The complete genome sequence of the gastric pathogen Helicobacter pylori

Escherichia coli and Salmonella :cellular and molecular biology

Neidhardt, F. C. (1996) · ASM Press eBooks · Cited by 8,230 · see citing works

Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd

Fleischmann, R. D., Adams, M. D., White, O. R., Clayton, R. A., Kirkness, E. F., Kerlavage, A. R., Bult, C. J., Tomb, J.-F., Dougherty, B. A., Merrick, J. M., et al. (1995) · Science · doi:10.1126/science.7542800 · Cited by 5,641 · see citing works

Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites

Nielsen, H., Engelbrecht, J., Brunak, S., & von HEIJNE, G. (1997) · Protein Engineering Design and Selection · doi:10.1093/protein/10.1.1 · Cited by 5,324 · see citing works

UNIDENTIFIED CURVED BACILLI ON GASTRIC EPITHELIUM IN ACTIVE CHRONIC GASTRITIS

ROBINWARREN, J. (1983) · The Lancet · doi:10.1016/s0140-6736(83)92719-8 · Cited by 3,597 · see citing works

The Minimal Gene Complement of <i>Mycoplasma genitalium</i>

Fraser, C. M., Gocayne, J. D., White, O., Adams, M. D., Clayton, R. A., Fleischmann, R. D., Bult, C. J., Kerlavage, A. R., Sutton, G., Kelley, J. M., et al. (1995) · Science · doi:10.1126/science.270.5235.397 · Cited by 2,545 · see citing works

Complete Genome Sequence of the Methanogenic Archaeon, Methanococcus jannaschii

Bult, C. J., White, O. R., Olsen, G. J., Zhou, L., Fleischmann, R. D., Sutton, G. G., Blake, J. A., Fitzgerald, L. M., Clayton, R. A., Gocayne, J. D., et al. (1996) · Science · doi:10.1126/science.273.5278.1058 · Cited by 2,086 · see citing works

cag , a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors

Censini, S., Lange, C., Xiang, Z., Crabtree, J. E., GHIARA, P., Borodovsky, M. Y., Rappuoli, R., & Covacci, A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.25.14648 · Cited by 1,872 · see citing works

Escherichia coli and Salmonella.

Neidhart, F. C. (1996) · Cited by 1,584 · see citing works

Mosaicism in Vacuolating Cytotoxin Alleles of Helicobacter pylori

Atherton, J. C., Cao, P., Peek, R. M., Tummuru, M. K. R., Blaser, M. J., & Cover, T. L. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.30.17771 · Cited by 1,564 · see citing works

Molecular biology of microbial ureases

Mobley, H. L. T., Island, M. D., & Hausinger, R. P. (1995) · Microbiological Reviews · doi:10.1128/mr.59.3.451-480.1995 · Cited by 1,471 · see citing works

Attachment of Helicobacter pylori to Human Gastric Epithelium Mediated by Blood Group Antigens

Borén, T., Falk, P. G., Roth, K. A., Larson, G., & Normark, S. J. (1993) · Science · doi:10.1126/science.8018146 · Cited by 1,185 · see citing works

TopPred II: an improved software for membrane protein structure predictions

Claros, M. G., & von HEIJNE, G. (1994) · Computer applications in the biosciences · doi:10.1093/bioinformatics/10.6.685 · Cited by 939 · see citing works

Adaptive evolution of highly mutable loci in pathogenic bacteria

Moxon, E. R., Rainey, P. B., Nowak, M. A., & Lenski, R. E. (1994) · Current Biology · doi:10.1016/s0960-9822(00)00005-1 · Cited by 755 · see citing works

Helicobacter pylori picB, a homologue of the Bordetella pertussis toxin secretion protein, is required for induction of IL‐8 in gastric epithelial cells

Tummuru, M. K. R., Sharma, S., & Blaser, M. J. (1995) · Molecular Microbiology · doi:10.1111/j.1365-2958.1995.18050867.x · Cited by 391 · see citing works

Functions of the gene products of Escherichia coli

Riley, M. A. (1993) · Microbiological Reviews · doi:10.1128/mr.57.4.862-952.1993 · Cited by 367 · see citing works

Phase variation of gonococcal pili by frameshift mutation in pilC, a novel gene for pilus assembly.

Jonsson, A., Nyberg, G., & Normark, S. J. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07970.x · Cited by 300 · see citing works

Helicobacter pylori and gastric acid: Biological and therapeutic implications

McGowan, C., Cover, T. L., & Blaser, M. (1996) · Gastroenterology · doi:10.1053/gast.1996.v110.pm8608904 · Cited by 227 · see citing works

EcoCyc: Encyclopedia of Escherichia coli genes and metabolism

Karp, P. D. (1998) · Nucleic Acids Research · doi:10.1093/nar/26.1.50 · Cited by 221 · see citing works

Building bridges: disulphide bond formation in the cell

Bardwell, J. C. A. (1994) · Molecular Microbiology · doi:10.1111/j.1365-2958.1994.tb01281.x · Cited by 215 · see citing works

Adaptation of a conjugal transfer system for the export of pathogenic macromolecules

Winans, S. C., Burns, D., & Christie, P. J. (1996) · Trends in Microbiology · doi:10.1016/0966-842x(96)81513-7 · Cited by 190 · see citing works

tRNA-dependent asparagine formation

Curnow, A. W., Ibba, M., & Söll, D. G. (1996) · Nature · doi:10.1038/382589b0 · Cited by 155 · see citing works

Helicobacter pylori infection, a paradigm for chronic mucosal inflammation: pathogenesis and implications for eradication and prevention.

Cover, T. L., & Blaser, M. J. (1996) · PubMed · Cited by 149 · see citing works

Determinants of Helicobacter pylori pathogenicity.

Labigne, A., & Reuse, H. D. (1996) · PubMed · Cited by 142 · see citing works

Identification of carboxylation enzymes and characterization of a novel four-subunit pyruvate:flavodoxin oxidoreductase from Helicobacter pylori

Hughes, N. J., Chalk, P. A., Clayton, C. L., & Kelly, D. J. (1995) · Journal of Bacteriology · doi:10.1128/jb.177.14.3953-3959.1995 · Cited by 122 · see citing works

Characterization of repetitive DNA in the Mycoplasma genitalium genome: possible role in the generation of antigenic variation.

Peterson, S. N., Bailey, C. C., Jensen, J. S., Borre, M. B., King, E. S., Bott, K. F., & Hutchison, C. A. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.25.11829 · Cited by 112 · see citing works

Adaptive mutation and cocolonization during Helicobacter pylori infection of gnotobiotic piglets

Akopyants, N. S., Eaton, K. A., & Berg, D. E. (1995) · Infection and Immunity · doi:10.1128/iai.63.1.116-121.1995 · Cited by 105 · see citing works

Intrinsic and extrinsic approaches for detecting genes in a bacterial genome

Borodovsky, M. Y., Rudd, K. E., & Koonin, E. V. (1994) · Nucleic Acids Research · doi:10.1093/nar/22.22.4756 · Cited by 104 · see citing works

Cloning and Membrane Topology of a P type ATPase from Helicobacter pylori

Melchers, K., Weitzenegger, T., Buhmann, A., Steinhilber, W., Sachs, G. M., & Schäfer, K. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.1.446 · Cited by 100 · see citing works

The role of lipopolysaccharide in Helicobacter pylori pathogenesis.

Moran, A. P. (1996) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.1996.22164004.x · Cited by 97 · see citing works

Hydrophobic patches on protein subunit interfaces: Characteristics and prediction

Lijnzaad, P., & Argos, P. (1997) · Proteins Structure Function and Bioinformatics · doi:10.1002/(sici)1097-0134(199707)28:3 · Cited by 86 · see citing works

Paracrystalline inclusions of a novel ferritin containing nonheme iron, produced by the human gastric pathogen Helicobacter pylori: evidence for a third class of ferritins

Frazier, B. A., Pfeifer, J. D., Russell, D. G., Falk, P., Olsén, A., Hammar, M., Westblom, T. U., & Normark, S. J. (1993) · Journal of Bacteriology · doi:10.1128/jb.175.4.966-972.1993 · Cited by 85 · see citing works

Optimized BlaM‐transposon shuttle mutagenesis of Helicobacter pylori allows the identification of novel genetic loci involved in bacterial virulence

Odenbreit, S., Till, M., & Haas, R. (1996) · Molecular Microbiology · doi:10.1111/j.1365-2958.1996.tb02623.x · Cited by 79 · see citing works

Identification of four new prokaryotic bacterioferritins, from Helicobacter pylori, Anabaena variabilis, Bacillus subtilis and Treponema pallidum, by analysis of gene sequences

Evans, D. J., Evans, D. G., Lampert, H. C., & Nakano, H. (1995) · Gene · doi:10.1016/0378-1119(94)00774-m · Cited by 77 · see citing works

Impact of Infection by Helicobacter pylori on the Risk and Severity of Endemic Cholera

Clemens, J. D., Albert, M. J., Rao, M. R., Qadri, F., Huda, S. N., Kay, B. A., LOON, F. P. L. V., Sack, D. A., PRADHAN, B., & Sack, R. B. (1995) · The Journal of Infectious Diseases · doi:10.1093/infdis/171.6.1653 · Cited by 74 · see citing works

Aminoacid utilization by Helicobacter pylori

Mendz, G. L., & Hazell, S. L. (1995) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/1357-2725(95)00069-2 · Cited by 71 · see citing works

MacPattern: protein pattern searching on the Apple Macintosh

Fuchs, R. (1991) · Computer applications in the biosciences · doi:10.1093/bioinformatics/7.1.105 · Cited by 66 · see citing works

Isolation and characterization of a conserved porin protein from Helicobacter pylori

Doig, P. C., Exner, M. M., Hancock, R. E. W., & Trevor J. TRUST (1995) · Journal of Bacteriology · doi:10.1128/jb.177.19.5447-5452.1995 · Cited by 63 · see citing works

The complex flagella of gastric Helicobacter species

Suerbaum, S. (1995) · Trends in Microbiology · doi:10.1016/s0966-842x(00)88913-1 · Cited by 63 · see citing works

[42] Posttranslational processing of type IV prepilin and homologs by PilD of Pseudomonas aeruginosa

Strom, M. S., Nunn, D. N., & Lory, S. (1994) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(94)35168-6 · Cited by 56 · see citing works

Capacity of Helicobacter pylori to generate ionic gradients at low pH is similar to that of bacteria which grow under strongly acidic conditions

Matin, A., Zychlinsky, E., Keyhan, M., & Sachs, G. M. (1996) · Infection and Immunity · doi:10.1128/iai.64.4.1434-1436.1996 · Cited by 38 · see citing works

EcoCyc: Enyclopedia of Escherichia coli Genes and Metabolism

Karp, P. D., Riley, M. A., Paley, S., Pellegrini-Toole, A., & Krummenacker, M. (1997) · Nucleic Acids Research · doi:10.1093/nar/25.1.43 · Cited by 38 · see citing works

Molecular structures that influence the immunomodulatory properties of the lipid A and inner core region oligosaccharides of bacterial lipopolysaccharides

Baker, P. J., Hrabă, T., Taylor, C. E., Stashak, P. W., Fauntleroy, M. B., Zähringer, U., Takayama, K., Sievert, T. R., Hronowski, X. L., & Cotter, R. J. (1994) · Infection and Immunity · doi:10.1128/iai.62.6.2257-2269.1994 · Cited by 31 · see citing works

Bacterial chromosome origins of replication

Marczynski, G. T., & Shapiro, L. (1993) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(05)80098-x · Cited by 30 · see citing works

How does Helicobacter pylori cause duodenal ulcer disease: The bug, the host, or both?

Go, M. F., & Graham, D. Y. (1994) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.1994.tb01294.x · Cited by 28 · see citing works

The sequence of the human genome

Venter, J. C., Adams, M. D., Myers, E. W., Li, P. W., Mural, R. J., Sutton, G. G., Smith, H. O., Yandell, M., Evans, C. A., Holt, R. A., et al. (2001) · Science · doi:10.1126/science.1058040 · Cited by 13,909 · see citing works

Versatile and open software for comparing large genomes

Kurtz, S., Phillippy, A., Delcher, A. L., Smoot, M., Shumway, M., Antonescu, C., & Salzberg, S. L. (2004) · Genome Biology · doi:10.1186/gb-2004-5-2-r12 · Cited by 5,254 · see citing works

Molecular Basis of Bacterial Outer Membrane Permeability Revisited

Nikaido, H. (2003) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.67.4.593-656.2003 · Cited by 4,316 · see citing works

The complete genome sequence of the gram-positive bacterium Bacillus subtilis.

Kunst, F., Ogasawara, N., Moszer, I., Albertini, A. M., Alloni, G., Azevedo, V., Bertero, M. G., Bessières, P., Bolotin, A., Borchert, S., et al. (1997) · Nature · doi:10.1038/36786 · Cited by 3,679 · see citing works

A Genomic Perspective on Protein Families

Tatusov, R. L., Koonin, E. V., & Lipman, D. J. (1997) · Science · doi:10.1126/science.278.5338.631 · Cited by 3,552 · see citing works

Helicobacter pylori Infection

Suerbaum, S., & Michetti, P. (2002) · New England Journal of Medicine · doi:10.1056/nejmra020542 · Cited by 2,984 · see citing works

Pathogenesis of <i>Helicobacter pylori</i> Infection

Kusters, J. G., van Vliet, A. H. M., & Kuipers, E. J. (2006) · Clinical Microbiology Reviews · doi:10.1128/cmr.00054-05 · Cited by 2,526 · see citing works

GeneMarkS: a self-training method for prediction of gene starts in microbial genomes. Implications for finding sequence motifs in regulatory regions.

Besemer, J., Lomsadze, A., & Borodovsky, M. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.12.2607 · Cited by 2,343 · see citing works

Evolution by gene duplication: An update

Zhang, J. (2003) · Trends in Ecology &amp; Evolution · doi:10.1016/s0169-5347(03)00033-8 · Cited by 2,201 · see citing works

Epidemiology of gastric cancer

Crew, K. D., & Neugut, A. I. (2006) · World Journal of Gastroenterology · doi:10.3748/wjg.v12.i3.354 · Cited by 2,118 · see citing works

Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi

Fraser, C. M., Casjens, S., Huang, W. M., Sutton, G. G., Clayton, R. A., Lathigra, R. B., White, O. R., Ketchum, K. A., Dodson, R. J., Hickey, E. K., et al. (1997) · Nature · doi:10.1038/37551 · Cited by 2,083 · see citing works

The thioredoxin antioxidant system

Lu, J., & Holmgren, A. (2014) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.07.036 · Cited by 2,055 · see citing works

The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences

Parkhill, J., Wren, B. W., Mungall, K., Ketley, J. M., Churcher, C. M., Basham, D., Chillingworth, T., Davies, R. M., Feltwell, T., Holroyd, S. A., et al. (2000) · Nature · doi:10.1038/35001088 · Cited by 1,966 · see citing works

Molecular Biology and Pathogenicity of Mycoplasmas

Razin, S., Yogev, D., & Naot, Y. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.4.1094-1156.1998 · Cited by 1,930 · see citing works

Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori

Alm, R. A., Ling, L.-S. L., Moir, D. T., King, B. L., Brown, E. D., Doig, P. C., Smith, D. R., Noonan, B., Guild, B. C., deJonge, B. L., et al. (1999) · Nature · doi:10.1038/16495 · Cited by 1,893 · see citing works

Helicobacter pylori and gastrointestinal tract adenocarcinomas

Peek, R. M., & Blaser, M. J. (2002) · Nature reviews. Cancer · doi:10.1038/nrc703 · Cited by 1,807 · see citing works

The genome sequence of Rickettsia prowazekii and the origin of mitochondria

Andersson, S. G. E., Zomorodipour, A., Andersson, J. O., Sicheritz-Pontén, T., Alsmark, U. C. M., Podowski, R. M., Näslund, A. K., Eriksson, A.-S., Winkler, H. H., & Kurland, C. G. (1998) · Nature · doi:10.1038/24094 · Cited by 1,697 · see citing works

The Challenge of Efflux-Mediated Antibiotic Resistance in Gram-Negative Bacteria

Li, X.-Z., Plésiat, P., & Nikaido, H. (2015) · Clinical Microbiology Reviews · doi:10.1128/cmr.00117-14 · Cited by 1,648 · see citing works

A Sequencing Method Based on Real-Time Pyrophosphate

Ronaghi, M., Uhlén, M., & Nyrén, P. (1998) · Science · doi:10.1126/science.281.5375.363 · Cited by 1,630 · see citing works

GeneMark.hmm: new solutions for gene finding

Lukashin, A. (1998) · Nucleic Acids Research · doi:10.1093/nar/26.4.1107 · Cited by 1,536 · see citing works

Genome‐wide analysis of integral membrane proteins from eubacterial, archaean, and eukaryotic organisms

Wallin, E. J., & von HEIJNE, G. (1998) · Protein Science · doi:10.1002/pro.5560070420 · Cited by 1,536 · see citing works

Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima

Nelson, K. E., Clayton, R. A., Gill, S. R., Gwinn, M. L., Dodson, R. J., Haft, D. H., Hickey, E. K., Peterson, J. D., Nelson, W. C., Ketchum, K. A., et al. (1999) · Nature · doi:10.1038/20601 · Cited by 1,493 · see citing works

Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk

Wroblewski, L. E., Peek, R. M., & Wilson, K. T. (2010) · Clinical Microbiology Reviews · doi:10.1128/cmr.00011-10 · Cited by 1,455 · see citing works

The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus

Klenk, H., Clayton, R. A., Tomb, J.-F., White, O. R., Nelson, K. E., Ketchum, K. A., Dodson, R. J., Gwinn, M. L., Hickey, E. K., Peterson, J. D., et al. (1997) · Nature · doi:10.1038/37052 · Cited by 1,410 · see citing works

BLAST 2 Sequences, a new tool for comparing protein and nucleotide sequences

Tatusova, T. A., & Madden, T. L. (1999) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1999.tb13575.x · Cited by 1,789 · see citing works

Lipid A Modification Systems in Gram-Negative Bacteria

Raetz, C. R. H., Reynolds, C. M., Trent, M. S., & Bishop, R. E. (2007) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.76.010307.145803 · Cited by 1,336 · see citing works

Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS

Shigenobu, S., Watanabe, H., Hattori, M., Sakaki, Y., & Ishikawa, H. (2000) · Nature · doi:10.1038/35024074 · Cited by 1,338 · see citing works

Insertion Sequences

Mahillon, J., & Chandler, M. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.3.725-774.1998 · Cited by 1,292 · see citing works

Helicobacter pylori infection

Malfertheiner, P., Camargo, M. C., El-Omar, E. M., Liou, J., Peek, R. M., Schulz, C., Smith, S. I., & Suerbaum, S. (2023) · Nature Reviews Disease Primers · doi:10.1038/s41572-023-00431-8 · Cited by 1,285 · see citing works

Helicobacter pylori Adhesin Binding Fucosylated Histo-Blood Group Antigens Revealed by Retagging

Ilver, D., Arnqvist, A., Ögren, J., Frick, I.-M., Kersulyte, D., Incecik, E. T., Berg, D. E., Covacci, A., Engstrand, L. G., & Borén, T. (1998) · Science · doi:10.1126/science.279.5349.373 · Cited by 1,225 · see citing works

Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island

Viala, J., Chaput, C., Boneca, I. G., Cardona, A., Girardin, S. E., Moran, A. P., Athman, R., Mémet, S., Huerre, M., Coyle, A. J., et al. (2004) · Nature Immunology · doi:10.1038/ni1131 · Cited by 1,221 · see citing works

Biochemistry and Physiology of Cyclic Nucleotide Phosphodiesterases: Essential Components in Cyclic Nucleotide Signaling

Conti, M., & Beavo, J. A. (2007) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.76.060305.150444 · Cited by 1,188 · see citing works

Classification and phylogeny of hydrogenases

Vignais, P. M., Billoud, B., & Meyer, J. (2001) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2001.tb00587.x · Cited by 1,185 · see citing works

Helicobacter pylori: gastric cancer and beyond

Polk, D. B., & Peek, R. M. (2010) · Nature Reviews Cancer · doi:10.1038/nrc2857 · Cited by 1,158 · see citing works

The protein–protein interaction map of Helicobacter pylori

Rain, J., Selig, L., Reuse, H. D., Battaglia, V., Reverdy, C., Simon, S., Lenzen, G., Petel, F. X., Wojcik, J., Schächter, V., et al. (2001) · Nature · doi:10.1038/35051615 · Cited by 1,142 · see citing works

The primary transcriptome of the major human pathogen Helicobacter pylori

Sharma, C. M., Hoffmann, S., Darfeuille, F., Reignier, J., Findeiß, S., Sittka, A., Chabas, S., Reiche, K., Jörg Hackermüller, A., Reinhardt, R., et al. (2010) · Nature · doi:10.1038/nature08756 · Cited by 1,133 · see citing works

The complete genome of the hyperthermophilic bacterium Aquifex aeolicus

Deckert, G., Warren, P. V., Gaasterland, T., Young, W. G., Lenox, A. L., Graham, D. E., Overbeek, R., Snead, M. A., Keller, M., Aujay, M. A., et al. (1998) · Nature · doi:10.1038/32831 · Cited by 1,091 · see citing works

Complete Genome Sequence of Treponema pallidum , the Syphilis Spirochete

Fraser, C. M., Norris, S. J., Weinstock, G. M., White, O. R., Sutton, G. G., Dodson, R. J., Gwinn, M. L., Hickey, E. K., Clayton, R. A., Ketchum, K. A., et al. (1998) · Science · doi:10.1126/science.281.5375.375 · Cited by 1,075 · see citing works

Molecular aspects of bacterial pH sensing and homeostasis

KRULWICH, T. A., Sachs, G. M., & Padan, E. (2011) · Nature Reviews Microbiology · doi:10.1038/nrmicro2549 · Cited by 1,051 · see citing works

Helicobacter pylori Virulence and Genetic Geography

Covacci, A., Telford, J. L., Giudice, G. D., Parsonnet, J., & Rappuoli, R. (1999) · Science · doi:10.1126/science.284.5418.1328 · Cited by 1,047 · see citing works

Conservation of gene order: a fingerprint of proteins that physically interact

Dandekar, T. (1998) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(98)01274-2 · Cited by 1,037 · see citing works

Microbial gene identification using interpolated Markov models

Salzberg, S. L., Delcher, A. L., Kasif, S., & White, O. R. (1998) · Nucleic Acids Research · doi:10.1093/nar/26.2.544 · Cited by 989 · see citing works

Helicobacter pylori persistence: biology and disease

Blaser, M. J., & Atherton, J. C. (2004) · Journal of Clinical Investigation · doi:10.1172/jci20925 · Cited by 941 · see citing works

Helicobacter pylori SabA Adhesin in Persistent Infection and Chronic Inflammation

Mahdavi, J., Sondén, B., Hurtig, M., Olfat, F. O., Forsberg, L., Roche, N., Ångström, J., Larsson, T. P., Teneberg, S., Karlsson, K., et al. (2002) · Science · doi:10.1126/science.1069076 · Cited by 935 · see citing works

Global Transposon Mutagenesis and a Minimal Mycoplasma Genome

Hutchison, C. A., Peterson, S. N., Gill, S. R., Cline, R. T., White, O. R., Fraser, C. M., Smith, H. O., & Venter, J. C. (1999) · Science · doi:10.1126/science.286.5447.2165 · Cited by 925 · see citing works

The dynamic range of protein expression: A challenge for proteomic research

Corthals, G. L., Wasinger, V. C., Hochstrasser, D. F., & Sanchez, J. (2000) · Electrophoresis · doi:10.1002/(sici)1522-2683(20000401)21:6 · Cited by 615 · see citing works

Type V Protein Secretion Pathway: the Autotransporter Story

Henderson, I. R., Navarro‐García, F., Desvaux, M., Fernandez, R. C., & Ala’Aldeen, D. A. A. (2004) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.68.4.692-744.2004 · Cited by 839 · see citing works

A bacterial genome in flux: the twelve linear and nine circular extrachromosomal DNAs in an infectious isolate of the Lyme disease spirochete Borrelia burgdorferi

Casjens, S., Palmer, N., van Vugt, R., Huang, W. M., Stevenson, B., Rosa, P. A., Lathigra, R. B., Sutton, G. G., Peterson, J. D., Dodson, R. J., et al. (2000) · Molecular Microbiology · doi:10.1046/j.1365-2958.2000.01698.x · Cited by 834 · see citing works

Bacterial Topoisomerase Inhibitors: Quinolone and Pyridone Antibacterial Agents

Mitscher, L. A. (2005) · Chemical Reviews · doi:10.1021/cr030101q · Cited by 788 · see citing works

Pathogenicity Islands in BacterialPathogenesis

Schmidt, H., & Hensel, M. (2004) · Clinical Microbiology Reviews · doi:10.1128/cmr.17.1.14-56.2004 · Cited by 776 · see citing works

Phase and Antigenic Variation in Bacteria

van der Woude, M. W., & Bäumler, A. J. (2004) · Clinical Microbiology Reviews · doi:10.1128/cmr.17.3.581-611.2004 · Cited by 766 · see citing works

The human gut microbiome: ecology and recent evolutionary changes

Walter, J., & Ley, R. (2011) · Annual Review of Microbiology · doi:10.1146/annurev-micro-090110-102830 · Cited by 720 · see citing works

Analyses of the cag pathogenicity island of Helicobacter pylori

Akopyants, N. S., Clifton, S. W., Kersulyte, D., Crabtree, J. E., Youree, B. E., Reece, C. A., Bukanov, N. O., Drazek, E. S., Roe, B. A., & Berg, D. E. (1998) · Molecular Microbiology · doi:10.1046/j.1365-2958.1998.00770.x · Cited by 716 · see citing works

Genome phylogeny based on gene content

Snel, ‎., Peer Bork, B., & Huynen, M. A. (1999) · Nature Genetics · doi:10.1038/5052 · Cited by 708 · see citing works

RIBONUCLEOTIDE REDUCTASES

Jordan, A., & Reichard, P. A. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.71 · Cited by 675 · see citing works

[34] GATEWAY recombinational cloning: Application to the cloning of large numbers of open reading frames or ORFeomes

Walhout, A. J. M., Temple, G. F., Brasch, M. A., Hartley, J. L., Lorson, M. A., van den Heuvel, S., & Vidal, M. (2000) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(00)28419-x · Cited by 644 · see citing works

Creating and Maintaining the Gastrointestinal Ecosystem: What We Know and Need To Know from Gnotobiology

Falk, P. G., Hooper, L. V., Midtvedt, T., & Gordon, J. I. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.4.1157-1170.1998 · Cited by 643 · see citing works

Multimodular Penicillin-Binding Proteins: An Enigmatic Family of Orthologs and Paralogs

Goffin, C., & Ghuysen, J. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.4.1079-1093.1998 · Cited by 631 · see citing works

Phylogenomics: Improving Functional Predictions for Uncharacterized Genes by Evolutionary AnalysisPreprint

Eisen, J. A. (1998) · Genome Research · doi:10.1101/gr.8.3.163 · Cited by 628 · see citing works

Genome sequence of the endocellular obligate symbiont of tsetse flies, Wigglesworthia glossinidia

Akman, L., Yamashita, A., Watanabe, H., Oshima, K., Shiba, T., Hattori, M., & Aksoy, S. (2002) · Nature Genetics · doi:10.1038/ng986 · Cited by 613 · see citing works

Cyclopropane ring formation in membrane lipids of bacteria

Grogan, D. W., & Cronan, J. E. (1997) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.61.4.429-441.1997 · Cited by 612 · see citing works

Hydrolysis and amino acid composition analysis of proteins

Fountoulakis, M., & Lahm, H.-W. (1998) · Journal of Chromatography A · doi:10.1016/s0021-9673(98)00721-3 · Cited by 606 · see citing works

Protein Phylogenies and Signature Sequences: A Reappraisal of Evolutionary Relationships among Archaebacteria, Eubacteria, and Eukaryotes

Gupta, R. S. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.4.1435-1491.1998 · Cited by 598 · see citing works

Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cag -driven host cell translocation

Stein, M., Rappuoli, R., & Covacci, A. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.3.1263 · Cited by 578 · see citing works

THE PATHOGENESIS OFHELICOBACTER PYLORI–INDUCED GASTRO-DUODENAL DISEASES

Atherton, J. C. (2006) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev.pathol.1.110304.100125 · Cited by 568 · see citing works

Macrolide Resistance Conferred by Base Substitutions in 23S rRNA

Vester, B., & Douthwaite, S. R. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.1.1-12.2001 · Cited by 562 · see citing works

A whole-genome microarray reveals genetic diversity among Helicobacter pylori strains

Salama, N. R., Guillemin, K. J., McDaniel, T. K., Sherlock, G. J., Tompkins, L. S., & Falkow, S. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.26.14668 · Cited by 559 · see citing works

Helicobacter infection and gastric neoplasia

Peek, R. M., & Crabtree, J. E. (2005) · The Journal of Pathology · doi:10.1002/path.1868 · Cited by 549 · see citing works

Coadaptation of Helicobacter pylori and humans: ancient history, modern implications

Atherton, J. C., & Blaser, M. J. (2009) · Journal of Clinical Investigation · doi:10.1172/jci38605 · Cited by 549 · see citing works

Essential Genes Are More Evolutionarily Conserved Than Are Nonessential Genes in BacteriaPreprint

Jordan, I. K., Rogozin, I. B., Wolf, Y. I., & Koonin, E. V. (2002) · Genome Research · doi:10.1101/gr.87702 · Cited by 546 · see citing works

Bacterial respiration: a flexible process for a changing environment 1999 Fleming Lecture (Delivered at the 144th meeting of the Society for General Microbiology, 8 September 1999)

Richardson, D. J. (2000) · Microbiology · doi:10.1099/00221287-146-3-551 · Cited by 544 · see citing works

Surface Charge-Switching Polymeric Nanoparticles for Bacterial Cell Wall-Targeted Delivery of Antibiotics

Radovic‐Moreno, A. F., Lu, T. K., Puscasu, V. A., Yoon, S.-S., Langer, R., & Farokhzad, O. C. (2012) · ACS Nano · doi:10.1021/nn3008383 · Cited by 542 · see citing works

Transmembrane Signaling across the Ligand-Gated FhuA Receptor

Locher, K. P., Rees, B., Koebnik, R., Mitschler, A., Moulinier, L., Rosenbusch, J. P., & Moras, D. (1998) · Cell · doi:10.1016/s0092-8674(00)81700-6 · Cited by 540 · see citing works

Major Structural Differences and Novel Potential Virulence Mechanisms from the Genomes of Multiple Campylobacter Species

Fouts, D. E., Mongodin, E. F., Mandrell, R. E., Miller, W. G., Rasko, D. A., Ravel, J., Brinkac, L. M., DeBoy, R. T., Parker, C. T., Daugherty, S. C., et al. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0030015 · Cited by 539 · see citing works

Living dangerously: how Helicobacter pylori survives in the human stomach

Montecucco, C., & Rappuoli, R. (2001) · Nature Reviews Molecular Cell Biology · doi:10.1038/35073084 · Cited by 538 · see citing works

α-Crystallin-Type Heat Shock Proteins: Socializing Minichaperones in the Context of a Multichaperone Network

Narberhaus, F. (2002) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.66.1.64-93.2002 · Cited by 534 · see citing works

Conserved pathways within bacteria and yeast as revealed by global protein network alignment

Kelley, B. P., Sharan, R., Karp, R. M., Sittler, T., Root, D. E., Stockwell, B. R., & Ideker, T. E. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1534710100 · Cited by 527 · see citing works

Mechanisms of Action of Antimicrobials: Focus on Fluoroquinolones

Hooper, D. C. (2001) · Clinical Infectious Diseases · doi:10.1086/319370 · Cited by 522 · see citing works

Behavior of restriction–modification systems as selfish mobile elements and their impact on genome evolution

Kobayashi, I. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.18.3742 · Cited by 513 · see citing works

Systematic mutagenesis of the Helicobacter pylori cag pathogenicity island: essential genes for CagA translocation in host cells and induction of interleukin‐8

Fischer, W. H., Püls, J., Buhrdorf, R., Gebert, B., Odenbreit, S., & Haas, R. (2001) · Molecular Microbiology · doi:10.1046/j.1365-2958.2001.02714.x · Cited by 506 · see citing works

O-antigen structural variation: mechanisms and possible roles in animal/plant–microbe interactions

Lerouge, I., & Vanderleyden, J. (2002) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2002.tb00597.x · Cited by 504 · see citing works

Purine nucleoside phosphorylases: properties, functions, and clinical aspects

Bzowska, A., Kulikowska, E., & Shugar, D. (2000) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(00)00097-8 · Cited by 494 · see citing works

Eubacterial sigma-factors

Wösten, M. M. S. M. (1998) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.1998.tb00364.x · Cited by 493 · see citing works

Mechanisms of fluoroquinolone resistance

Hooper, D. C. (1999) · Drug Resistance Updates · doi:10.1054/drup.1998.0068 · Cited by 490 · see citing works

Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium

Matsumoto, Y. M., Marusawa, H., Kinoshita, K., Endo, Y., Kou, T., Morisawa, T., Azuma, T., Okazaki, I., Honjo, T., & Chiba, T. (2007) · Nature Medicine · doi:10.1038/nm1566 · Cited by 480 · see citing works

A phylogenomic study of DNA repair genes, proteins, and processes

Eisen, J. A., & Hanawalt, P. C. (1999) · Mutation Research/DNA Repair · doi:10.1016/s0921-8777(99)00050-6 · Cited by 464 · see citing works

Within-host evolution of bacterial pathogens

Didelot, X., Walker, A. S., Peto, T., Crook, D. W., & Wilson, D. J. (2016) · Nature Reviews Microbiology · doi:10.1038/nrmicro.2015.13 · Cited by 462 · see citing works

Global regulation by the small RNA‐binding protein CsrA and the non‐coding RNA molecule CsrB

Romeo, T. (1998) · Molecular Microbiology · doi:10.1046/j.1365-2958.1998.01021.x · Cited by 456 · see citing works

Microbial stress response in minimal processing

Abee, T. (1999) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(99)00078-1 · Cited by 450 · see citing works

Similarities and differences among 105 members of the Int family of site-specific recombinases

Nunes-Düby, S. E., Kwon, H. J., Tirumalai, R. S., Ellenberger, T., & Landy, A. (1998) · Nucleic Acids Research · doi:10.1093/nar/26.2.391 · Cited by 448 · see citing works

Type I Restriction Systems: Sophisticated Molecular Machines (a Legacy of Bertani and Weigle)

Murray, N. E. (2000) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.64.2.412-434.2000 · Cited by 447 · see citing works

Geographic distribution of vacA allelic types of Helicobacter pylori

van Doorn, L., Figueiredo, C., Mégraud, F., Peña, A. S., Midolo, P. D., Queiroz, D. M. M., Carneiro, F., Vanderborght, B., Pegado, M. D. G. F., Sanna, R., et al. (1999) · Gastroenterology · doi:10.1016/s0016-5085(99)70065-x · Cited by 441 · see citing works

Analyzing genomes with cumulative skew diagrams

Grigoriev, A. (1998) · Nucleic Acids Research · doi:10.1093/nar/26.10.2286 · Cited by 441 · see citing works

Measuring genome evolution

Huynen, M. A., & Peer Bork, B. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.11.5849 · Cited by 439 · see citing works

Bacterial contingency loci: the role of simple sequence DNA repeats in bacterial adaptation

Moxon, R., Bayliss, C., & Hood, D. (2006) · Annual Review of Genetics · doi:10.1146/annurev.genet.40.110405.090442 · Cited by 438 · see citing works

A homologue of the Agrobacterium tumefaciens VirB and Bordetella pertussis Ptl type IV secretion systems is essential for intracellular survival of Brucella suis

O’Callaghan, D., Cazevieille, C., Allardet-Servent, A., Boschiroli, M. L., Bourg, G., Foulongne, V., Frutos, P., Константинович, К. Ю., & Ramuz, M. (1999) · Molecular Microbiology · doi:10.1046/j.1365-2958.1999.01569.x · Cited by 438 · see citing works

Systems Properties of the Haemophilus influenzaeRd Metabolic Genotype

Edwards, J. S., & Palsson, B. Ø. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.25.17410 · Cited by 434 · see citing works

THE PROTEASOME

Bochtler, M., Ditzel, L., Groll, M., Hartmann, C., & Huber, R. (1999) · Annual Review of Biophysics and Biomolecular Structure · doi:10.1146/annurev.biophys.28.1.295 · Cited by 433 · see citing works

Recombination and mutation during long-term gastric colonization by Helicobacter pylori : Estimates of clock rates, recombination size, and minimal age

Falush, D., Kraft, C., Taylor, N. S., Correa, P., Fox, J. G., Achtman, M., & Suerbaum, S. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.251396098 · Cited by 429 · see citing works

Predicting function: from genes to genomes and back 1 1Edited by P. E. Wright

Peer Bork, B., Dandekar, T., Diaz-Lazcoz, Y., Eisenhaber, F., Huynen, M. A., & Yuan, Y. P. (1998) · Journal of Molecular Biology · doi:10.1006/jmbi.1998.2144 · Cited by 422 · see citing works

Helicobacter pylori in peptic ulcer

Vural, H. C. (2006) · Journal of Human Sciences · Cited by 1 · see citing works

Metabolism and Genetics of Helicobacter pylori : the Genome Era

Marais, A., Mendz, G. L., Hazell, S. L., & Mégraud, F. (1999) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.63.3.642-674.1999 · Cited by 199 · see citing works

Evolved to vary: genome and epigenome variation in the human pathogenHelicobacter pylori

Ailloud, F., Estibariz, I., & Suerbaum, S. (2020) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuaa042 · Cited by 39 · see citing works

Contributions of Genome Sequencing to Understanding the Biology ofHelicobacter pylori

Ge, Z., & Taylor, D. E. (1999) · Annual Review of Microbiology · doi:10.1146/annurev.micro.53.1.353 · Cited by 71 · see citing works

New Implications on Genomic Adaptation Derived from the Helicobacter pylori Genome Comparison

Lara-Ramirez, E. E., Segura‐Cabrera, A., Guo, X., Yu, G.-X., García-Pérez, C. A., & Rodríguez-Pérez, M. A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017300 · Cited by 22 · see citing works