Furthermore, Q-FISH analysis suggested that the inactive X-chromosome exhibits elevated rates of telomere erosion and has unusual dynamics during replicative senescence (19,20).”
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Cited by
Aubert, G., & Lansdorp, P. M. (2008) · Physiological Reviews · doi:10.1152/physrev.00026.2007 · Cited by 1,188
Aubert, G., Hills, M., & Lansdorp, P. M. (2012) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2011.04.003 · Cited by 342
Telomere Length: A Review of Methods for Measurement
Montpetit, A. J., Alhareeri, A. A., Montpetit, M., Starkweather, A. R., Elmore, L. W., Filler, K., Mohanraj, L., Burton, C. W., Menzies, V. S., Lyon, D. E., et al. (2014) · Nursing Research · doi:10.1097/nnr.0000000000000037 · Cited by 293
The nature of telomere fusion and a definition of the critical telomere length in human cells
Capper, R., Britt-Compton, B., Tankimanova, M., Rowson, J., Letsolo, B., Man, S., Haughton, M., & Baird, D. M. (2007) · Genes & Development · doi:10.1101/gad.439107 · Cited by 294
Self-citationLin, T. T., Letsolo, B. T., Jones, R. E., Rowson, J., Pratt, G., Hewamana, S., Fegan, C., Pepper, C., & Baird, D. M. (2010) · Blood · doi:10.1182/blood-2010-02-272104 · Cited by 178
Self-citation
Metadata
- Authors
- Britt-Compton, B., Rowson, J., Locke, M., Mackenzie, I., Kipling, D., & Baird, D. M.
- Venue
- Human Molecular Genetics
- Publisher
- Oxford University Press (OUP)
- Published
- 2006-01-18
- Volume
- 15
- Issue
- 5
- Pages
- 725-733
- ISSN
- 1460-2083
- 0964-6906
- Cited by
- 114
- References
- 12
- Language
- en
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