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MCScanX: a toolkit for detection and evolutionary analysis of gene synteny and collinearity
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The physical position of homologs offers a second line of evidence that can help overcome challenges posed by WGDs, tandem arrays, heterozygous-duplicated regions, and other genomic complexities.
“The physical position of homologs offers a second line of evidence that can help overcome challenges posed by WGDs, tandem arrays, heterozygous-duplicated regions, and other genomic complexities (Drillon et al., 2020; Haug-Baltzell et al., 2017; Wang et al., 2012).”
From GENESPACE tracks regions of interest and gene copy number variation across multiple genomes (2022) · cites this paper as Wang et al., 2012
The Methods section, “Classification of duplicate gene origins,” uses chromosome order and collinear position to distinguish tandem from WGD/segmental duplicates, supporting the value of homolog position for those complexities. The passages do not address heterozygous-duplicated regions or show that positional evidence overcomes that challenge; page numbers were unavailable in our copy. (LLM, conf=0.86)
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Basic local alignment search tool
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GENESPACE tracks regions of interest and gene copy number variation across multiple genomes
Lovell, J. T., Sreedasyam, A., Schranz, M. E., Wilson, M., Carlson, J. W., Harkess, A., Emms, D., Goodstein, D. M., & Schmutz, J. (2022) · eLife · doi:10.7554/elife.78526 · Cited by 391
Deeply conserved synteny and the evolution of metazoan chromosomes
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Inferring synteny between genome assemblies: a systematic evaluation
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Genome-Wide Signatures of Adaptation to Extreme Environments in Red Algae
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Metadata
- Authors
- Wang, Y., Tang, H., DeBarry, J. D., Tan, X., Li, J., Wang, X., Lee, T.-H., Jin, H., Marler, B., Guo, H., Kissinger, J. C., & Paterson, A. H.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-01-04
- Volume
- 40
- Issue
- 7
- Pages
- e49-e49
- ISSN
- 0305-1048
- 1362-4962
- PMC
- PMC3326336
- Cited by
- 7,093
- References
- 4
- Language
- en
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