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Cited by 2,080

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CD-Search: protein domain annotations on the fly

Open access
Marchler-Bauer, A., Bryant, S. H.·2004·Nucleic Acids Research

Abstract

We describe the Conserved Domain Search service (CD-Search), a web-based tool for the detection of structural and functional domains in protein sequences. CD-Search uses BLAST(R) heuristics to provide a fast, interactive service, and searches a comprehensive collection of domain models. Search results are displayed as domain architecture cartoons and pairwise alignments between the query and domain-model consensus sequences. Search results may be visualized in further detail by embedding the query sequence into multiple alignment displays and by mapping onto three-dimensional molecular graphic displays of known structures within the domain family. CD-Search can be accessed at http://www.ncbi.nlm.nih.gov/Structure/cdd/wrpsb.cgi.

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Metadata

Authors
Marchler-Bauer, A., & Bryant, S. H.
Venue
Nucleic Acids Research
Published
2004-07-01
Volume
32
Issue
Web Server
Pages
W327-W331
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W2004589024
Cited by
2,080
References
1
FWCI
41.44
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: CD-Search: protein domain annotations on the fly. https://app.cochat.ai/papers/10.1093/nar/gkh454
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Marchler-Bauer, A., & Bryant, S. H. (2004). CD-Search: protein domain annotations on the fly. Nucleic Acids Research. https://doi.org/10.1093/nar/gkh454

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