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InParanoid 6: eukaryotic ortholog clusters with inparalogs

Open access
Berglund, A.-C., Sjolund, E., Ostlund, G., Sonnhammer, E. L. L.·2007·Nucleic Acids Research

Abstract

The InParanoid eukaryotic ortholog database (http://InParanoid.sbc.su.se/) has been updated to version 6 and is now based on 35 species. We collected all available 'complete' eukaryotic proteomes and Escherichia coli, and calculated ortholog groups for all 595 species pairs using the InParanoid program. This resulted in 2 642 187 pairwise ortholog groups in total. The orthology-based species relations are presented in an orthophylogram. InParanoid clusters contain one or more orthologs from each of the two species. Multiple orthologs in the same species, i.e. inparalogs, result from gene duplications after the species divergence. A new InParanoid website has been developed which is optimized for speed both for users and for updating the system. The XML output format has been improved for efficient processing of the InParanoid ortholog clusters.

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Metadata

Authors
Berglund, A.-C., Sjolund, E., Ostlund, G., & Sonnhammer, E. L. L.
Venue
Nucleic Acids Research
Published
2007-12-23
Volume
36
Issue
Database
Pages
D263-D266
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W2142045367
Cited by
221
References
3
FWCI
9.34
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: InParanoid 6: eukaryotic ortholog clusters with inparalogs. https://app.cochat.ai/papers/10.1093/nar/gkm1020
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Berglund, A.-C., Sjolund, E., Ostlund, G., & Sonnhammer, E. L. L. (2007). InParanoid 6: eukaryotic ortholog clusters with inparalogs. Nucleic Acids Research. https://doi.org/10.1093/nar/gkm1020

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