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Cited by 473

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Escherichia coli promoter sequences predict in vitro RNA polymerase selectivity

Open access
Mulligan, Martin E., Hawley, Diane K., Entriken, Robert, McClure, William R.·1984·Nucleic Acids Research

Abstract

We describe a simple algorithm for computing a homology score for Escherichia coli promoters based on DNA sequence alone. The homology score was related to 31 values, measured in vitro, of RNA polymerase selectivity, which we define as the product KBk2, the apparent second order rate constant for open complex formation. We found that promoter strength could be predicted to within a factor of +/-4.1 in KBk2 over a range of 10(4) in the same parameter. The quantitative evaluation was linked to an automated (Apple II) procedure for searching and evaluating possible promoters in DNA sequence files.

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Crossref · 10.1093/nar/12.1part2.789

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Metadata

Authors
Mulligan, M. E., Hawley, D. K., Entriken, R., & McClure, W. R.
Venue
Nucleic Acids Research
Published
1984
Volume
12
Issue
1Part2
Pages
789-800
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W2031121939
Cited by
473
References
7
FWCI
23.09
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Escherichia coli promoter sequences predict in vitro RNA polymerase selectivity. https://app.cochat.ai/papers/10.1093/nar/12.1part2.789
The paper
Mulligan, M. E., Hawley, D. K., Entriken, R., & McClure, W. R. (1984). Escherichia coli promoter sequences predict in vitro RNA polymerase selectivity. Nucleic Acids Research. https://doi.org/10.1093/nar/12.1part2.789

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.