The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Molecular Phylogeny and Divergence Times of Deuterostome Animals
Open accessAbstract
The phylogenetic relationships among deuterostome animals have been debated for many years, and a diversity of hypotheses have been proposed based on both morphological and molecular data. Here we have assembled sequences of 217 nuclear-encoded proteins to address specific questions concerning their relationships and times of origin. We recovered significant support for urochordates as the closest relative of vertebrates with an analysis of 59 proteins (17,400 amino acids) and suggest that the basal position of urochordates found in previous molecular studies may have been the result of long-branch attraction biases. Our results also support Ambulacraria, the pairing of hemichordates with echinoderms (nine proteins; 2,382 amino acids), and Cyclostomata, the pairing of lampreys with hagfish (25 proteins; 6,895 amino acids). In addition, 325 shared proteins (102,110 amino acids) were obtained from the complete genomes of six vertebrates and a urochordate for phylogenetic analysis and divergence time estimation. An evolutionary timescale was estimated using a local (Bayesian) molecular clock method. We found that most major lineages of deuterostomes arose prior to the Cambrian Explosion of fossils (approximately 520 MYA) and that several lineages had originated before periods of global glaciation in the Precambrian.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The sequence of the human genome
Venter, J. C., Adams, M. D., Myers, E. W., Li, P. W., Mural, R. J., Sutton, G. G., Smith, H. O., Yandell, M., Evans, C. A., Holt, R. A., et al. (2001) · Science · doi:10.1126/science.1058040 · Cited by 13,909
Initial sequencing and comparative analysis of the mouse genome
Mouse Genome Sequencing Consortium (2002) · Nature · doi:10.1038/nature01262 · Cited by 7,187
Multiple Comparisons of Log-Likelihoods with Applications to Phylogenetic Inference
Shimodaira, H., & Hasegawa, M. (1999) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a026201 · Cited by 4,237
International Chicken Genome Sequencing Consortium (2004) · Nature · doi:10.1038/nature03154 · Cited by 2,750
A Neoproterozoic Snowball Earth
Hoffman, P. F., Kaufman, A. J., Halverson, G. P., & Schrag, D. P. (1998) · Science · doi:10.1126/science.281.5381.1342 · Cited by 2,693
Quartet Puzzling: A Quartet Maximum-Likelihood Method for Reconstructing Tree Topologies
Strimmer, K., & von Haeseler, A. (1996) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a025664 · Cited by 2,531
Jaillon, O., Aury, J.-M., Brunet, F., Petit, J.-L., Stange-Thomann, N., Mauceli, E., Bouneau, L., Fischer, C., Ozouf-Costaz, C., Bernot, A., et al. (2004) · Nature · doi:10.1038/nature03025 · Cited by 1,966
A molecular timescale for vertebrate evolution
Kumar, S., & Hedges, S. B. (1998) · Nature · doi:10.1038/31927 · Cited by 1,936
Self-citationThe Draft Genome of Ciona intestinalis : Insights into Chordate and Vertebrate Origins
Dehal, P., Satou, Y., Campbell, R. K., Chapman, J., Degnan, B., De Tomaso, A., Davidson, B., Di Gregorio, A., Gelpke, M., Goodstein, D. M., et al. (2002) · Science · doi:10.1126/science.1080049 · Cited by 1,641 · cited 1×
“…(Gibbs et al. 2004), the domestic fowl Gallus gallus (version 1.1a) (Hillier et al. 2004), the pufferfish Takifugu rubripes (version 2c.1) (Aparicio et al. 2002) and Tetraodon nigroviridis (version 1a.1) (Jaillon et al. 2004), and the tunicate Ciona intestinalis (version 1.0) (Dehal et al. 2002).”
BackgroundInfluentialU-Pb Ages from the Neoproterozoic Doushantuo Formation, China
Condon, D., Zhu, M., Bowring, S., Wang, W., Yang, A., & Jin, Y. (2005) · Science · doi:10.1126/science.1107765 · Cited by 1,329
Cited by
Tunicates and not cephalochordates are the closest living relatives of vertebrates
Delsuc, F., Brinkmann, H., Chourrout, D., & Philippe, H. (2006) · Nature · doi:10.1038/nature04336 · Cited by 1,651
Evolution of the vertebrate eye: Opsins, photoreceptors, retina and eye cup
Lamb, T. D., Collin, S. P., & Pugh, E. N. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2283 · Cited by 454
Evolution of the Rho Family of Ras-Like GTPases in Eukaryotes
Boureux, A., Vignal, E., Faure, S., & Fort, P. (2007) · Molecular Biology and Evolution · doi:10.1093/molbev/msl145 · Cited by 447
Peterson, K. J., Cotton, J. A., Gehling, J. G., & Pisani, D. (2008) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2007.2233 · Cited by 313
On the Age of Eukaryotes: Evaluating Evidence from Fossils and Molecular Clocks
Eme, L., Sharpe, S. C., Brown, M. W., & Roger, A. J. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a016139 · Cited by 287
Metadata
- Authors
- Blair, J. E., & Hedges, S. B.
- Venue
- Molecular Biology and Evolution
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-07-27
- Volume
- 22
- Issue
- 11
- Pages
- 2275-2284
- ISSN
- 0737-4038 (ISSN-L)
- 1537-1719
- OpenAlex
- W1975553093
- Cited by
- 449
- References
- 30
- FWCI
- 38.00
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Molecular Phylogeny and Divergence Times of Deuterostome Animals. https://app.cochat.ai/papers/10.1093/molbev/msi225
- The paper
- Blair, J. E., & Hedges, S. B. (2005). Molecular Phylogeny and Divergence Times of Deuterostome Animals. Molecular Biology and Evolution. https://doi.org/10.1093/molbev/msi225
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
