The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.
HDA6 is required for jasmonate response, senescence and flowering in Arabidopsis
Abstract
Post-translational modifications of histones, including acetylation, play a key role in modulating dynamic changes in chromatin structure and gene activity. Histone acetylation is modulated through the action of histone acetyltransferases and deacetylases. HDA6 is a RPD3-type histone deacetylase in Arabidopsis. The Arabidopsis HDA6 mutant, axe1-5, and HDA6 RNA-interfering (HDA6-RNAi) plants displayed higher levels of acetylated H3 compared with wild-type, suggesting that HDA6 affects histone acetylation levels globally. The expression of the jasmonate responsive genes, PDF1.2, VSP2, JIN1, and ERF1, was down-regulated in axe1-5 and HDA6-RNAi plants. Furthermore, axe1-5 and HDA6-RNAi plants displayed increased leaf longevity compared with the wild type. The expression of the senescence-associated genes, SAG12 and SEN4, was down-regulated in the axe1-5 and HDA6-RNAi plants. In addition, axe1-5 and HDA6-RNAi plants displayed late-flowering. The expression of FLC was up-regulated and hyperacetylated in axe1-5 and HDA6-RNAi plants, suggesting that HDA6 is required to deacetylate FLC chromatin and thereby repress its expression. Our results suggest that HDA6 is involved in jasmonate response, senescence, and flowering in Arabidopsis.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Floral dip: a simplified method forAgrobacterium‐mediated transformation ofArabidopsis thaliana
Clough, S. J., & Bent, A. F. (1998) · The Plant Journal · doi:10.1046/j.1365-313x.1998.00343.x · Cited by 21,934
Porra, R. J., Thompson, W. A., & Kriedemann, P. E. (1989) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(89)80347-0 · Cited by 5,992
A Mammalian Histone Deacetylase Related to the Yeast Transcriptional Regulator Rpd3p
Taunton, J., Hassig, C. A., & Schreiber, S. L. (1996) · Science · doi:10.1126/science.272.5260.408 · Cited by 1,829
Lorenzo, O., Piqueras, R., Sánchez-Serrano, J. J., & Solano, R. (2003) · The Plant Cell · doi:10.1105/tpc.007468 · Cited by 1,405
Lorenzo, O., Chico, J. M., Saénchez-Serrano, J. J., & Solano, R. (2004) · The Plant Cell · doi:10.1105/tpc.022319 · Cited by 1,344
Arabidopsis : a laboratory manual
Weigel, D., & Glazebrook, J. (2002) · Cited by 995
Control of Flowering Time: Interacting Pathways as a Basis for Diversity
Mouradov, A., Cremer, F., & Coupland, G. (2002) · The Plant Cell · doi:10.1105/tpc.001362 · Cited by 994
Making Sense of Senescence (Molecular Genetic Regulation and Manipulation of Leaf Senescence)
Gan, S., & Amasino, R. M. (1997) · Plant Physiology · doi:10.1104/pp.113.2.313 · Cited by 902
Pandey, R. (2002) · Nucleic Acids Research · doi:10.1093/nar/gkf660 · Cited by 790
Evidence Supporting a Role of Jasmonic Acid in Arabidopsis Leaf Senescence
He, Y., Fukushige, H., Hildebrand, D. F., & Gan, S. (2002) · PLANT PHYSIOLOGY · doi:10.1104/pp.010843 · Cited by 709
Cited by
Wasternack, C., & Hause, B. (2013) · Annals of Botany · doi:10.1093/aob/mct067 · Cited by 2,629
Epigenetic regulation of stress responses in plants
Chinnusamy, V., & Zhu, J.-K. (2009) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2008.12.006 · Cited by 1,162
Kazan, K., & Manners, J. M. (2013) · Molecular Plant · doi:10.1093/mp/sss128 · Cited by 1,081
Next-Generation Systemic Acquired Resistance
Luna, E., Bruce, T. J. A., Roberts, M. R., Flors, V., & Ton, J. (2012) · Plant Physiology · doi:10.1104/pp.111.187468 · Cited by 721
Modularity in Jasmonate Signaling for Multistress Resilience
Howe, G. A., Major, I. T., & Koo, A. J. (2018) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042817-040047 · Cited by 697
Metadata
- Authors
- Wu, K., Zhang, L., Zhou, C., Yu, C.-W., & Chaikam, V.
- Venue
- Journal of Experimental Botany
- Publisher
- Oxford University Press (OUP)
- Published
- 2008-02-01
- Volume
- 59
- Issue
- 2
- Pages
- 225-234
- ISSN
- 0022-0957 (ISSN-L)
- 1460-2431
- OpenAlex
- W2147061516
- Cited by
- 326
- References
- 50
- FWCI
- 21.98
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: HDA6 is required for jasmonate response, senescence and flowering in Arabidopsis. https://app.cochat.ai/papers/10.1093/jxb/erm300
- The paper
- Wu, K., Zhang, L., Zhou, C., Yu, C.-W., & Chaikam, V. (2008). HDA6 is required for jasmonate response, senescence and flowering in Arabidopsis. Journal of Experimental Botany. https://doi.org/10.1093/jxb/erm300
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
