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Cited by 252

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Target prediction for small, noncoding RNAs in bacteria

Open access
Tjaden, B., Goodwin, S. S., Opdyke, J. A., Guillier, M., Fu, D. X., Gottesman, S., Storz, G.·2006·Nucleic Acids Research

Abstract

Many small, noncoding RNAs in bacteria act as post-transcriptional regulators by basepairing with target mRNAs. While the number of characterized small RNAs (sRNAs) has steadily increased, only a limited number of the corresponding mRNA targets have been identified. Here we present a program, TargetRNA, that predicts the targets of these bacterial RNA regulators. The program was evaluated by assessing whether previously known targets could be identified. The program was then used to predict targets for the Escherichia coli RNAs RyhB, OmrA, OmrB and OxyS, and the predictions were compared with changes in whole genome expression patterns observed upon expression of the sRNAs. Our results show that TargetRNA is a useful tool for finding mRNA targets of sRNAs, although its rate of success varies between sRNAs.

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Metadata

Authors
Tjaden, B., Goodwin, S. S., Opdyke, J. A., Guillier, M., Fu, D. X., Gottesman, S., & Storz, G.
Venue
Nucleic Acids Research
Published
2006-05-22
Volume
34
Issue
9
Pages
2791-2802
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W2139271133
Cited by
252
References
5
FWCI
10.43
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Target prediction for small, noncoding RNAs in bacteria. https://app.cochat.ai/papers/10.1093/nar/gkl356
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Tjaden, B., Goodwin, S. S., Opdyke, J. A., Guillier, M., Fu, D. X., Gottesman, S., & Storz, G. (2006). Target prediction for small, noncoding RNAs in bacteria. Nucleic Acids Research. https://doi.org/10.1093/nar/gkl356

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