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Cited by 411

The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.

Sequence Analysis and Characterization of Stutter Products at the Tetranucleotide Repeat Locus VWA

Open access
Walsh, P. S., Fildes, N. J., Reynolds, R.·1996·Nucleic Acids Research

Abstract

The PCR amplification of tetranucleotide short tandem repeat (STR) loci typically produces a minor product band 4 bp shorter than the corresponding main allele band; this is referred to as the stutter band. Sequence analysis of the main and stutter bands for two sample alleles of the STR locus vWA reveals that the stutter band lacks one repeat unit relative to the main allele. Sequencing results also indicate that the number and location of the different 4 bp repeat units vary between samples containing a typical verses low proportion of stutter product. The results also suggest that the proportion of stutter product relative to the main allele increases as the number of uninterrupted core repeat units increases. The sequence analysis and results obtained using various DNA polymerases appear to support the slipped strand displacement model as a potential explanation for how these stutter products are generated.

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Metadata

Authors
Walsh, P. S., Fildes, N. J., & Reynolds, R.
Venue
Nucleic Acids Research
Published
1996-07-01
Volume
24
Issue
14
Pages
2807-2812
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W2029609095
Cited by
411
References
21
FWCI
3.21
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Sequence Analysis and Characterization of Stutter Products at the Tetranucleotide Repeat Locus VWA. https://app.cochat.ai/papers/10.1093/nar/24.14.2807
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Walsh, P. S., Fildes, N. J., & Reynolds, R. (1996). Sequence Analysis and Characterization of Stutter Products at the Tetranucleotide Repeat Locus VWA. Nucleic Acids Research. https://doi.org/10.1093/nar/24.14.2807

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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