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CD-Search: protein domain annotations on the fly
Open accessAbstract
We describe the Conserved Domain Search service (CD-Search), a web-based tool for the detection of structural and functional domains in protein sequences. CD-Search uses BLAST(R) heuristics to provide a fast, interactive service, and searches a comprehensive collection of domain models. Search results are displayed as domain architecture cartoons and pairwise alignments between the query and domain-model consensus sequences. Search results may be visualized in further detail by embedding the query sequence into multiple alignment displays and by mapping onto three-dimensional molecular graphic displays of known structures within the domain family. CD-Search can be accessed at http://www.ncbi.nlm.nih.gov/Structure/cdd/wrpsb.cgi.
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Metadata
- Authors
- Marchler-Bauer, A., & Bryant, S. H.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2004-07-01
- Volume
- 32
- Issue
- Web Server
- Pages
- W327-W331
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W2004589024
- Cited by
- 2,080
- References
- 1
- FWCI
- 41.44
- Type
- journal article
- Language
- en
- Open access
- hybrid
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