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Cited by 341

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

The triple helix: 50 years later, the outcome

Open access
Duca, Maria, Vekhoff, Pierre, Oussedik, Kahina, Halby, Ludovic, Arimondo, Paola B.·2008·Nucleic Acids Research

Abstract

Triplex-forming oligonucleotides constitute an interesting DNA sequence-specific tool that can be used to target cleaving or cross-linking agents, transcription factors or nucleases to a chosen site on the DNA. They are not only used as biotechnological tools but also to induce modifications on DNA with the aim to control gene expression, such as by site-directed mutagenesis or DNA recombination. Here, we report the state of art of the triplex-based antigene strategy 50 years after the discovery of such a structure, and we show the importance of the actual applications and the main challenges that we still have ahead of us.

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Crossref · 10.1093/nar/gkn493

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Metadata

Authors
Duca, M., Vekhoff, P., Oussedik, K., Halby, L., & Arimondo, P. B.
Venue
Nucleic Acids Research
Published
2008-08-01
Volume
36
Issue
16
Pages
5123-5138
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W2119970960
Cited by
341
References
4
FWCI
9.31
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: The triple helix: 50 years later, the outcome. https://app.cochat.ai/papers/10.1093/nar/gkn493
The paper
Duca, M., Vekhoff, P., Oussedik, K., Halby, L., & Arimondo, P. B. (2008). The triple helix: 50 years later, the outcome. Nucleic Acids Research. https://doi.org/10.1093/nar/gkn493

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.