The DOI matches its Crossref record.
Colon Cancer and Dietary Fat, Phosphate, and Calcium: A Hypothesis
Abstract
Increased dietary fat was suggested to promote colon cancer by increasing the levels of free ionized fatty acids and bile acids in the colon contents. In the presence of calcium ions the irritating and toxic effects of the free acids on colon epithelial cells could be reduced by being converted to insoluble calcium soaps. The level of supplementary dietary calcium to supply adequate calcium and thus reduce the potential toxicity of dietary fat was considered.
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Citations
Cited by
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Sidransky, D., Tokino, T., Hamilton, S. R., Kinzler, K. W., Levin, B., Frost, P., & Vogelstein, B. (1992) · Science · doi:10.1126/science.1566048 · Cited by 698
Nutrients, foods, and colorectal cancer prevention
Song, M., Garrett, W. S., & Chan, A. T. (2015) · Gastroenterology · doi:10.1053/j.gastro.2014.12.035 · Cited by 700
Vitamin D for Cancer Prevention: Global Perspective
Garland, C. F., Gorham, E. D., Mohr, S. B., & Garland, F. C. (2009) · Annals of Epidemiology · doi:10.1016/j.annepidem.2009.03.021 · Cited by 438
Cormick, G., & Belizán, J. M. (2019) · Nutrients · doi:10.3390/nu11071606 · Cited by 388
Calcium Intake and Risk of Colon Cancer in Women and Men
Wu, K. (2002) · CancerSpectrum Knowledge Environment · doi:10.1093/jnci/94.6.437 · Cited by 363
Metadata
- Venue
- JNCI: Journal of the National Cancer Institute
- Publisher
- Oxford University Press (OUP)
- Published
- 1984-06
- Volume
- 72
- Issue
- 6
- Pages
- 1323-5
- ISSN
- 0027-8874 (ISSN-L)
- 1460-2105
- OpenAlex
- W1925555331
- Cited by
- 551
- References
- 0
- FWCI
- 24.48
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Colon Cancer and Dietary Fat, Phosphate, and Calcium: A Hypothesis. https://app.cochat.ai/papers/10.1093/jnci/72.6.1323
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- Colon Cancer and Dietary Fat, Phosphate, and Calcium: A Hypothesis. (1984). JNCI: Journal of the National Cancer Institute. https://doi.org/10.1093/jnci/72.6.1323
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
