The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Homing endonucleases: structural and functional insight into the catalysts of intron/intein mobility
Open accessAbstract
Homing endonucleases confer mobility to their host intervening sequence, either an intron or intein, by catalyzing a highly specific double-strand break in a cognate allele lacking the intervening sequence. These proteins are characterized by their ability to bind long DNA target sites (14-40 bp) and their tolerance of minor sequence changes in these sites. A wealth of biochemical and structural data has been generated for these enzymes over the past few years. Herein we review our current understanding of homing endonucleases, including their diversity and evolution, DNA-binding and catalytic mechanisms, and attempts to engineer them to bind novel DNA substrates.
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Cites
In vivo repression by a site-specific DNA-binding protein designed against an oncogenic sequence
Choo, Y., Sánchez-García, I., & Klug, A. (1994) · Nature · doi:10.1038/372642a0 · Cited by 292
Argast, G. M., Stephens, K. M., Emond, M. J., & Monnat, R. J. (1998) · Journal of Molecular Biology · doi:10.1006/jmbi.1998.1886 · Cited by 127
Degenerate DNA recognition by I-PpoI endonuclease
Wittmayer, P. K., McKenzie, J. L., & Raines, R. T. (1998) · Gene · doi:10.1016/s0378-1119(97)00563-5 · Cited by 36
Cited by
Gene targeting using zinc finger nucleases
Porteus, M. H., & Carroll, D. (2005) · Nature Biotechnology · doi:10.1038/nbt1125 · Cited by 641
Making and Breaking Nucleic Acids: Two-Mg2+-Ion Catalysis and Substrate Specificity
Yang, W., Lee, J. Y., & Nowotny, M. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.03.013 · Cited by 573
The pyocins of Pseudomonas aeruginosa
Michel-Briand, Y., & Baysse, C. (2002) · Biochimie · doi:10.1016/s0300-9084(02)01422-0 · Cited by 560
A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences
Smith, J., Grizot, S., Arnould, S., Duclert, A., Epinat, J.-C., Chames, P., Prieto, J., Redondo, P., Blanco, F. J., Bravo, J., et al. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl720 · Cited by 329
Advances in Mammalian cell line development technologies for recombinant protein production
Lai, T., Yang, Y., & Ng, S. (2013) · Pharmaceuticals · doi:10.3390/ph6050579 · Cited by 322
Metadata
- Authors
- Chevalier, B. S.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2001-09-15
- Volume
- 29
- Issue
- 18
- Pages
- 3757-3774
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W2165011963
- Cited by
- 483
- References
- 3
- FWCI
- 9.66
- Type
- journal article
- Language
- en
- Open access
- green
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