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A Communication Means for Totally Locked-in ALS Patients Based on Changes in Cerebral Blood Volume Measured with Near-Infrared Light
Abstract
A communication means is presented for patients with amyotrophic lateral sclerosis in totally locked-in state who are completely unable to move any part of the body and have no usual communication means. The method utilizes changes in cerebral blood volume accompanied with changes in brain activity. When a patient is asked a question and the answer to it is ‘yes’, the patient makes his or her brain active. The change in blood volume at the frontal lobe is detected with near-infrared light. The instantaneous amplitude and phase of the change are calculated, and the maximum amplitude and phase change are obtained. The answer ‘yes’ or ‘no’ of the patient is detected using a discriminant analysis with these two quantities as variables. The rate of correct detection is 80% on average.
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Birbaumer, N., Ghanayim, N., Hinterberger, T., Iversen, I., Kotchoubey, B., Kübler, A., Perelmouter, J., Taub, E., & Flor, H. (1999) · Nature · doi:10.1038/18581 · Cited by 1,577
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Brain–computer interfaces in neurological rehabilitation
Daly, J. J., & Wolpaw, J. R. (2008) · The Lancet Neurology · doi:10.1016/s1474-4422(08)70223-0 · Cited by 1,149
fNIRS-based brain-computer interfaces: a review
Naseer, N., & Hong, K.-S. (2015) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2015.00003 · Cited by 988
Brain–computer interfaces for communication and rehabilitation
Chaudhary, U., Birbaumer, N., & Ramos-Murguialday, A. (2016) · Nature Reviews Neurology · doi:10.1038/nrneurol.2016.113 · Cited by 928
Real-time fMRI neurofeedback: Progress and challenges
Sulzer, J., Haller, S., Scharnowski, F., Weiskopf, N., Birbaumer, N., Blefari, M. L., Bruehl, A. B., Cohen, L. G., deCharms, R. C., Gassert, R., et al. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.03.033 · Cited by 453
Naseer, N., & Hong, K.-S. (2013) · Neuroscience Letters · doi:10.1016/j.neulet.2013.08.021 · Cited by 301
Metadata
- Authors
- NAITO, M., MICHIOKA, Y., OZAWA, K., ITO, Y., KIGUCHI, M., & KANAZAWA, T.
- Venue
- IEICE Transactions on Information and Systems
- Published
- 2007-07-01
- Volume
- E90-D
- Issue
- 7
- Pages
- 1028-1037
- ISSN
- 0916-8532 (ISSN-L)
- 1745-1361
- OpenAlex
- W2076708394
- Cited by
- 218
- References
- 1
- FWCI
- 4.64
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: A Communication Means for Totally Locked-in ALS Patients Based on Changes in Cerebral Blood Volume Measured with Near-Infrared Light. https://app.cochat.ai/papers/10.1093/ietisy/e90-d.7.1028
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- NAITO, M., MICHIOKA, Y., OZAWA, K., ITO, Y., KIGUCHI, M., & KANAZAWA, T. (2007). A Communication Means for Totally Locked-in ALS Patients Based on Changes in Cerebral Blood Volume Measured with Near-Infrared Light. IEICE Transactions on Information and Systems. https://doi.org/10.1093/ietisy/e90-d.7.1028
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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