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The microRNA.org resource: targets and expression

Open access
Betel, D., Wilson, M., Gabow, A., Marks, D. S., Sander, C.·2007·Nucleic Acids Research

Abstract

MicroRNA.org (http://www.microrna.org) is a comprehensive resource of microRNA target predictions and expression profiles. Target predictions are based on a development of the miRanda algorithm which incorporates current biological knowledge on target rules and on the use of an up-to-date compendium of mammalian microRNAs. MicroRNA expression profiles are derived from a comprehensive sequencing project of a large set of mammalian tissues and cell lines of normal and disease origin. Using an improved graphical interface, a user can explore (i) the set of genes that are potentially regulated by a particular microRNA, (ii) the implied cooperativity of multiple microRNAs on a particular mRNA and (iii) microRNA expression profiles in various tissues. To facilitate future updates and development, the microRNA.org database structure and software architecture is flexibly designed to incorporate new expression and target discoveries. The web resource provides users with functional information about the growing number of microRNAs and their interaction with target genes in many species and facilitates novel discoveries in microRNA gene regulation.

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Metadata

Authors
Betel, D., Wilson, M., Gabow, A., Marks, D. S., & Sander, C.
Venue
Nucleic Acids Research
Published
2007-12-23
Volume
36
Issue
Database
Pages
D149-D153
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W2044832480
Cited by
2,503
References
4
FWCI
18.96
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: The microRNA.org resource: targets and expression. https://app.cochat.ai/papers/10.1093/nar/gkm995
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Betel, D., Wilson, M., Gabow, A., Marks, D. S., & Sander, C. (2007). The microRNA.org resource: targets and expression. Nucleic Acids Research. https://doi.org/10.1093/nar/gkm995

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