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The nucleotide sequence of the rat cytoplasmic β–actin gene
Open accessAbstract
The nucleotide sequence of the rat beta-actin gene was determined. The gene codes for a protein identical to the bovine beta-actin. It has a large intron in the 5' untranslated region 6 nucleotides upstream from the initiator ATG, and 4 introns in the coding region at codons specifying amino acids 41/42, 121/122, 267, and 327/328. Unlike the skeletal muscle actin gene and many other actin genes, the beta-actin gene lacks the codon for Cys between the initiator ATG and the codon for the N-terminal amino acid of the mature protein. The usage of synonymous codons in the beta-actin gene is nonrandom, and is similar to that in the rat skeletal muscle and other vertebrate actin genes, but differs from the codon usage in yeast and soybean actin genes.
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Cites
A rapid alkaline extraction procedure for screening recombinant plasmid DNA
Birnboim, H. C., & Doly, J. (1979) · Nucleic Acids Research · doi:10.1093/nar/7.6.1513 · Cited by 14,686
Cited by
Ponte, P., Ng, S.-Y., Engel, J., Gunning, P., & Kedes, L. (1984) · Nucleic Acids Research · doi:10.1093/nar/12.3.1687 · Cited by 936
Rath, H. C., Herfarth, H. H., Ikeda, J. S., Grenther, W. B., Hamm, T. E., Balish, E., Taurog, J. D., Hammer, R. E., Wilson, K. H., & Sartor, R. B. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118878 · Cited by 834
FGF5 as a regulator of the hair growth cycle: Evidence from targeted and spontaneous mutations
Hébert, J. M., Rosenquist, T., Götz, J., & Martin, G. R. (1994) · Cell · doi:10.1016/0092-8674(94)90276-3 · Cited by 589
Yamada, J., Okabe, A., Toyoda, H., Kilb, W., Luhmann, H. J., & Fukuda, A. (2004) · The Journal of Physiology · doi:10.1113/jphysiol.2004.062471 · Cited by 572
Sorting of β-Actin mRNA and Protein to Neurites and Growth Cones in Culture
Bassell, G. J., Zhang, H., Byrd, A. L., Femino, A. M., Singer, R. H., Taneja, K. L., Lifshitz, L. M., Herman, I. M., & Kosik, K. S. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-01-00251.1998 · Cited by 448
Metadata
- Authors
- Nudel, U., Zakut, R., Shani, M., Neuman, S., Levy, Z., & Yaffe, D.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 1983
- Volume
- 11
- Issue
- 6
- Pages
- 1759-1771
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W2114882367
- Cited by
- 1,037
- References
- 1
- FWCI
- 8.43
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Nudel, U., Zakut, R., Shani, M., Neuman, S., Levy, Z., & Yaffe, D. (1983). The nucleotide sequence of the rat cytoplasmic β–actin gene. Nucleic Acids Research. https://doi.org/10.1093/nar/11.6.1759
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