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RNAdb 2.0--an expanded database of mammalian non-coding RNAs
Open accessAbstract
RNAdb is a comprehensive database of mammalian non-protein-coding RNAs (ncRNAs). There is increasing recognition that ncRNAs play important regulatory roles in multicellular organisms, and there is an expanding rate of discovery of novel ncRNAs as well as an increasing allocation of function. In this update to RNAdb, we provide nucleotide sequences and annotations for tens of thousands of non-housekeeping ncRNAs, including a wide range of mammalian microRNAs, small nucleolar RNAs and larger mRNA-like ncRNAs. Some of these have documented functions and/or expression patterns, but the majority remain of unclear significance, and include PIWI-interacting RNAs, ncRNAs identified from the latest rounds of large-scale cDNA sequencing projects, putative antisense transcripts, as well as ncRNAs predicted on the basis of structural features and alignments. Improvements to the database comprise not only new and updated ncRNA datasets, but also provision of microarray-based expression data and closer interface with more specialized ncRNA resources such as miRBase and snoRNA-LBME-db. To access RNAdb, visit http://research.imb.uq.edu.au/RNAdb.
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A gene atlas of the mouse and human protein-encoding transcriptomes
Su, A. I., Wiltshire, T., Batalov, S., Lapp, H., Ching, K. A., Block, D., Zhang, J., Soden, R., Hayakawa, M., Kreiman, G., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0400782101 · Cited by 3,475
A germline-specific class of small RNAs binds mammalian Piwi proteins
Girard, A., Sachidanandam, R., Hannon, G. J., & Carmell, M. A. (2006) · Nature · doi:10.1038/nature04917 · Cited by 1,762
A novel class of small RNAs bind to MILI protein in mouse testes
Aravin, A., Gaidatzis, D., Pfeffer, S., Lagos-Quintana, M., Landgraf, P., Iovino, N., Morris, P., Brownstein, M. J., Kuramochi-Miyagawa, S., Nakano, T., et al. (2006) · Nature · doi:10.1038/nature04916 · Cited by 1,516
An RNA gene expressed during cortical development evolved rapidly in humans
Pollard, K. S., Salama, S. R., Lambert, N., Lambot, M.-A., Coppens, S., Pedersen, J. S., Katzman, S., King, B., Onodera, C., Siepel, A., et al. (2006) · Nature · doi:10.1038/nature05113 · Cited by 1,005
Feng, J., Bi, C., Clark, B. S., Mady, R., Shah, P., & Kohtz, J. D. (2006) · Genes & Development · doi:10.1101/gad.1416106 · Cited by 712
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CPC2: a fast and accurate coding potential calculator based on sequence intrinsic features
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Methodological challenges in utilizing mi RNA s as circulating biomarkers
Moldovan, L., Batte, K. E., Trgovcich, J., Wisler, J., Marsh, C. B., & Piper, M. (2014) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.12236 · Cited by 436
The role of microRNAs in cancer: No small matter
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Origin of primate orphan genes: a comparative genomics approach
Toll-Riera, M., Bosch, N., Bellora, N., Castelo, R., Armengol, L., Estivill, X., & Mar Alba, M. (2008) · Molecular Biology and Evolution · doi:10.1093/molbev/msn281 · Cited by 218
Diverse human extracellular RNAs are widely detected in human plasma
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Metadata
- Authors
- Pang, K. C., Stephen, S., Dinger, M. E., Engstrom, P. G., Lenhard, B., & Mattick, J. S.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-01-03
- Volume
- 35
- Issue
- Database
- Pages
- D178-D182
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W2159006685
- Cited by
- 166
- References
- 5
- FWCI
- 4.69
- Type
- journal article
- Language
- en
- Open access
- gold
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- Pang, K. C., Stephen, S., Dinger, M. E., Engstrom, P. G., Lenhard, B., & Mattick, J. S. (2007). RNAdb 2.0--an expanded database of mammalian non-coding RNAs. Nucleic Acids Research. https://doi.org/10.1093/nar/gkl926
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