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Coronavirus Infection in Acute Lower Respiratory Tract Disease of Infants
Open accessAbstract
A serologic surveillance of lower respiratory tract disease in 417 hospitalized children under 18 months of age revealed infection with coronaviruses (strains OC43 and/or 229E) in 34 (8.2%). During the same interval, one of 13 control infants was infected. There were two distinct periods lasting six and 14 weeks, respectively, during which the incidence rose to as high as 18.9% of patients with lower respiratory tract disease. The incidence of coronavirus infection in patients with pneumonia and bronchiolitis was higher than the incidences of adenoviruses, influenza, parainfluenza viruses types 1 and 2, and rhinoviruses, and lower only than the incidences of parainfluenza virus type 3 and respiratory syncytial virus. Coronaviruses serologically similar or identical to strain 229E were recovered from frozen nasal washes obtained during the acute phase of pneumonia in two children.
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Citations
Cited by
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Choi, E. H., Lee, H. J., Kim, S. J., Eun, B. W., Kim, N. H., Lee, J. A., Lee, J. H., Song, E. K., Kim, S. H., Park, J. Y., et al. (2006) · Clinical Infectious Diseases · doi:10.1086/506350 · Cited by 396
The Biology and Pathogenesis of Coronaviruses
Wege, H., Siddell, S., & ter Meulen, V. (1982) · Current Topics in Microbiology and Immunology · doi:10.1007/978-3-642-68528-6_5 · Cited by 360
Liu, W., Fontanet, A., Zhang, P., Zhan, L., Xin, Z., Baril, L., Tang, F., Lv, H., & Cao, W. (2006) · The Journal of Infectious Diseases · doi:10.1086/500469 · Cited by 285
Metadata
- Authors
- McIntosh, K., Chao, R. K., Krause, H. E., Wasil, R., Mocega, H. E., & Mufson, M. A.
- Venue
- Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1974-11-01
- Volume
- 130
- Issue
- 5
- Pages
- 502-507
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2142788458
- Cited by
- 176
- References
- 0
- FWCI
- 0.58
- Type
- journal article
- Language
- en
- Open access
- bronze
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- McIntosh, K., Chao, R. K., Krause, H. E., Wasil, R., Mocega, H. E., & Mufson, M. A. (1974). Coronavirus Infection in Acute Lower Respiratory Tract Disease of Infants. Journal of Infectious Diseases. https://doi.org/10.1093/infdis/130.5.502
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