A novel Usher protein network at the periciliary reloading point between molecular transport machineries in vertebrate photoreceptor cells

Visual cells and the concept of renewal.

Young, R. W. (1976) · PubMed · Cited by 482 · see citing works

Rhodopsin’s Carboxy-Terminal Cytoplasmic Tail Acts as a Membrane Receptor for Cytoplasmic Dynein by Binding to the Dynein Light Chain Tctex-1

Tai, A. W., Chuang, J.-Z., Bode, C., Uwe Wolfrum, B., & Sung, C.-H. (1999) · Cell · doi:10.1016/s0092-8674(00)80800-4 · Cited by 478 · see citing works

Molecular basis of human Usher syndrome: Deciphering the meshes of the Usher protein network provides insights into the pathomechanisms of the Usher disease

Reiners, J., Nagel‐Wolfrum, K., Jürgens, K., Märker, T., & Uwe Wolfrum, B. (2006) · Experimental Eye Research · doi:10.1016/j.exer.2005.11.010 · Cited by 305 · see citing works

U SHER S YNDROME : From Genetics to Pathogenesis

Petit, C. (2001) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.2.1.271 · Cited by 280 · see citing works

Usherin is required for maintenance of retinal photoreceptors and normal development of cochlear hair cells

Liu, X., Bulgakov, O. V., Darrow, K. N., Pawlyk, B. S., Adamian, M., Liberman, M. C., & Li, T. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610950104 · Cited by 274 · see citing works

Usher syndrome: molecular links of pathogenesis, proteins and pathways

Kremer, H., van Wijk, E., Märker, T., Uwe Wolfrum, B., & Roepman, R. (2006) · Human Molecular Genetics · doi:10.1093/hmg/ddl205 · Cited by 255 · see citing works

Interactions in the network of Usher syndrome type 1 proteins

Adato, A., Michel, V., Kikkawa, Y., et al. (2004) · Human Molecular Genetics · doi:10.1093/hmg/ddi031 · Cited by 248 · see citing works

A novel gene for Usher syndrome type 2: mutations in the long isoform of whirlin are associated with retinitis pigmentosa and sensorineural hearing loss

Ebermann, I., Scholl, H. P. N., Issa, P. C., Bećirović, E., Lamprecht, J., Jurklies, B., Millán, J. M., Aller, E., Mitter, D., & Bolz, H. J. (2006) · Human Genetics · doi:10.1007/s00439-006-0304-0 · Cited by 237 · see citing works

Vezatin, a novel transmembrane protein, bridges myosin VIIA to the cadherin–catenins complex

Küssel‐Andermann, P., El‐Amraoui, A., Safieddine, S., Nouaille, S., Perfettini, I., Lecuit, M., Cossart, P., Uwe Wolfrum, B., & Petit, C. (2000) · The EMBO Journal · doi:10.1093/emboj/19.22.6020 · Cited by 229 · see citing works

Ciliary and flagellar membranes

(1990) · Choice Reviews Online · doi:10.5860/choice.28-0284 · Cited by 226 · see citing works

The Very Large G-Protein-Coupled Receptor VLGR1: A Component of the Ankle Link Complex Required for the Normal Development of Auditory Hair Bundles

McGee, J., Goodyear, R. J., McMillan, D. R., Stauffer, E. A., Holt, J. R., Locke, K. G., Birch, D. G., Legan, P. K., White, P. C., Walsh, E. J., et al. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.0693-06.2006 · Cited by 221 · see citing works

Molecular Characterization of the Ankle-Link Complex in Cochlear Hair Cells and Its Role in the Hair Bundle Functioning

Michalski, N., Michel, V., Bahloul, A., et al. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0342-07.2007 · Cited by 220 · see citing works

Rhodopsin C terminus, the site of mutations causing retinal disease, regulates trafficking by binding to ADP-ribosylation factor 4 (ARF4)

Deretic, D., Williams, A. H., Ransom, N. L., Morel, V., Hargrave, P. A., & Arendt, A. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0500095102 · Cited by 197 · see citing works

Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly

Delprat, B., Michel, V., Goodyear, R. J., et al. (2004) · Human Molecular Genetics · doi:10.1093/hmg/ddi036 · Cited by 193 · see citing works

The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1

van Wijk, E., van der Zwaag, B., Peters, T. A., Zimmermann, U., Brinke, H. T., Kersten, F. F. J., Märker, T., Aller, E., Hoefsloot, L. H., Cremers, C. W. R. J., et al. (2006) · Human Molecular Genetics · doi:10.1093/hmg/ddi490 · Cited by 193 · see citing works

Usherin, the defective protein in Usher syndrome type IIA, is likely to be a component of interstereocilia ankle links in the inner ear sensory cells

Adato, A., Lefevre, G. M., Delprat, B., Michel, V., Michalski, N., Chardenoux, S., Weil, D., El-Amraoui, A., & Petit, C. (2005) · Human Molecular Genetics · doi:10.1093/hmg/ddi416 · Cited by 185 · see citing works

Vesicular transport of newly synthesized opsin from the Golgi apparatus toward the rod outer segment. Ultrastructural immunocytochemical and autoradiographic evidence in Xenopus retinas.

Papermaster, D. S., Schneider, B., & Besharse, J. C. (1985) · PubMed · Cited by 181 · see citing works

Scaffold protein harmonin (USH1C) provides molecular links between Usher syndrome type 1 and type 2

Reiners, J., van Wijk, E., Märker, T., Zimmermann, U., Jürgens, K., Brinke, H. T., Overlack, N., Roepman, R., Knipper, M., Kremer, H., et al. (2005) · Human Molecular Genetics · doi:10.1093/hmg/ddi417 · Cited by 174 · see citing works

The molecular genetics of Usher syndrome

Ahmed, Z., Riazuddin, S. A., Riazuddin, S., & Wilcox, E. R. (2003) · Clinical Genetics · doi:10.1034/j.1399-0004.2003.00109.x · Cited by 163 · see citing works

Very Large G Protein-coupled Receptor-1, the Largest Known Cell Surface Protein, Is Highly Expressed in the Developing Central Nervous System

McMillan, D. R., Kayes, K. M., Richardson, J. A., & White, P. C. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m108929200 · Cited by 148 · see citing works

Fine structure of a periciliary ridge complex of frog retinal rod cells revealed by ultrahigh resolution scanning electron microscopy

Peters, K. (1983) · The Journal of Cell Biology · doi:10.1083/jcb.96.1.265 · Cited by 132 · see citing works

Protein Networks and Complexes in Photoreceptor Cilia

Roepman, R., & Wolfrum, U. (2007) · Springer eBooks · doi:10.1007/978-1-4020-5943-8_10 · Cited by 122 · see citing works

The Photoreceptor Connecting Cilium A Model for the Transition Zone

Besharse, J. C., & Horst, C. J. (1990) · Springer eBooks · doi:10.1007/978-1-4613-0515-6_15 · Cited by 118 · see citing works

The Ankle-Link Antigen: an Epitope Sensitive to Calcium Chelation Associated with the Hair-Cell Surface and the Calycal Processes of Photoreceptors

Goodyear, R. J., & Richardson, G. P. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-10-03761.1999 · Cited by 99 · see citing works

Rhodopsin Trafficking and its Role in Retinal Dystrophies

Sung, C.-H., & Tai, A. W. (1999) · International review of cytology · doi:10.1016/s0074-7696(08)62706-0 · Cited by 97 · see citing works

Loss of the transmembrane and cytoplasmic domains of the very large G-protein-coupled receptor-1 (VLGR1 or Mass1) causes audiogenic seizures in mice

McMillan, D. R., & White, P. C. (2004) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2004.02.005 · Cited by 89 · see citing works

Membrane assembly in retinal photoreceptors I. Freeze-fracture analysis of cytoplasmic vesicles in relationship to disc assembly.

Besharse, J. C., & Pfenninger, K. H. (1980) · The Journal of Cell Biology · doi:10.1083/jcb.87.2.451 · Cited by 88 · see citing works

A role for rhodopsin in a signal transduction cascade that regulates membrane trafficking and photoreceptor polarity

Deretic, D. (2006) · Vision Research · doi:10.1016/j.visres.2006.07.028 · Cited by 86 · see citing works

Recurring views on the structure and function of the cytoskeleton: A 300-Year Epic

Frixione, E. (2000) · Cell Motility and the Cytoskeleton · doi:10.1002/1097-0169(200006)46:2 · Cited by 85 · see citing works

A Novel Antigen Sensitive to Calcium Chelation That is Associated with the Tip Links and Kinocilial Links of Sensory Hair Bundles

Goodyear, R. J., & Richardson, G. P. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-12-04878.2003 · Cited by 83 · see citing works

Biosynthesis and vectorial transport of opsin on vesicles in retinal rod photoreceptors.

Papermaster, D. S., Schneider, B., Defoe, D. M., & Besharse, J. C. (1986) · Journal of Histochemistry & Cytochemistry · doi:10.1177/34.1.2934469 · Cited by 83 · see citing works

Differential Distribution of Harmonin Isoforms and Their Possible Role in Usher-1 Protein Complexes in Mammalian Photoreceptor Cells

Reiners, J., Reidel, B., El-Amraoui, A., Boëda, B., Huber, I., Petit, C., & Uwe Wolfrum, B. (2003) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.03-0483 · Cited by 82 · see citing works

Actin-based motor properties of native myosin VIIa

Udovichenko, I. P., Gibbs, D., & Williams, D. S. (2002) · Journal of Cell Science · doi:10.1242/jcs.115.2.445 · Cited by 82 · see citing works

Differential Expression and Interaction with the Visual G-protein Transducin of Centrin Isoforms in Mammalian Photoreceptor Cells

Gießl, A., Pulvermüller, A., Trojan, P., Park, J. H., Choe, H., Ernst, O. P., Hofmann, K. P., & Uwe Wolfrum, B. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m406770200 · Cited by 78 · see citing works

Phosphoinositides, Ezrin/Moesin, and rac1 Regulate Fusion of Rhodopsin Transport Carriers in Retinal Photoreceptors

Deretic, D., Traverso, V., Parkins, N., Jackson, F. R., Turco, E., & Ransom, N. L. (2003) · Molecular Biology of the Cell · doi:10.1091/mbc.e03-04-0203 · Cited by 68 · see citing works

Presynaptic terminal differentiation: transport and assembly

Zhen, M., & Jin, Y. (2004) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2004.05.013 · Cited by 67 · see citing works

Expression of Centrin Isoforms in the Mammalian Retina

Wolfrum, U., & Salisbury, J. L. (1998) · Experimental Cell Research · doi:10.1006/excr.1998.4038 · Cited by 67 · see citing works

Centrin in the photoreceptor cells of mammalian retinae

Wolfrum, U. (1995) · Cell Motility and the Cytoskeleton · doi:10.1002/cm.970320107 · Cited by 63 · see citing works

The birth and death of photoreceptors: the Friedenwald Lecture.

Papermaster, D. S. (2002) · PubMed · Cited by 56 · see citing works

SANS (USH1G) expression in developing and mature mammalian retina

Overlack, N., Maerker, T., Latz, M., et al. (2007) · Vision Research · doi:10.1016/j.visres.2007.08.021 · Cited by 39 · see citing works

[45] Isolation of retinal proteins that interact with retinitis pigmentosa gtpase regulator by interaction trap screen in yeast

Roepman, R., Schick, D., & Ferreira, P. A. (2000) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(00)16757-6 · Cited by 30 · see citing works

Photoreceptor vitality in organotypic cultures of mature vertebrate retinas validated by light-dependent molecular movements

Reidel, B., Orisme, W., Goldmann, T., et al. (2006) · Vision Research · doi:10.1016/j.visres.2006.07.019 · Cited by 25 · see citing works

Tropomyosin is co-localized with the actin filaments of the scolopale in insect sensilla

Wolfrum, U. (1991) · Cell and Tissue Research · doi:10.1007/bf00318134 · Cited by 21 · see citing works

Shortening of the calycal process actin cytoskeleton is correlated with myoid elongation in teleost rods

Pagh-Roehl, K., Wang, E., & Burnside, B. (1992) · Experimental Eye Research · doi:10.1016/0014-4835(92)90178-u · Cited by 20 · see citing works

The Role of Cadherins in Ca2+-Mediated Cell Adhesion and Inherited Photoreceptor Degeneration

Bolz, H. J., Reiners, J., Uwe Wolfrum, B., & Gal, A. (2002) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-0121-3_24 · Cited by 17 · see citing works

[38] Immunocytochemistry of retinal membrane protein biosynthesis at the electron microscopic level by the albumin embedding technique

Schneider, B., & Papermaster, D. S. (1983) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(83)96042-1 · Cited by 16 · see citing works

Heterogeneity in the Usher syndrome

van Aarem, A. (1996) · Cited by 12 · see citing works

Congenital Adrenal Hyperplasia—Current Insights in Pathophysiology, Diagnostics, and Management

Claahsen - van der Grinten, H. L., Speiser, P. W., Ahmed, S. F., Arlt, W., Auchus, R. J., Falhammar, H., Flück, C. E., Guasti, L., Huebner, A., Kortmann, B. B. M., et al. (2022) · Endocrine Reviews · doi:10.1210/endrev/bnab016 · Cited by 556 · see citing works

The role of primary cilia in the development and disease of the retina

Wheway, G., Parry, D. A., & Johnson, C. A. (2014) · Organogenesis · doi:10.4161/org.26710 · Cited by 152 · see citing works

Disease Boundaries in the Retina of Patients with Usher Syndrome Caused by<i>MYO7A</i>Gene Mutations

Jacobson, S. G., Aleman, T. S., Sumaroka, A., Cideciyan, A. V., Roman, A. J., Windsor, E. A. M., Schwartz, S. B., Rehm, H. L., & Kimberling, W. J. (2009) · Investigative Opthalmology &amp; Visual Science · doi:10.1167/iovs.08-3122 · Cited by 93 · see citing works

A novel function of Huntingtin in the cilium and retinal ciliopathy in Huntington’s disease mice

Karam, A., Tebbe, L., Weber, C., Messaddeq, N., Morlé, L., Kessler, P., Wolfrum, U., & Trottier, Y. (2015) · Neurobiology of Disease · doi:10.1016/j.nbd.2015.05.008 · Cited by 38 · see citing works

Molecular and Cellular Mechanisms of Ectodomain Shedding

Hayashida, K., Bartlett, A. H., Chen, Y., & Park, P. W. (2010) · The Anatomical Record · doi:10.1002/ar.20757 · Cited by 198 · see citing works

Crystallization and preliminary diffraction studies of the ectodomain of the envelope glycoprotein D from herpes simplex virus 1 alone and in complex with the ectodomain of the human receptor HveA

Carfı́, A., Gong, H., Lou, H., et al. (2002) · Acta Crystallographica Section D Biological Crystallography · doi:10.1107/s0907444902001270 · Cited by 35 · see citing works

The Structure of the C-Cadherin Ectodomain Resolved

Leckband, D. E. (2002) · Structure · doi:10.1016/s0969-2126(02)00783-9 · Cited by 9 · see citing works

Protein-Labeling Fluorescent Probe Reveals Ectodomain Shedding of Transmembrane Carbonic Anhydrases

Lin, F.-L., Yen, J.-T., Fang, P.-W., Xu, S.-Q., Lin, J.-C., & Tan, K. (2022) · ACS Chemical Biology · doi:10.1021/acschembio.2c00679 · Cited by 7 · see citing works

Ectodomain Shedding of ACE and ACE2 as Regulators of Their Protein Functions

Iwata, M., & Greenberg, B. (2011) · Current Enzyme Inhibition · doi:10.2174/157340811795713756 · Cited by 13 · see citing works