Combined effects of mobile health (mHealth) psychoeducation and the Benson relaxation technique on caregiving burden among female caregivers of patients with cancer: a randomized controlled trial
Abstract
Background: Psychoeducational and relaxation-based interventions have been shown to reduce caregiver burden; however, limited evidence exists regarding the effectiveness of combined interventions delivered via mobile health (mHealth) in resource-limited settings. This study aimed to evaluate the combined effects of mHealth-based psychoeducation and the Benson Relaxation Technique (BRT) on caregiver burden among female informal caregivers of patients with cancer. Methods: A prospective, open-ended, randomized controlled trial (1:1 allocation) was conducted from October 2024 to March 2025. In total, 102 female caregivers were randomly assigned to either the intervention or control group. Validated Bangla versions of the Zarit Burden Interview, Hospital Anxiety and Depression Scale, and WHO – Quality of Life – Brief (WHOQOL-BREF) were administered at baseline, three months, and six months. Data were analyzed using repeated-measures analysis of variance under the intention-to-treat principle. Results: The intervention group demonstrated significant reductions in caregiver burden (F = 58.4, P < .001), anxiety (F = 34.9, P < .001), and depression (F = 34.9, P < .001) over six months, compared to the control group. Significant group × time interactions were observed for overall quality of life (QOL) (P < .001) and across physical (P < .001), psychological (P < .001), social (P = .004), and environmental (P < .001) domains. Conclusion: The combined mHealth psychoeducation and BRT intervention significantly reduced caregiver burden and psychological distress, and improved QOL among female caregivers of patients with cancer. This culturally adaptable, low-cost, technology-enabled approach offers a promising strategy to support caregiver needs in low- and middle-income countries where psychosocial services are limited.
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- Authors
- Roshid, M. M., Rahman, M. M., Eity, K. F., & Okamura, H.
- Affiliations
- Hiroshima University (JP)
- East Texas A&M University (US)
- Corresponding author
- Okamura, Hitoshi
- Venue
- Japanese Journal of Clinical Oncology
- Publisher
- Oxford University Press (OUP)
- Published
- 2026-02-13
- Volume
- 56
- Issue
- 6
- Pages
- 748-756
- ISSN
- 0368-2811 (ISSN-L)
- 1465-3621
- OpenAlex
- W7128797187
- Semantic Scholar
- 0b45f3b91e356495826f5e397032ecd545e2f514
- Cited by
- 1
- References
- 29
- Citations by year
- 2026: 1
- FWCI
- 11.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Japanese Journal of Clinical Oncology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Health Professions › Pharmacy › Nursing care and research
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
- Keywords
- mobile health, psychoeducation, Benson relaxation technique, caregiver burden, women caregivers, cancer caregiving, anxiety, depression, quality of life, psychosocial interventions, resource-limited settings, culturally tailored interventions
- MeSH terms
- Adult, Aged, Anxiety, Depression, Female, Humans, Middle Aged, Neoplasms, Prospective Studies, Quality of Life, Relaxation Therapy, Stress, Psychological, Caregivers, Telemedicine
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