The DOI matches its Crossref record; 59 of the 59 references it cites were found in a registry or an index.
The repertoire of DNA-binding transcriptional regulators in Escherichia coli K-12
Open accessAbstract
Using a combination of several approaches we estimated and characterized a total of 314 regulatory DNA-binding proteins in Escherichia coli, which might represent its minimal set of transcription factors. The collection is comprised of 35% activators, 43% repressors and 22% dual regulators. Within many regulatory protein families, the members are homogeneous in their regulatory roles, physiology of regulated genes, regulatory function, length and genome position, showing that these families have evolved homogeneously in prokaryotes, particularly in E.coli. This work describes a full characterization of the repertoire of regulatory interactions in a whole living cell. This repertoire should contribute to the interpretation of global gene expression profiles in both prokaryotes and eukaryotes.
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A census of human transcription factors: function, expression and evolution
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Metadata
- Authors
- Perez-Rueda, E.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2000-04-15
- Volume
- 28
- Issue
- 8
- Pages
- 1838-1847
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W2136913687
- Cited by
- 309
- References
- 59
- FWCI
- 6.31
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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