CoChat
Sign Up
Cited by 41

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Fish Oil (n-3) Polyunsaturated Fatty Acids Beneficially Affect Biliary Cholesterol Nucleation Time in Obese Women Losing Weight

Méndez-Sánchez, Nahum, González, Verónica, Aguayo, Patricia, Sánchez, Juan M., Tanimoto, Miguel A., Elizondo, Javier, Uribe, Misael·2001·The Journal of Nutrition
DOI 10.1093/jn/131.9.2300
Open this paper in CoChat — free account

Abstract

It has been reported that intake of (n-3) polyunsaturated fatty acids (PUFA) reduces the risk of coronary heart disease and decreases biliary cholesterol saturation in the bile of gallstone patients. We investigated the effect of n-3 PUFA on cholesterol saturation index (CSI) and nucleation time (NT) in obese subjects who were losing weight. This was a double-blind, placebo-controlled clinical trial. Obese women (n = 35) with a body mass index (BMI) > or = 30 kg/m(2), with no prior history of gallstones or cholecystectomy by ultrasound were first studied to ensure absence of stones or biliary sludge. The women were then assigned to a hypocaloric regimen [5.02 MJ (1200 kcal)/d] and to receive 1200 mg/d of ursodeoxycholic acid (UDCA), 11.3 g/d of (n-3) PUFA or a placebo for 6 wk. BMI, CSI and NT were recorded at baseline and at the end of the experimental period. BMI decreased 5.75 +/- 2.7%/mo (range, 1.5-12.42%/mo) during the experiment. The CSI did not change in any of the groups. Cholesterol NT decreased significantly in the UDCA and placebo groups, but not in the (n-3) PUFA group. None of the women had developed gallstones at 6 wk. These results suggest that (n-3) PUFA maintain the CSI and NT in obese women during rapid weight loss, which probably results in the prevention of cholesterol gallstone formation.

Overview

Integrity signals

Registry

Crossref · 10.1093/jn/131.9.2300

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Legumes, olive oil, and nuts are reported to reduce the risk of cholecystectomy.

    “Other foods reported to reduce the risk of cholecystectomy include legumes, olive oil [68], and nuts [69].”

    From Excess Body Weight and Gallstone Disease (2021) · cites this paper as [69]

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 34

  1. Kalser, 1993, Consensus development conference statement on gallstone and laparoscopic cholecystectomy, Am. J. Surg, 165, 390, 10.1016/S0002-9610(05)80929-8 · DOI
  2. Diehl, 1991, Epidemiology and natural history of gallstone disease, Gastroenterol. Clin. N. Am, 20, 1, 10.1016/S0889-8553(21)00531-8 · DOI
  3. Medina, 1983, Frecuencia de la litiasis biliar en Chile, Rev. Med. Chile, 111, 668
  4. Méndez-Sánchez, 1993, Prevalence of gallstone disease in Mexico, A necropsy study. Dig. Dis. Sci, 38, 680, 10.1007/BF01316800 · DOI
  5. Roda, 1990, Gallstone disease: a clinical lesson from epidemiology, J. Lithotripsy Stone Dis, 2, 279
  6. Méndez-Sánchez, 1998, Risk factors for gallstone disease in Mexican patients are similar to those found in Mexican-Americans, Dig. Dis. Sci, 43, 935, 10.1023/A:1018849911355 · DOI
  7. Broomfield, 1988, Effects of ursodeoxycholic acid and aspirin on the formation of lithogenic bile and gallstones during loss of weight, N. Engl. J. Med, 319, 1567, 10.1056/NEJM198812153192403 · DOI · Paper page
  8. Liddle, 1989, Gallstone formation during rapid weight reduction dieting, Arch. Intern. Med, 149, 1750, 10.1001/archinte.1989.00390080036009 · DOI · Paper page
  9. Thijs, 1992, Is gallstone disease caused by obesity or by dieting?, Am. J. Epidemiol, 135, 274, 10.1093/oxfordjournals.aje.a116281 · DOI
  10. Yang, 1992, Risk factors for gallstone formation during rapid loss of weight, Dig. Dis. Sci, 37, 912, 10.1007/BF01300390 · DOI · Paper page
  11. Méndez-Sánchez, 1996, Pathophysiology of cholesterol gallstone disease, Arch. Med. Res, 27, 433
  12. Shiffman, 1991, Gallstone formation after rapid weight loss, A prospective study in patients undergoing gastric bypass surgery for treatment of morbid obesity. Am. J. Gastroenterol, 86, 1000
  13. Wattchow, 1983, Prevalence and treatment of gallstones after gastric bypass surgery for morbid obesity, Br. Med. J, 286, 763, 10.1136/bmj.286.6367.763 · DOI
  14. Amaral, 1985, Gallbladder disease in the morbidly obese, Am. J. Surg, 149, 1, 10.1016/S0002-9610(85)80055-6 · DOI · Paper page
  15. Heshka, 1996, Obesity and risk of gallstone development on a 1200 kcal/d (5025 kJ/d) regular diet, Int. J. Obes, 20, 450
  16. Shiffman, 1995, Prophylaxis against gallstone formation with ursodeoxycholic acid in patients participating in a very low calorie diet program, Ann. Intern. Med, 122, 899, 10.7326/0003-4819-122-12-199506150-00002 · DOI · Paper page
  17. Leaf, 1988, Cardiovascular effect of n-3 fatty acids, N. Engl. J. Med, 318, 549, 10.1056/NEJM198803033180905 · DOI
  18. Boss, 1982, Cancer of the gallbladder and biliary tract in Alaskan natives, 1970–1979, J. Natl. Cancer Inst, 69, 1005
  19. Berr, 1992, Dietary n-3 polyunsaturated fatty acids decrease biliary cholesterol saturation in gallstone disease, Hepatology, 16, 960, 10.1002/hep.1840160418 · DOI · Paper page
  20. Bartlett, 1959, Phosphorous assay in column chromatography, J. Biol. Chem, 234, 466, 10.1016/S0021-9258(18)70226-3 · DOI
  21. Turley, 1978, Re-evaluation of the 3 α-hydroxysteroid dehydrogenase assay for total bile acids in bile, J. Lipid. Res, 19, 924, 10.1016/S0022-2275(20)40709-6 · DOI
  22. Carey, 1978, Critical tables for calculating the cholesterol saturation of native bile, J. Lipid. Res, 19, 945, 10.1016/S0022-2275(20)40677-7 · DOI
  23. Holan, 1979, Nucleation time: a key factor in the pathogenesis of cholesterol gallstone disease, Gastroenterology, 77, 611, 10.1016/0016-5085(79)90209-9 · DOI
  24. Winer, B. J. (1971) Statistical Principles in Experimental Design, 2nd ed. McGraw-Hill, New York, NY.
  25. Mazzella, 1991, Comparative evaluation of chenodeoxycholic and ursodeoxycholic acid in obese patients. Effect on biliary lipid metabolism during weight maintenance and weight reduction, Gastroenterology, 101, 490, 10.1016/0016-5085(91)90029-K · DOI
  26. Sahlin, 1991, Nucleation time of gallbladder bile in gallstone patients: influence of bile acid treatment, Gut, 32, 1554, 10.1136/gut.32.12.1554 · DOI
  27. Méndez-Sánchez, 1996, Prevention of gallstones during weight reduction, Ann. Intern. Med, 124, 532, 10.7326/0003-4819-124-5-199603010-00017 · DOI
  28. Festi, 1998, Gallbladder motility and gallstone formation in obese patients following very low calorie diets, Use it (fat) to lose it (well). Int. J. Obes, 22, 592
  29. Scobey, 1991, Dietary fish oil effects on biliary lipid secretion and cholesterol gallstone formation in the African green monkey, Hepatology, 14, 679
  30. Booker, 1990, Effects of dietary fish oil on biliary phospholipids and prostaglandin synthesis in the cholesterol-fed prairie dog, Lipids, 25, 27, 10.1007/BF02562424 · DOI
  31. Abei, M., Shimizu, M., Yashushi M., Shoda, Y. & Tanaka, N. (2000) Fish oil (eicosapentaenoic acid) inhibits two pathways of mucus glycoprotein secretion in gallbladder epithelial cells. Gastroenterology 118: A714 (abs.). · DOI
  32. Smit, 1991, Dietary fish oil-induced changes in intrahepatic cholesterol transport and bile acid synthesis in rats, J. Clin. Investig, 88, 943, 10.1172/JCI115397 · DOI
  33. Marks, 1996, Effects of ursodiol or ibuprofen on contraction of gallbladder and bile among obese patients during weight loss, Dig. Dis. Sci, 41, 242, 10.1007/BF02093811 · DOI
  34. Sitzmann, 1990, Cholecystokinin prevents parenteral nutrition-induced biliary sludge in humans, Surg. Gynecol. Obstet, 170, 25

Cited by

Sorted by citations

Metadata

Authors
Méndez-Sánchez, N., González, V., Aguayo, P., Sánchez, J. M., Tanimoto, M. A., Elizondo, J., & Uribe, M.
Venue
The Journal of Nutrition
Publisher
Elsevier BV
Published
2001-09
Volume
131
Issue
9
Pages
2300-2303
ISSN
0022-3166
DOI
10.1093/jn/131.9.2300
Cited by
41
References
1
Language
en
Licence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review